Bradley D Allen1, Maria L Carr2, Michael Markl3,4, Michael O Zenge5, Michaela Schmidt5, Mariappan S Nadar6, Bruce Spottiswoode7, Jeremy D Collins3, James C Carr3. 1. Department of Radiology, Northwestern University, 737 N. Michigan Ave, Suite 1600, Chicago, IL, 60611, USA. bdallen@northwestern.edu. 2. Northshore University Health System, Evanston, IL, USA. 3. Department of Radiology, Northwestern University, 737 N. Michigan Ave, Suite 1600, Chicago, IL, 60611, USA. 4. Department of Biomedical Engineering, Northwestern University, Chicago, IL, USA. 5. Siemens Healthcare GmbH, Erlangen, Germany. 6. Siemens Healthineers, Siemens Healthcare, Princeton, NJ, USA. 7. MR Collaborations, Siemens Medical Solutions USA Inc, Malvern, PA, USA.
Abstract
OBJECTIVES: To compare accelerated real-time cardiac MRI (CMR) using sparse spatial and temporal undersampling and non-linear iterative SENSE reconstruction (RT IS SENSE) with real-time CMR (RT) and segmented CMR (SEG) in a cohort that included atrial fibrillation (AF) patients. METHODS: We evaluated 27 subjects, including 11 AF patients, by acquiring steady-state free precession cine images covering the left ventricle (LV) at 1.5 T with SEG (acceleration factor 2, TR 42 ms, 1.8 × 1.8 × 6 mm3), RT (acceleration factor 3, TR 62 ms, 3.0 × 3.0 × 7 mm3), and RT IS SENSE (acceleration factor 9.9-12, TR 42 ms, 2.0 × 2.0 × 7 mm3). We performed quantitative LV functional analysis in sinus rhythm (SR) patients and qualitatively scored image quality, noise and artefact using a 5-point Likert scale in the complete cohort and AF and SR subgroups. RESULTS: There was no difference between LV functional parameters between acquisitions in SR patients. RT IS SENSE short-axis image quality was superior to SEG (4.5 ± 0.6 vs. 3.9 ± 1.1, p = 0.007) and RT (3.8 ± 0.4, p = 0.003). There was reduced artefact in RT IS SENSE compared to SEG (4.4 ± 0.6 vs. 3.8 ± 1.2, p = 0.04), driven by arrhythmia performance. RT IS SENSE short-axis image quality was superior to SEG (4.6 ± 0.5 vs. 3.1 ± 1.0, p < 0.001) in the AF subgroup. CONCLUSION: Accelerated real-time CMR with iterative sparse SENSE provides excellent clinical performance, especially in patients with AF. KEY POINTS: • Iterative sparse SENSE significantly accelerates real-time cardiovascular MRI acquisitions. • It provides excellent qualitative and quantitative performance in sinus rhythm patients. • It outperforms standard segmented acquisitions in patients with atrial fibrillation. • It improves the trade-off between temporal and spatial resolution in real-time imaging.
OBJECTIVES: To compare accelerated real-time cardiac MRI (CMR) using sparse spatial and temporal undersampling and non-linear iterative SENSE reconstruction (RT IS SENSE) with real-time CMR (RT) and segmented CMR (SEG) in a cohort that included atrial fibrillation (AF) patients. METHODS: We evaluated 27 subjects, including 11 AFpatients, by acquiring steady-state free precession cine images covering the left ventricle (LV) at 1.5 T with SEG (acceleration factor 2, TR 42 ms, 1.8 × 1.8 × 6 mm3), RT (acceleration factor 3, TR 62 ms, 3.0 × 3.0 × 7 mm3), and RT IS SENSE (acceleration factor 9.9-12, TR 42 ms, 2.0 × 2.0 × 7 mm3). We performed quantitative LV functional analysis in sinus rhythm (SR) patients and qualitatively scored image quality, noise and artefact using a 5-point Likert scale in the complete cohort and AF and SR subgroups. RESULTS: There was no difference between LV functional parameters between acquisitions in SR patients. RT IS SENSE short-axis image quality was superior to SEG (4.5 ± 0.6 vs. 3.9 ± 1.1, p = 0.007) and RT (3.8 ± 0.4, p = 0.003). There was reduced artefact in RT IS SENSE compared to SEG (4.4 ± 0.6 vs. 3.8 ± 1.2, p = 0.04), driven by arrhythmia performance. RT IS SENSE short-axis image quality was superior to SEG (4.6 ± 0.5 vs. 3.1 ± 1.0, p < 0.001) in the AF subgroup. CONCLUSION: Accelerated real-time CMR with iterative sparse SENSE provides excellent clinical performance, especially in patients with AF. KEY POINTS: • Iterative sparse SENSE significantly accelerates real-time cardiovascular MRI acquisitions. • It provides excellent qualitative and quantitative performance in sinus rhythm patients. • It outperforms standard segmented acquisitions in patients with atrial fibrillation. • It improves the trade-off between temporal and spatial resolution in real-time imaging.
Entities:
Keywords:
Acceleration; Atrial fibrillation; Cardiac imaging techniques; Cine MRI; Left ventricular function
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