Literature DB >> 29404390

Switching from TNF-induced inflammation to death signaling.

Qing Xu1, Swati Choksi1, Zhengang Liu1.   

Abstract

TNFR1-mediated cell signaling involves complex molecular pathways leading to inflammation and death. Cytosolic RARγ plays a pivotal role in converting TNF-induced inflammatory responses to RIP1 initiated cell death and this finely regulated function of RARγ serves as a checkpoint to engage death pathways in response to TNF.

Entities:  

Keywords:  Cell death; Mechanisms of oncogenesis and tumor progression; Mechanisms of resistance to therapy; RARg; RIP1; inflammatory signaling; necroptosis

Year:  2017        PMID： 29404390      PMCID： PMC5791850          DOI： 10.1080/23723556.2017.1392402

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  9 in total

1.  Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes.

Authors:  Olivier Micheau; Jürg Tschopp
Journal:  Cell       Date:  2003-07-25       Impact factor: 41.582

Review 2.  Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death.

Authors:  Dimitry Ofengeim; Junying Yuan
Journal:  Nat Rev Mol Cell Biol       Date:  2013-10-16       Impact factor: 94.444

Review 3.  Regulation of tumour necrosis factor signalling: live or let die.

Authors:  Dirk Brenner; Heiko Blaser; Tak W Mak
Journal:  Nat Rev Immunol       Date:  2015-06       Impact factor: 53.106

Review 4.  Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

Authors:  P Kastner; M Mark; P Chambon
Journal:  Cell       Date:  1995-12-15       Impact factor: 41.582

5.  Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.

Authors:  Zhenyu Cai; Siriporn Jitkaew; Jie Zhao; Hsueh-Cheng Chiang; Swati Choksi; Jie Liu; Yvona Ward; Ling-Gang Wu; Zheng-Gang Liu
Journal:  Nat Cell Biol       Date:  2013-12-08       Impact factor: 28.824

Review 6.  TNF-R1 signaling: a beautiful pathway.

Authors:  Guoqing Chen; David V Goeddel
Journal:  Science       Date:  2002-05-31       Impact factor: 47.728

7.  The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors.

Authors:  Yelena L Pobezinskaya; You-Sun Kim; Swati Choksi; Michael J Morgan; Tao Li; Chengyu Liu; Zhenggang Liu
Journal:  Nat Immunol       Date:  2008-07-20       Impact factor: 25.606

8.  Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha.

Authors:  Sudan He; Lai Wang; Lin Miao; Tao Wang; Fenghe Du; Liping Zhao; Xiaodong Wang
Journal:  Cell       Date:  2009-06-12       Impact factor: 41.582

9.  The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited.

Authors:  Qing Xu; Siriporn Jitkaew; Swati Choksi; Chamila Kadigamuwa; Jianhui Qu; Moran Choe; Jonathan Jang; Chengyu Liu; Zheng-Gang Liu
Journal:  Nat Commun       Date:  2017-09-04       Impact factor: 14.919
  9 in total
  3 in total

Review 1.  The resurrection of RIP kinase 1 as an early cell death checkpoint regulator-a potential target for therapy in the necroptosis era.

Authors:  Eunjin Ju; Kyeong Ah Park; Han-Ming Shen; Gang Min Hur
Journal:  Exp Mol Med       Date:  2022-09-28       Impact factor: 12.153

2.  TNFα promotes glioblastoma A172 cell mitochondrial apoptosis via augmenting mitochondrial fission and repression of MAPK-ERK-YAP signaling pathways.

Authors:  Changyu Lu; Xiaolei Chen; Qun Wang; Xinghua Xu; Bainan Xu
Journal:  Onco Targets Ther       Date:  2018-10-18       Impact factor: 4.147

Review 3.  Neuroprotective Approach of Anti-Cancer Microtubule Stabilizers Against Tauopathy Associated Dementia: Current Status of Clinical and Preclinical Findings.

Authors:  Pallavi Duggal; Sidharth Mehan
Journal:  J Alzheimers Dis Rep       Date:  2019-07-02
  3 in total

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