Literature DB >> 29406813

Reading cytosine modifications within chromatin.

Elise A Mahé1, Thierry Madigou1, Gilles Salbert1.   

Abstract

Zinc-finger and homeodomain transcription factors have been shown in vitro to bind to recognition motifs containing a methylated CpG. However, accessing these motifs in vivo might be seriously impeded by the inclusion of DNA in nucleosomes and by the condensed structure adopted by chromatin formed on methylated DNA. Here, we discuss how oxidation of 5-methylcytosine into 5-hydroxymethylcytosine could provide the initial destabilizing clue for such transcription factors to get access to nucleosomal DNA and read epigenetic information.

Entities:  

Keywords:  5-hydroxymethylcytosine chromatin; 5-methylcytosine; DNA methylation; ten eleven translocation; transcription factors

Mesh：

Substances：

Year:  2018        PMID： 29406813      PMCID： PMC6104689          DOI： 10.1080/21541264.2017.1406435

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  51 in total

1.  The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor.

Authors:  A Prokhortchouk; B Hendrich; H Jørgensen; A Ruzov; M Wilm; G Georgiev; A Bird; E Prokhortchouk
Journal:  Genes Dev       Date:  2001-07-01       Impact factor: 11.361

2.  The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation.

Authors:  Francois Fuks; Paul J Hurd; Daniel Wolf; Xinsheng Nan; Adrian P Bird; Tony Kouzarides
Journal:  J Biol Chem       Date:  2002-11-09       Impact factor: 5.157

3.  Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior.

Authors:  Nicole A LaRonde-LeBlanc; Cynthia Wolberger
Journal:  Genes Dev       Date:  2003-08-15       Impact factor: 11.361

4.  DNA-binding factors shape the mouse methylome at distal regulatory regions.

Authors:  Michael B Stadler; Rabih Murr; Lukas Burger; Robert Ivanek; Florian Lienert; Anne Schöler; Erik van Nimwegen; Christiane Wirbelauer; Edward J Oakeley; Dimos Gaidatzis; Vijay K Tiwari; Dirk Schübeler
Journal:  Nature       Date:  2011-12-14       Impact factor: 49.962

5.  Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.

Authors:  Yu-Fei He; Bin-Zhong Li; Zheng Li; Peng Liu; Yang Wang; Qingyu Tang; Jianping Ding; Yingying Jia; Zhangcheng Chen; Lin Li; Yan Sun; Xiuxue Li; Qing Dai; Chun-Xiao Song; Kangling Zhang; Chuan He; Guo-Liang Xu
Journal:  Science       Date:  2011-08-04       Impact factor: 47.728

Review 6.  Effects of DNA methylation on DNA-binding proteins and gene expression.

Authors:  P H Tate; A P Bird
Journal:  Curr Opin Genet Dev       Date:  1993-04       Impact factor: 5.578

7.  Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers.

Authors:  Aurélien A Sérandour; Stéphane Avner; Frédérik Oger; Maud Bizot; Frédéric Percevault; Céline Lucchetti-Miganeh; Gaëlle Palierne; Céline Gheeraert; Frédérique Barloy-Hubler; Christine Le Péron; Thierry Madigou; Emmanuelle Durand; Philippe Froguel; Bart Staels; Philippe Lefebvre; Raphaël Métivier; Jérôme Eeckhoute; Gilles Salbert
Journal:  Nucleic Acids Res       Date:  2012-06-22       Impact factor: 16.971

8.  Cytosine modifications modulate the chromatin architecture of transcriptional enhancers.

Authors:  Elise A Mahé; Thierry Madigou; Aurélien A Sérandour; Maud Bizot; Stéphane Avner; Frédéric Chalmel; Gaëlle Palierne; Raphaël Métivier; Gilles Salbert
Journal:  Genome Res       Date:  2017-04-10       Impact factor: 9.043

9.  The role of DNA shape in protein-DNA recognition.

Authors:  Remo Rohs; Sean M West; Alona Sosinsky; Peng Liu; Richard S Mann; Barry Honig
Journal:  Nature       Date:  2009-10-29       Impact factor: 49.962

10.  Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity.

Authors:  Sergei Khrapunov; Christopher Warren; Huiyong Cheng; Esther R Berko; John M Greally; Michael Brenowitz
Journal:  Biochemistry       Date:  2014-05-23       Impact factor: 3.162
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  4 in total

1.  Whole-Genome Differentially Hydroxymethylated DNA Regions among Twins Discordant for Cardiovascular Death.

Authors:  Jun Dai; Ming Leung; Weihua Guan; Han-Tian Guo; Ruth E Krasnow; Thomas J Wang; Wael El-Rifai; Zhongming Zhao; Terry Reed
Journal:  Genes (Basel)       Date:  2021-07-29       Impact factor: 4.096

2.  Development of a new promoter to avoid the silencing of genes in the production of recombinant antibodies in chinese hamster ovary cells.

Authors:  Roberto A Zúñiga; Matías Gutiérrez-González; Norberto Collazo; Pablo Hérnan Sotelo; Carolina H Ribeiro; Claudia Altamirano; Carmen Lorenzo; Juan Carlos Aguillón; María Carmen Molina
Journal:  J Biol Eng       Date:  2019-06-28       Impact factor: 4.355

Review 3.  DNA hypermethylation in disease: mechanisms and clinical relevance.

Authors:  Melanie Ehrlich
Journal:  Epigenetics       Date:  2019-07-08       Impact factor: 4.528

4.  TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis.

Authors:  Audrey Laurent; Thierry Madigou; Maud Bizot; Marion Turpin; Gaëlle Palierne; Elise Mahé; Sarah Guimard; Raphaël Métivier; Stéphane Avner; Christine Le Péron; Gilles Salbert
Journal:  Life Sci Alliance       Date:  2022-03-29
  4 in total

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