Literature DB >> 29398402

Pulmonary Comorbidity in Lung Cancer.

Feixiong Cheng1, Joseph Loscalzo2.   

Abstract

Pulmonary hypertension (PH) is caused by many disorders that affect the pulmonary vasculature. A recent study has provided evidence that pulmonary vascular remodeling and PH can be observed in lung cancer, and this may be associated with tumor cell-immune cell inflammatory crosstalk. These findings highlight the pressing need to understand better and manage pulmonary vascular comorbidities in lung cancer.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  cardio-oncology; disease comorbidity; inflammatory; lung cancer; pulmonary hypertension

Mesh：

Year:  2018        PMID： 29398402      PMCID： PMC5937923          DOI： 10.1016/j.molmed.2018.01.005

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  10 in total

1.  Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension.

Authors:  Felix Beuschlein; Sheerazed Boulkroun; Andrea Osswald; Thomas Wieland; Hang N Nielsen; Urs D Lichtenauer; David Penton; Vivien R Schack; Laurence Amar; Evelyn Fischer; Anett Walther; Philipp Tauber; Thomas Schwarzmayr; Susanne Diener; Elisabeth Graf; Bruno Allolio; Benoit Samson-Couterie; Arndt Benecke; Marcus Quinkler; Francesco Fallo; Pierre-Francois Plouin; Franco Mantero; Thomas Meitinger; Paolo Mulatero; Xavier Jeunemaitre; Richard Warth; Bente Vilsen; Maria-Christina Zennaro; Tim M Strom; Martin Reincke
Journal:  Nat Genet       Date:  2013-02-17       Impact factor: 38.330

2.  Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk.

Authors:  Soni Savai Pullamsetti; Baktybek Kojonazarov; Samantha Storn; Henning Gall; Ylia Salazar; Janine Wolf; Andreas Weigert; Nefertiti El-Nikhely; Hossein Ardeschir Ghofrani; Gabriele A Krombach; Ludger Fink; Stefan Gattenlöhner; Ulf R Rapp; Ralph Theo Schermuly; Friedrich Grimminger; Werner Seeger; Rajkumar Savai
Journal:  Sci Transl Med       Date:  2017-11-15       Impact factor: 17.956

3.  Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension.

Authors:  Micheala A Aldred; Suzy A Comhair; Marileila Varella-Garcia; Kewal Asosingh; Weiling Xu; George P Noon; Patricia A Thistlethwaite; Rubin M Tuder; Serpil C Erzurum; Mark W Geraci; Christopher D Coldren
Journal:  Am J Respir Crit Care Med       Date:  2010-06-25       Impact factor: 21.405

4.  Disease networks. Uncovering disease-disease relationships through the incomplete interactome.

Authors:  Jörg Menche; Amitabh Sharma; Maksim Kitsak; Susan Dina Ghiassian; Marc Vidal; Joseph Loscalzo; Albert-László Barabási
Journal:  Science       Date:  2015-02-20       Impact factor: 47.728

5.  Cancer Statistics, 2017.

Authors:  Rebecca L Siegel; Kimberly D Miller; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2017-01-05       Impact factor: 508.702

6.  Hypoxia-Mediated Increases in L-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress.

Authors:  William M Oldham; Clary B Clish; Yi Yang; Joseph Loscalzo
Journal:  Cell Metab       Date:  2015-07-23       Impact factor: 27.287

7.  Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients.

Authors:  Evangelos D Michelakis; Vikram Gurtu; Linda Webster; Gareth Barnes; Geoffrey Watson; Luke Howard; John Cupitt; Ian Paterson; Richard B Thompson; Kelvin Chow; Declan P O'Regan; Lan Zhao; John Wharton; David G Kiely; Adam Kinnaird; Aristeidis E Boukouris; Chris White; Jayan Nagendran; Darren H Freed; Stephen J Wort; J Simon R Gibbs; Martin R Wilkins
Journal:  Sci Transl Med       Date:  2017-10-25       Impact factor: 17.956

8.  SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents.

Authors:  Yuzheng Zhao; Qingxun Hu; Feixiong Cheng; Ni Su; Aoxue Wang; Yejun Zou; Hanyang Hu; Xianjun Chen; Hai-Meng Zhou; Xinzhi Huang; Kai Yang; Qian Zhu; Xue Wang; Jing Yi; Linyong Zhu; Xuhong Qian; Lixin Chen; Yun Tang; Joseph Loscalzo; Yi Yang
Journal:  Cell Metab       Date:  2015-05-05       Impact factor: 27.287

9.  Endophenotype Network Models: Common Core of Complex Diseases.

Authors:  Susan Dina Ghiassian; Jörg Menche; Daniel I Chasman; Franco Giulianini; Ruisheng Wang; Piero Ricchiuto; Masanori Aikawa; Hiroshi Iwata; Christian Müller; Tania Zeller; Amitabh Sharma; Philipp Wild; Karl Lackner; Sasha Singh; Paul M Ridker; Stefan Blankenberg; Albert-László Barabási; Joseph Loscalzo
Journal:  Sci Rep       Date:  2016-06-09       Impact factor: 4.379

10.  Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.

Authors:  Siddhartha Jaiswal; Pradeep Natarajan; Alexander J Silver; Christopher J Gibson; Alexander G Bick; Eugenia Shvartz; Marie McConkey; Namrata Gupta; Stacey Gabriel; Diego Ardissino; Usman Baber; Roxana Mehran; Valentin Fuster; John Danesh; Philippe Frossard; Danish Saleheen; Olle Melander; Galina K Sukhova; Donna Neuberg; Peter Libby; Sekar Kathiresan; Benjamin L Ebert
Journal:  N Engl J Med       Date:  2017-06-21       Impact factor: 91.245
  10 in total
  3 in total

Review 1.  Epigenetic Inheritance Underlying Pulmonary Arterial Hypertension.

Authors:  Claudio Napoli; Giuditta Benincasa; Joseph Loscalzo
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-04       Impact factor: 8.311

2.  KRAS Activating Signaling Triggers Arteriovenous Malformations.

Authors:  Feixiong Cheng; Ruth Nussinov
Journal:  Trends Biochem Sci       Date:  2018-05-07       Impact factor: 13.807

3.  A network-based approach to uncover microRNA-mediated disease comorbidities and potential pathobiological implications.

Authors:  Shuting Jin; Xiangxiang Zeng; Jiansong Fang; Jiawei Lin; Stephen Y Chan; Serpil C Erzurum; Feixiong Cheng
Journal:  NPJ Syst Biol Appl       Date:  2019-11-13
  3 in total

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