Literature DB >> 2941138

Immunologic alterations in xeroderma pigmentosum patients.

A J Wysenbeek, H Weiss, M Duczyminer-Kahana, M H Grunwald, A I Pick.   

Abstract

Nine xeroderma pigmentosum (XP) patients were investigated. In comparison to a normal control group the XP patients had a reduced OKT-4 lymphocyte subpopulation, reduced response of lymphocytes to phytohemagglutinin in autologous serum, and diminished delayed hypersensitivity skin reaction. The possible contribution of ultraviolet irradiation to the observed immunologic alterations, and the link of these alterations to the susceptibility of patients for malignant transformation is discussed.

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Year:  1986        PMID: 2941138     DOI: 10.1002/1097-0142(19860715)58:2<219::aid-cncr2820580203>3.0.co;2-a

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  5 in total

1.  Down syndrome: is it really characterized by precocious immunosenescence?

Authors:  Maaike Aa Kusters; Ruud Hj Verstegen; Esther de Vries
Journal:  Aging Dis       Date:  2011-12-02       Impact factor: 6.745

2.  Impaired interferon production and natural killer cell activation in patients with the skin cancer-prone disorder, xeroderma pigmentosum.

Authors:  A A Gaspari; T A Fleisher; K H Kraemer
Journal:  J Clin Invest       Date:  1993-09       Impact factor: 14.808

3.  Immune defects in families and patients with xeroderma pigmentosum and trichothiodystrophy.

Authors:  E Mariani; A Facchini; M C Honorati; E Lalli; E Berardesca; P Ghetti; S Marinoni; F Nuzzo; G C Astaldi Ricotti; M Stefanini
Journal:  Clin Exp Immunol       Date:  1992-06       Impact factor: 4.330

Review 4.  Photoimmunology.

Authors:  Craig A Elmets; Cather M Cala; Hui Xu
Journal:  Dermatol Clin       Date:  2014-05-05       Impact factor: 3.478

5.  Inflammatory landscape in Xeroderma pigmentosum patients with cutaneous melanoma.

Authors:  Asma Chikhaoui; Meriem Jones; Tadeja Režen; Melika Ben Ahmed; Chokri Naouali; Radovan Komel; Mohamed Zghal; Samir Boubaker; Sonia Abdelhak; Houda Yacoub-Youssef
Journal:  Sci Rep       Date:  2022-08-16       Impact factor: 4.996

  5 in total

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