Literature DB >> 29415853

Expected and actual fentanyl exposure among persons seeking opioid withdrawal management.

Shannon R Kenney1, Bradley J Anderson2, Micah T Conti3, Genie L Bailey4, Michael D Stein5.   

Abstract

OBJECTIVE: Fentanyl-contaminated opioid supplies have led to rising overdose fatalities in recent years. We compared beliefs, behaviors, and risk perceptions related to fentanyl with actual toxicology reports among people who used opioids.
METHOD: Participants (n=231) were patients undergoing short-term inpatient opioid withdrawal management in Fall River, Massachusetts. We compared persons testing positive and negative for fentanyl on urine toxicological testing at program entry.
RESULTS: Nearly all (95.7%) participants believed that fentanyl increases risk for overdose/death, and 86.6% of participants tested positive for fentanyl. Positive fentanyl toxicology test results were associated with lower educational attainment, history of injection drug use, and self-reported lifetime use of fentanyl. Of those reporting they had never been exposed to fentanyl (intentionally or unintentionally) (n=33), two-thirds tested positive for fentanyl; among those believing their tests would be negative (n=49), 71.4% tested positive for fentanyl. Heroin use was associated with fentanyl exposure; persons who reported past month heroin use (n=213) were more likely to test positive for fentanyl (91.1%) than persons using non-heroin opioids (n=18; 33.3%).
CONCLUSIONS: Nearly nine in ten participants tested positive for fentanyl, including participants who anticipated their tests would be negative. Leveraging toxicology results in opioid withdrawal settings may be helpful in educating patients about fentanyl exposure and risks.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Fentanyl exposure; Heroin; Opioids; Risk perceptions; Treatment

Mesh:

Substances:

Year:  2018        PMID: 29415853      PMCID: PMC5808984          DOI: 10.1016/j.jsat.2018.01.005

Source DB:  PubMed          Journal:  J Subst Abuse Treat        ISSN: 0740-5472


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Journal:  J Subst Abuse Treat       Date:  2017-01-14

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7.  Deaths Involving Fentanyl, Fentanyl Analogs, and U-47700 - 10 States, July-December 2016.

Authors:  Julie K O'Donnell; John Halpin; Christine L Mattson; Bruce A Goldberger; R Matthew Gladden
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8.  Exposure to fentanyl-contaminated heroin and overdose risk among illicit opioid users in Rhode Island: A mixed methods study.

Authors:  Jennifer J Carroll; Brandon D L Marshall; Josiah D Rich; Traci C Green
Journal:  Int J Drug Policy       Date:  2017-06-01

9.  Why the FUSS (Fentanyl Urine Screen Study)? A cross-sectional survey to characterize an emerging threat to people who use drugs in British Columbia, Canada.

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10.  Factors associated with knowledge of a Good Samaritan Law among young adults who use prescription opioids non-medically.

Authors:  Tristan I Evans; Scott E Hadland; Melissa A Clark; Traci C Green; Brandon D L Marshall
Journal:  Harm Reduct J       Date:  2016-07-26
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Authors:  Sean T Allen; Rebecca Hamilton White; Allison O'Rourke; Suzanne M Grieb; Michael E Kilkenny; Susan G Sherman
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3.  Street fentanyl use: Experiences, preferences, and concordance between self-reports and urine toxicology.

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4.  Fentanyl exposure among patients seeking opioid treatment.

Authors:  Taylor A Ochalek; Maria A Parker; Stephen T Higgins; Stacey C Sigmon
Journal:  J Subst Abuse Treat       Date:  2018-10-17

5.  Elevated prevalence of self-reported unintentional exposure to fentanyl among women who use drugs in a Canadian setting: A cross-sectional analysis.

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6.  Understanding the increase in opioid overdoses in New Hampshire: A rapid epidemiologic assessment.

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Journal:  Drug Alcohol Depend       Date:  2020-02-07       Impact factor: 4.492

7.  Perceptions about fentanyl-adulterated heroin and overdose risk reduction behaviors among persons seeking treatment for heroin use.

Authors:  Michael D Stein; Shannon R Kenney; Bradley J Anderson; Genie L Bailey
Journal:  J Subst Abuse Treat       Date:  2019-07-13

8.  Testing hair for fentanyl exposure: a method to inform harm reduction behavior among individuals who use heroin.

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10.  Fentanyl exposure and preferences among individuals starting treatment for opioid use disorder.

Authors:  Jan Gryczynski; Helen Nichols; Robert P Schwartz; Shannon Gwin Mitchell; Paulette Hill; Kim Wireman
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