Literature DB >> 29388991

In situ formation of large pore silica-MnO2 nanocomposites with H+/H2O2 sensitivity for O2-elevated photodynamic therapy and potential MR imaging.

Zhimei He1, Yan Xiao1, Jian-Rong Zhang2, Penghui Zhang3, Jun-Jie Zhu1.   

Abstract

A cancer cell-specific, endogenous H+/H2O2-activated, and O2 self-sufficient nanocomposite is engineered and characterized. Such NPs, with good biocompatibility and rapid response to intracellular H+/H2O2, have demonstrated improved therapeutic effects in targeted cancer cells and activated MR signals in vitro, providing a promising strategy for effective PDT against tumor hypoxia.

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Year:  2018        PMID： 29388991     DOI： 10.1039/c7cc09532e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Manganese Oxide Nanoparticles As MRI Contrast Agents In Tumor Multimodal Imaging And Therapy.

Authors:  Xiaoxia Cai; Qingxia Zhu; Yun Zeng; Qi Zeng; Xueli Chen; Yonghua Zhan
Journal:  Int J Nanomedicine       Date:  2019-10-21

Review 2.  Fighting Hypoxia to Improve PDT.

Authors:  Ludivine Larue; Bauyrzhan Myrzakhmetov; Amina Ben-Mihoub; Albert Moussaron; Noémie Thomas; Philippe Arnoux; Francis Baros; Régis Vanderesse; Samir Acherar; Céline Frochot
Journal:  Pharmaceuticals (Basel)       Date:  2019-10-30

Review 3.  Smart nanomedicine agents for cancer, triggered by pH, glutathione, H2O2, or H2S.

Authors:  Yaping Li; Lu An; Jiaomin Lin; Qiwei Tian; Shiping Yang
Journal:  Int J Nanomedicine       Date:  2019-07-24

Review 4.  Solutions to the Drawbacks of Photothermal and Photodynamic Cancer Therapy.

Authors:  Xiangyu Deng; Zengwu Shao; Yanli Zhao
Journal:  Adv Sci (Weinh)       Date:  2021-01-05       Impact factor: 16.806

5.  Tumor Microenvironment-triggered Nanosystems as dual-relief Tumor Hypoxia Immunomodulators for enhanced Phototherapy.

Authors:  Zijun Shen; Junfei Xia; Qingming Ma; Wei Zhu; Zhen Gao; Shangcong Han; Yan Liang; Jie Cao; Yong Sun
Journal:  Theranostics       Date:  2020-07-13       Impact factor: 11.556
  5 in total

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