| Literature DB >> 29374663 |
Lucie Spreng1, Bernard Favrat2,3, François-Xavier Borruat4, Paul Vaucher3,5.
Abstract
OBJECTIVES: The aim of this study is to quantify the importance of loss of contrast sensitivity (CS) and its relationship to loss of visual acuity (VA), driving restrictions and daytime, on-road driving evaluations in drivers aged 70+.Entities:
Keywords: ageing; automobile driving; contrast sensitivity; vision screening
Mesh:
Year: 2018 PMID: 29374663 PMCID: PMC5829587 DOI: 10.1136/bmjopen-2017-018546
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 2.692
Figure 1Participant flow chart. CS, contrast sensitivity; GarAge, Guarding Aged drivers against accidents project.
Description of the population
| All participants | Both eyes with log(CS) ≥1.5 | Worst eye with log(CS) <1.5 | P value | ||||
| Mean (SD) | Median | Mean (SD) | Median | Mean (SD) | Median | ||
| Age | 76.1 (4.73) | 75.2 (70.8–84.9) | 75.9 (4.64) | 74.9 (70.8–84.9) | 77.0 (5.0) | 75.6 (70.6–88.7) | 0.195 |
| Functional mobility | |||||||
| TUG test (s)† | 9.49 (2.65) | 9.0 (6.8–15.1) | 9.16 (2.32) | 8.8 (6.3–13.1) | 10.7 (3.38) | 10.1 (6.1–16.3) | 0.002 |
| Cognitive state | |||||||
| MoCa (points)‡ | 26.5 (2.63) | 27 (21–30) | 26.5 (2.53) | 27 (21–30) | 26.24 (2.99) | 27 (19–29) | 0.561 |
| Driving | |||||||
| Distance (km)/week | 238 (224) | 200 (60–500) | 234 (239) | 195 (60–500) | 253 (159) | 225 (40–550) | 0.668 |
| Restriction score | 2.3 (2.78) | 1 (0–8) | 1.88 (2.46) | 1 (0–6) | 3.68 (3.45) | 3 (0–12) | <0.001 |
| Vision | |||||||
| VA bilateral§ | 1.02 (0.20) | 1.0 (0.6–1.2) | 1.06 (0.17) | 1.2 (0.8–1.2) | 0.88 (0.24) | 1.0 (0.4–1.2) | <0.001 |
| VA best eye§ | 0.96 (0.22) | 1.0 (0.6–1.2) | 0.99 (0.21) | 1.0 (0.6–1.2) | 0.85 (2.05) | 0.8 (0.6–1.2) | <0.001 |
| VA worst eye§ | 0.72 (0.31) | 0.8 (0.2–1.2) | 0.79 (0.27) | 0.8 (0.4–1.2) | 0.46 (0.31) | 0.4 (0.0–1.0) | <0.001 |
| Visual field¶ | 183 (16) | 180 (160–200) | 185 (14) | 180 (160–200) | 179 (23) | 180 (140–200) | 0.059 |
| CS bilateral** | 1.72 (0.06) | 1.72 (1.6–1.76) | 1.73 (0.04) | 1.74 (1.68–1.76) | 1.66 (0.09) | 1.68 (1.48–1.76) | <0.001 |
| CS best eye** | 1.69 (0.06) | 1.72 (1.56–1.76) | 1.73 (0.04) | 1.74 (1.68–1.76) | 1.66 (0.09) | 1.68 (1.48–1.76) | <0.001 |
| CS worst eye** | 1.57 (0.25) | 1.64 (1.24–1.72) | 1.66 (0.06) | 1.68 (1.52–1.72) | 1.25 (0.38) | 1.44 (0.04–1.48) | <0.001 |
*Student’s t-test comparing groups with or without contrast sensitivity loss.
†If ≥13.5 s: functional mobility difficulties. One person could not do the test and was not assessed.
‡If <26 points: cognitive difficulties.
§In decimal.
¶Visual field in degrees.
