AIM: The aim of this work was to perform a systematic literature review on the clinical application of rhBMP-2 in bone reconstruction prior to placing implants. MATERIALS AND METHODS: A PUBMED search was made about the subject and nine clinical trials were selected according to strict inclusion criteria. RESULTS: Overall success rates of bone regeneration with rhBMP-2 was 81.4% and success of implants placed was 87.4%. Most frequent adverse events were pain, edema and erythema. CONCLUSION: It was concluded that the treatment with rhBMP-2 foi satisfactory in most cases and the placement of dental implants in the bone regenerated with rhBMP-2 is feasible.
AIM: The aim of this work was to perform a systematic literature review on the clinical application of rhBMP-2 in bone reconstruction prior to placing implants. MATERIALS AND METHODS: A PUBMED search was made about the subject and nine clinical trials were selected according to strict inclusion criteria. RESULTS: Overall success rates of bone regeneration with rhBMP-2 was 81.4% and success of implants placed was 87.4%. Most frequent adverse events were pain, edema and erythema. CONCLUSION: It was concluded that the treatment with rhBMP-2 foi satisfactory in most cases and the placement of dental implants in the bone regenerated with rhBMP-2 is feasible.
Entities:
Keywords:
Bone graft; Bone morphogenetic protein 2; Dental implants; Rehabilitation
Authors: Robert E Marx; Lawrence Armentano; Alberto Olavarria; Juan Samaniego Journal: Int J Oral Maxillofac Implants Date: 2013 Sep-Oct Impact factor: 2.804