| Literature DB >> 29409772 |
Ruyu Yao1, Chao Huang2, Xingfu Chen3, Zhongqiong Yin2, Yuping Fu2, Lixia Li2, Bin Feng4, Xu Song2, Changliang He2, Guizhou Yue5, Bo Jing2, Cheng Lv2, Gang Su2, Gang Ye2, Yuanfeng Zou6.
Abstract
Purification, characterization and biological activities of polysaccharides from Lycium barbarum pedicel were investigated in this study. Two polysaccharides, PLBP-I-I and PLBP-II-I, were obtained from water extracts by anion exchange chromatography and gel filtration. Structural elucidation based on IR, 1H NMR, and 13C NMR spectra indicated that these two fractions were typical pectic polysaccharides, with homogalacturonan and rhamnogalacturonan type I regions and arabinogalactan side chains, and some of the galacturonic acid units were methyl esterified. Both fractions exhibited potent complement fixating activity and pro-antioxidant defense capacity, and those two fractions showed different activities. The higher complement fixation activity was obtained in fraction PLBP-I-I, while the higher pro-antioxidant defense capacity was obtained in fraction PLBP-II-I, which may be due to the structural differences between those two fractions. Thus, the pedicel of L. barbarum could be used as a potential source for natural immunomodulator and antioxidant.Entities:
Keywords: Immunomodulating activity; Lycium barbarum pedicel; Polysaccharides
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Year: 2018 PMID： 29409772 DOI： 10.1016/j.ijbiomac.2018.01.207
Source DB: PubMed Journal: Int J Biol Macromol ISSN： 0141-8130 Impact factor: 6.953