**Expressed in log(CS): considered as normal if ≥1.5 log(CS) and restricted if <1.5 log(CS).
CS, contrast sensitivity; MoCa, Montreal Cognitive Assessment; p5, fifth percentile; p95, 95th percentile; TUG, Timed Up-and-Go Test; VA, visual acuity.
Figure 2Driving performances between drivers with normal contrast sensitivity (CS) and those with low CS. (A) On-road driving score ranges from 0 to 8 with higher scores indicating more errors. (B) Driving restriction score ranges from 0 to 20 with higher scores indicating higher levels of restriction.
Advantages of CS over VA for determining driving restriction
| CS | VA | LR test between models | |||
| Adjusted R2† | P value‡ | Adjusted R2† | P value‡ | P value | |
| Both eyes | |||||
| Driving when dark | 0.045 | 0.065 | 0.065 | 0.010 | 0.750 |
| Driving on the highway | 0.095 | 0.609 | 0.097 | 0.438 | 0.999 |
| Driving under foggy conditions | 0.012 | 0.834 | 0.013 | 0.631 | 0.999 |
| Driving on unknown roads | 0.057 | 0.565 | 0.057 | 0.667 | 0.999 |
| Driving in dense traffic | 0.090 | 0.897 | 0.096 | 0.287 | 0.979 |
| Driving restriction score | 0.069 | 0.653 | 0.080 | 0.151 | 0.857 |
| Worst eye | |||||
| Driving when dark | 0.056 | 0.022 | 0.037 | 0.147 | 0.778 |
| Driving on the highway | 0.096 | 0.528 | 0.097 | 0.447 | 0.999 |
| Driving under foggy conditions | 0.083 | 0.001 | 0.018 | 0.312 | 0.090 |
| Driving on unknown roads | 0.066 | 0.185 | 0.061 | 0.354 | 0.988 |
| Driving in dense traffic | 0.103 | 0.122 | 0.094 | 0.390 | 0.943 |
| Driving restriction score | 0.116 | 0.004 | 0.078 | 0.204 | 0.345 |
| Difference between the eyes | |||||
| Driving when dark | 0.050 | 0.032 | 0.044 | 0.448 | 0.985 |
| Driving on the highway | 0.091 | 0.738 | 0.096 | 0.728 | 0.992 |
| Driving under foggy conditions | 0.080 | 0.001 | 0.012 | 0.339 | 0.077 |
| Driving on unknown roads | 0.066 | 0.104 | 0.056 | 0.303 | 0.945 |
| Driving in dense traffic | 0.099 | 0.116 | 0.089 | 0.336 | 0.942 |
| Driving restriction score | 0.113 | 0.004 | 0.072 | 0.271 | 0.292 |
*Best model over worst. P values under 0.05 would mean the test with the highest R2 is significantly better than the other visual test.
†Adjusted R2 for entire model. R2 corresponds to the test’s contribution in explaining restrictions and ranges from 0 to 1.
‡Significance of contribution of visual component.
CS, contrast sensitivity; LR, likelihood ratio; VA, visual acuity.
Advantages of CS over VA for determining on-road driving score (0–3)*
| CS | VA | LR test between models | |||
| R2‡ | P value§ | R2‡ | P value§ | P value | |
| Both eyes | |||||
| On-road driving score (0–3) | 0.0001 | 0.895 | 0.00 | 0.946 | 0.9935 |
| Worst eye | |||||
| On-road driving score (0–3) | 0.0062 | 0.332 | 0.0037 | 0.454 | 0.824 |
| Difference between the eyes | |||||
| On-road driving score (0–3) | 0.059 | 0.411 | 0.057 | 0.568 | 0.999 |
*Excellent=0, Good=1, Moderate=2, Poor=3.
†P values under 0.05 mean that CS improved the prediction of on-road driving scores compared with VA alone.
‡Crude R2 were used instead of adjusted R2 given values were close to 0 and adjustment methods become inadequate. R2 corresponds to the test’s contribution in explaining on-road driving scores and ranges from 0 to 1.
§Significance of contribution of visual component.
CS, contrast sensitivity; LR, likelihood ratio; VA, visual acuity.