Literature DB >> 1661049

Virus-associated haemophagocytic syndrome with Epstein-Barr virus infection.

K Ohshima1, M Kikuchi, F Eguchi, S Kobari, H Tasaka.   

Abstract

The clinical and histological findings of a 10-year-old girl with virus-associated haemophagocytic syndrome are presented. The serum levels of Epstein-Barr viral antigens were elevated. Epstein-Barr virus (EBV) genome was detected by polymerase chain reaction in bone marrow and lymph node specimens. Histologically, haemophagocytic histiocytes were present in bone marrow, and areas of non-suppurative necrosis were present in lymph nodes, where silver grain deposition of the EBV genome was demonstrated by in situ hybridization.

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Year:  1991        PMID: 1661049     DOI: 10.1007/bf01650682

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histopathol        ISSN: 0174-7398


  23 in total

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