| Literature DB >> 29387459 |
Robert D Adam1, James Shambrook1, Andrew S Flett1.
Abstract
Despite significant advances in heart failure diagnostics and therapy, the prognosis remains poor, with one in three dying within a year of hospital admission. This is at least in part due to the difficulties in risk stratification and personalisation of therapy. The use of left ventricular systolic function as the main arbiter for entrance into clinical trials for drugs and advanced therapy, such as implantable defibrillators, grossly simplifies the complex heterogeneous nature of the syndrome. Cardiovascular magnetic resonance offers a wealth of data to aid in diagnosis and prognostication. The advent of novel cardiovascular magnetic resonance mapping techniques allows us to glimpse some of the pathophysiological mechanisms underpinning heart failure. We review the growing prognostic evidence base using these techniques.Entities:
Keywords: Cardiac magnetic resonance; T1 mapping; T2 techniques; cardiac resynchronisation therapy; extracellular volume; heart failure; implantable cardioverter-defibrillator; late gadolinium enhancement; prognosis; response to therapy
Year: 2017 PMID: 29387459 PMCID: PMC5739890 DOI: 10.15420/cfr.2017:19:1
Source DB: PubMed Journal: Card Fail Rev ISSN: 2057-7540