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Literature DB >> 2939198

Striatal dopamine and homovanillic acid in Huntington's disease.

Abstract

Using tissue taken post mortem from patients with neuropathologically confirmed Huntington's disease and a series of appropriate control cases, GABA, dopamine and homovanillic acid were measured in the caudate nucleus and the putamen. The previously reported loss of GABA in Huntington's disease was confirmed, while no change in dopamine concentrations and a loss of homovanillic acid in these striatal regions were observed. This loss could not be explained on the basis of agonal state or previous drug treatment.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1986 PMID： 2939198 DOI： 10.1007/bf01256491

Source DB: PubMed Journal: J Neural Transm Impact factor: 3.575

9 in total

1. CSF homovanillic acid: an index of dopaminergic activity.

Authors: G Curzon
Journal: Adv Neurol Date: 1975

2. A FURTHER STUDY OF THE DISTRIBUTION OF GAMMA-AMINOBUTYRIC ACID BETWEEN EXCITATORY AND INHIBITORY AXONS OF THE LOBSTER.

Authors: E A KRAVITZ; D D POTTER
Journal: J Neurochem Date: 1965-04 Impact factor: 5.372

3. Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain.

Authors: T L Perry; S Hansen; M Kloster
Journal: N Engl J Med Date: 1973-02-15 Impact factor: 91.245

4. Amine metabolites in the cerbrospinal fluid in Huntington's chorea.

Authors: G Curzon; J Gumpert; D Sharpe
Journal: J Neurol Neurosurg Psychiatry Date: 1972-08 Impact factor: 10.154

5. Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia.

Authors: E D Bird; L L Iversen
Journal: Brain Date: 1974-09 Impact factor: 13.501

6. An analysis of factors influencing measurements of dopamine, noradrenaline, glutamate decarboxylase and choline acetylase in human post-mortem brain tissue.

Authors: E G Spokes
Journal: Brain Date: 1979-06 Impact factor: 13.501

7. Monoamine mechanisms in chronic schizophrenia: post-mortem neurochemical findings.

Authors: T J Crow; H F Baker; A J Cross; M H Joseph; R Lofthouse; A Longden; F Owen; G J Riley; V Glover; W S Killpack
Journal: Br J Psychiatry Date: 1979-03 Impact factor: 9.319

8. Neurochemical alterations in Huntington's chorea: a study of post-mortem brain tissue.

Authors: E G Spokes
Journal: Brain Date: 1980-03 Impact factor: 13.501

9. Huntington chorea is not associated with hyperactivity of nigrostriatal dopaminergic neurons: studies in postmortem tissues and in rats with kainic acid lesions.

Authors: E Melamed; F Hefti; E D Bird
Journal: Neurology Date: 1982-06 Impact factor: 9.910

9 in total

14 in total

10. Components of the endocannabinoid and dopamine systems are dysregulated in Huntington's disease: analysis of publicly available microarray datasets.

Authors: Robert B Laprairie; Amina M Bagher; Sophie V Precious; Eileen M Denovan-Wright
Journal: Pharmacol Res Perspect Date: 2015-01-05

Striatal dopamine and homovanillic acid in Huntington's disease.

1. CSF homovanillic acid: an index of dopaminergic activity.

2. A FURTHER STUDY OF THE DISTRIBUTION OF GAMMA-AMINOBUTYRIC ACID BETWEEN EXCITATORY AND INHIBITORY AXONS OF THE LOBSTER.

3. Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain.

4. Amine metabolites in the cerbrospinal fluid in Huntington's chorea.

5. Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia.

6. An analysis of factors influencing measurements of dopamine, noradrenaline, glutamate decarboxylase and choline acetylase in human post-mortem brain tissue.

7. Monoamine mechanisms in chronic schizophrenia: post-mortem neurochemical findings.

8. Neurochemical alterations in Huntington's chorea: a study of post-mortem brain tissue.

9. Huntington chorea is not associated with hyperactivity of nigrostriatal dopaminergic neurons: studies in postmortem tissues and in rats with kainic acid lesions.

Review 1. Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man.

Review 2. Huntington's disease: the coming of age.

3. Neocortical neurotransmitter markers in Huntington's disease.

Review 4. Genetics and neuropathology of Huntington's disease.

5. Pallidal GABA and chorea in Huntington's disease.

6. Plasma homovanillic acid and prolactin in Huntington's disease.

7. HPLC analysis of somatostatin related peptides in putamen of Huntington's disease patients.

Review 8. Dopamine-derived alkaloids in alcoholism and in Parkinson's and Huntington's diseases.

9. Error processing in Huntington's disease.

10. Components of the endocannabinoid and dopamine systems are dysregulated in Huntington's disease: analysis of publicly available microarray datasets.