Literature DB >> 2941916

Immunohistological study of histiocytic necrotizing lymphadenitis.

M Kikuchi, M Takeshita, K Tashiro, T Mitsui, T Eimoto, S Okamura.   

Abstract

Immunohistological study of 18 cases of histiocytic necrotizing lymphadenitis (HNL) demonstrated numerous helper/inducer cells (OKT-4) and suppressor/cytotoxic cells (OKT-8) with activation (Tac) and proliferation (OKT-9) markers, and histiocytes (lysozyme, alpha-1 anti-chymotrypsin, OK-M1) in the affected areas. However, B cells (B-1), NK cells (Leu-7 and Leu-11), complement proteins and receptor (C4 and C3d receptor), and neutrophils (chloroacetate esterase) were scanty or absent in these foci. Activity of NK cells was also decreased in the peripheral blood of 2 cases examined. The results suggest that HNL might be induced by the abnormal T cell-histiocyte response against some causative agents which induce a similar reaction of delayed hypersensitivity type.

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Year:  1986        PMID： 2941916     DOI： 10.1007/bf00708248

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histopathol        ISSN： 0174-7398


  11 in total

1.  Granulocytopenia in histiocytic necrotizing lymphadenitis without granulocytic infiltration: decreased CFU-C and an inhibitory effect of the serum.

Authors:  Y Naito; S Okamura; Y Iwata; Y Niho; T Otsuka; Y Yamano; Y Hirota
Journal:  Nihon Ketsueki Gakkai Zasshi       Date:  1985-07

2.  Deficient natural killer (NK) cell activity in paroxysmal nocturnal haemoglobinuria (PNH).

Authors:  Y Yoda; T Abe; K Mitamura; K Saito; K Kawada; Y Onozawa; Y Adachi; T Nomura
Journal:  Br J Haematol       Date:  1982-12       Impact factor: 6.998

3.  Necrotising lymphadenitis without granulocytic infiltration (Kikuchi's disease).

Authors:  M H Ali; L W Horton
Journal:  J Clin Pathol       Date:  1985-11       Impact factor: 3.411

4.  Histiocytic necrotizing lymphadenitis without granulocytic infiltration.

Authors:  S Pileri; M Kikuchi; D Helbron; K Lennert
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1982

5.  Necrotizing lymphadenitis. A study of 30 cases.

Authors:  R R Turner; J Martin; R F Dorfman
Journal:  Am J Surg Pathol       Date:  1983-03       Impact factor: 6.394

6.  Necrotizing lymphadenitis: possible acute toxoplasmic infection.

Authors:  M Kikuchi; T Yoshizumi; H Nakamura
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1977-11-25

7.  Immunohistology and aetiology of histiocytic necrotizing lymphadenitis. Report of three instructive cases.

Authors:  A C Feller; K Lennert; H Stein; H D Bruhn; H H Wuthe
Journal:  Histopathology       Date:  1983-11       Impact factor: 5.087

8.  Histiocytic necrotizing lymphadenitis. An ultrastructural study in comparison with other types of lymphadenitis.

Authors:  T Eimoto; M Kikuchi; T Mitsui
Journal:  Acta Pathol Jpn       Date:  1983-09

9.  Subacute necrotizing lymphadenitis --a clinicopathologic study.

Authors:  T Fujimori; K Shioda; E B Sussman; M Miura; I Katayama
Journal:  Acta Pathol Jpn       Date:  1981-09

10.  Immune cell populations in cutaneous delayed-type hypersensitivity.

Authors:  J L Platt; B W Grant; A A Eddy; A F Michael
Journal:  J Exp Med       Date:  1983-10-01       Impact factor: 14.307
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  6 in total

1.  A case of histiocytic necrotizing lymphadenitis with bone marrow and skin involvement.

Authors:  Y Sumiyoshi; M Kikuchi; K Ohshima; Y Masuda; M Takeshita; T Okamura
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

2.  Immune status of children on continuous ambulatory peritoneal dialysis.

Authors:  S Hisano; C Miyazaki; K Hatae; Y Kaku; I Yamane; K Ueda; S Okamua
Journal:  Pediatr Nephrol       Date:  1992-03       Impact factor: 3.714

3.  Virus-associated haemophagocytic syndrome with Epstein-Barr virus infection.

Authors:  K Ohshima; M Kikuchi; F Eguchi; S Kobari; H Tasaka
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991

4.  Analysis of herpesvirus genomes in Kikuchi's disease.

Authors:  Y Sumiyoshi; M Kikuchi; T Minematu; K Ohshima; M Takeshita; Y Minamishima
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064

5.  Necrotizing lymphadenitis: a clinicopathological and immunohistochemical study of four familial cases and five recurrent cases.

Authors:  S Asano; Y Akaike; T Muramatsu; H Wakasa; H Yoshida; R Kondou; M Kojima; T Jyoushita
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991

6.  Necrotizing lymphadenitis (NEL) is a systemic disease characterized by blastic transformation of CD8+ cells and apoptosis of CD4+ cells.

Authors:  Shigeyuki Asano; Kikuo Mori; Kazuki Yamazaki; Tetsutaro Sata; Atsushi Kurata; Yuko Sato; Hajime Odajima; Yasushi Akaike; Haruki Wakasa; Masaru Kojima
Journal:  Virchows Arch       Date:  2013-11-30       Impact factor: 4.535
  6 in total

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