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Literature DB >> 29422262

AMPK Wars: the VMH Strikes Back, Return of the PVH.

Abstract

Hypothalamic AMP-activated protein kinase (AMPK) is an important modulator of whole-body energy homeostasis, particularly within the ventromedial nucleus, where it regulates energy expenditure, glucose, and lipid metabolism. A recent paper in Cell Reports has demonstrated that AMPK in the paraventricular nucleus of the hypothalamus modulates dietary preference for carbohydrate over fat.

Entities: Chemical Disease Gene

Keywords: AMPK; carbohydrate; feeding; paraventricular nucleus of the hypothalamus

Mesh：

Substances：

Year: 2018 PMID： 29422262 DOI： 10.1016/j.tem.2018.01.004

Source DB: PubMed Journal: Trends Endocrinol Metab ISSN： 1043-2760 Impact factor: 12.015

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Cited

6 in total

1. Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation.

Authors: Edward Milbank; Nathalia R V Dragano; Ismael González-García; Marcos Rios Garcia; Verónica Rivas-Limeres; Liliana Perdomo; Grégory Hilairet; Francisco Ruiz-Pino; Patricia Mallegol; Donald A Morgan; Ramón Iglesias-Rey; Cristina Contreras; Luisa Vergori; Juan Cuñarro; Begoña Porteiro; Aleix Gavaldà-Navarro; Rebecca Oelkrug; Anxo Vidal; Juan Roa; Tomás Sobrino; Francesc Villarroya; Carlos Diéguez; Rubén Nogueiras; Cristina García-Cáceres; Manuel Tena-Sempere; Jens Mittag; M Carmen Martínez; Kamal Rahmouni; Ramaroson Andriantsitohaina; Miguel López
Journal: Nat Metab Date: 2021-10-21

2. SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity.

Authors: Patricia Seoane-Collazo; Juan Roa; Eva Rial-Pensado; Laura Liñares-Pose; Daniel Beiroa; Francisco Ruíz-Pino; Tania López-González; Donald A Morgan; José Ángel Pardavila; María Jesús Sánchez-Tapia; Noelia Martínez-Sánchez; Cristina Contreras; Miguel Fidalgo; Carlos Diéguez; Roberto Coppari; Kamal Rahmouni; Rubén Nogueiras; Manuel Tena-Sempere; Miguel López
Journal: Diabetes Date: 2018-08-13 Impact factor: 9.461

3. Resistance Exercise Training Attenuates the Loss of Endogenous GLP-1 Receptor in the Hypothalamus of Type 2 Diabetic Rats.

Authors: Se Hwan Park; Jin Hwan Yoon; Dae Yun Seo; Tae Nyun Kim; Jeong Rim Ko; Jin Han
Journal: Int J Environ Res Public Health Date: 2019-03-07 Impact factor: 3.390

AMPK Wars: the VMH Strikes Back, Return of the PVH.

1. Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation.

2. SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity.

3. Resistance Exercise Training Attenuates the Loss of Endogenous GLP-1 Receptor in the Hypothalamus of Type 2 Diabetic Rats.

4. Activity-Based Anorexia Induces Browning of Adipose Tissue Independent of Hypothalamic AMPK.

Review 5. Hypothalamic AMPK and energy balance.

Review 6. Understanding the Effects of Antipsychotics on Appetite Control.