Literature DB >> 29374084

Pleiotropic effects of O-glycosylation in colon cancer.

Liping Zhang1, Kelly G Ten Hagen2.   

Abstract

Changes in the O-glycosylation of proteins have long been associated with the development of cancer, but establishing causal relationships between altered glycosylation and cancer progression remains incomplete. In this study, the authors perform comparative analyses of the cellular phenotypes, transcriptional changes, and alterations in the glycoproteome in colon cancer cells that differentially express one glycosyltransferase. Their results provide a wealth of data on which future studies can be based.

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Year:  2018        PMID： 29374084      PMCID： PMC5787807          DOI： 10.1074/jbc.H117.812826

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  10 in total

1.  De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium.

Authors:  Kirstine Lavrsen; Sally Dabelsteen; Sergey Y Vakhrushev; Asha M R Levann; Amalie Dahl Haue; August Dylander; Ulla Mandel; Lars Hansen; Morten Frödin; Eric P Bennett; Hans H Wandall
Journal:  J Biol Chem       Date:  2017-11-29       Impact factor: 5.157

Review 2.  Mucin-type O-glycosylation during development.

Authors:  Duy T Tran; Kelly G Ten Hagen
Journal:  J Biol Chem       Date:  2013-01-17       Impact factor: 5.157

Review 3.  Protein glycosylation in cancer.

Authors:  Sean R Stowell; Tongzhong Ju; Richard D Cummings
Journal:  Annu Rev Pathol       Date:  2015       Impact factor: 23.472

Review 4.  Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.

Authors:  Eric P Bennett; Ulla Mandel; Henrik Clausen; Thomas A Gerken; Timothy A Fritz; Lawrence A Tabak
Journal:  Glycobiology       Date:  2011-12-18       Impact factor: 4.313

5.  Immature truncated O-glycophenotype of cancer directly induces oncogenic features.

Authors:  Prakash Radhakrishnan; Sally Dabelsteen; Frey Brus Madsen; Chiara Francavilla; Katharina L Kopp; Catharina Steentoft; Sergey Y Vakhrushev; Jesper V Olsen; Lars Hansen; Eric P Bennett; Anders Woetmann; Guangliang Yin; Longyun Chen; Haiyan Song; Mads Bak; Ryan A Hlady; Staci L Peters; Rene Opavsky; Christenze Thode; Klaus Qvortrup; Katrine T-B G Schjoldager; Henrik Clausen; Michael A Hollingsworth; Hans H Wandall
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-12       Impact factor: 11.205

6.  O-glycosylation regulates polarized secretion by modulating Tango1 stability.

Authors:  Liping Zhang; Zulfeqhar Ali Syed; Iris van Dijk Härd; Jae-Min Lim; Lance Wells; Kelly G Ten Hagen
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-05       Impact factor: 11.205

7.  Functional genomics reveals genes involved in protein secretion and Golgi organization.

Authors:  Frederic Bard; Laetitia Casano; Arrate Mallabiabarrena; Erin Wallace; Kota Saito; Hitoshi Kitayama; Gianni Guizzunti; Yue Hu; Franz Wendler; Ramanuj Dasgupta; Norbert Perrimon; Vivek Malhotra
Journal:  Nature       Date:  2006-02-02       Impact factor: 49.962

8.  Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.

Authors:  Kishore Guda; Helen Moinova; Jian He; Oliver Jamison; Lakshmeswari Ravi; Leanna Natale; James Lutterbaugh; Earl Lawrence; Susan Lewis; James K V Willson; John B Lowe; Georgia L Wiesner; Giovanni Parmigiani; Jill Barnholtz-Sloan; Dawn W Dawson; Victor E Velculescu; Kenneth W Kinzler; Nikolas Papadopoulos; Bert Vogelstein; Joseph Willis; Thomas A Gerken; Sanford D Markowitz
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-17       Impact factor: 11.205

9.  Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc.

Authors:  Tongzhong Ju; Grainger S Lanneau; Tripti Gautam; Yingchun Wang; Baoyun Xia; Sean R Stowell; Margaret T Willard; Wenyi Wang; Jonathan Y Xia; Rosemary E Zuna; Zoltan Laszik; Doris M Benbrook; Marie H Hanigan; Richard D Cummings
Journal:  Cancer Res       Date:  2008-03-15       Impact factor: 12.701

10.  Reduced expression of TANGO in colon and hepatocellular carcinomas.

Authors:  Stephanie Arndt; Anja K Bosserhoff
Journal:  Oncol Rep       Date:  2007-10       Impact factor: 3.906
  10 in total
  4 in total

1.  Celebrating science's next generation.

Authors:  Lila M Gierasch; George DeMartino
Journal:  J Biol Chem       Date:  2019-03-01       Impact factor: 5.157

Review 2.  Towards structure-focused glycoproteomics.

Authors:  Anastasia Chernykh; Rebeca Kawahara; Morten Thaysen-Andersen
Journal:  Biochem Soc Trans       Date:  2021-02-26       Impact factor: 5.407

3.  GALNT6 Knockdown Inhibits the Proliferation and Migration of Colorectal Cancer Cells and Increases the Sensitivity of Cancer Cells to 5-FU.

Authors:  Xiangdong Peng; Xueru Chen; Xiuting Zhu; Ling Chen
Journal:  J Cancer       Date:  2021-10-30       Impact factor: 4.207

4.  Altered O-glycomes of Renal Brush-Border Membrane in Model Rats with Chronic Kidney Diseases.

Authors:  Aiying Yu; Jingfu Zhao; Jieqiang Zhong; Junyao Wang; Shiv Pratap S Yadav; Bruce A Molitoris; Mark C Wagner; Yehia Mechref
Journal:  Biomolecules       Date:  2021-10-21
  4 in total

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