| Literature DB >> 29368391 |
Frank de Vocht1,2, Jamie Brown1,3,4, Emma Beard1,3,4, Robert West4, Susan Michie1,3, Rona Campbell1,2, Matthew Hickman1,2.
Abstract
AIMS: To assess how far motivation to reduce alcohol consumption in increasing and higher-risk drinkers in England predicts self-reported attempts to reduce alcohol consumption and changes in alcohol intake during the following 6 months.Entities:
Keywords: ATS; Alcohol; Alcohol Toolkit Study; audit; behaviour; consumption; motivation
Mesh:
Year: 2018 PMID: 29368391 PMCID: PMC5947299 DOI: 10.1111/add.14132
Source DB: PubMed Journal: Addiction ISSN: 0965-2140 Impact factor: 6.526
Sample demographics.
| Full ATS (weighted) | Followed‐up | Followed‐up and wanting to reduce alcohol | |||||||
|---|---|---|---|---|---|---|---|---|---|
| all data | (%) | High risk | (%) | Unweighted | (%) | Unweighted | (%) | ||
|
| 57341.0 | 14978.0 | 2928 | 686 | |||||
| Sex | Male | 28100.0 | 49.0 | 9903.0 | 66.1 | 1902 | 65.0 | 407 | 59.3 |
| Female | 29245.7 | 51.0 | 5588.9 | 37.3 | 1026 | 35.0 | 279 | 40.7 | |
| Age (years) | 16–24 | 8223.8 | 14.3 | 2856.8 | 19.1 | 347 | 11.9 | 54 | 7.9 |
| 25–34 | 9590.7 | 16.7 | 2615.5 | 17.5 | 277 | 9.5 | 55 | 8.0 | |
| 35–44 | 9567.7 | 16.7 | 2660.3 | 17.8 | 405 | 13.8 | 104 | 15.2 | |
| 45–54 | 9967.6 | 17.4 | 3195.4 | 21.3 | 599 | 20.5 | 170 | 24.8 | |
| 55–64 | 8055.6 | 14.0 | 2304.7 | 15.4 | 647 | 22.1 | 158 | 23.0 | |
| 65+ | 11940.4 | 20.8 | 1859.1 | 12.4 | 653 | 22.3 | 145 | 21.1 | |
| NRS social grade | AB | 15504.3 | 27.0 | 5003.4 | 33.4 | 1053 | 36.0 | 269 | 39.2 |
| C1 | 15730.1 | 27.4 | 4611.6 | 30.8 | 1005 | 34.3 | 246 | 35.9 | |
| C2 | 12604.8 | 22.0 | 3420.6 | 22.8 | 455 | 15.5 | 82 | 12.0 | |
| D | 8638.2 | 15.1 | 1575.9 | 10.5 | 240 | 8.2 | 51 | 7.4 | |
| E | 4868.4 | 8.5 | 880.4 | 5.9 | 175 | 6.0 | 38 | 5.5 | |
| Region | London | 4660.8 | 8.1 | 716.8 | 4.8 | 200 | 6.8 | 59 | 8.6 |
| South East | 8371.6 | 14.6 | 2244.5 | 15.0 | 366 | 12.5 | 115 | 16.8 | |
| South West | 3359.4 | 5.9 | 815.9 | 5.4 | 177 | 6.0 | 39 | 5.7 | |
| East Anglia | 1277.2 | 2.2 | 344.1 | 2.3 | 61 | 2.1 | 11 | 1.6 | |
| East Midlands | 2971.8 | 5.2 | 623.5 | 4.2 | 108 | 3.7 | 30 | 4.4 | |
| West Midlands | 3245.9 | 5.7 | 671 | 4.5 | 159 | 5.4 | 41 | 6.0 | |
| Yorks/Humberside | 3439.6 | 6.0 | 1257.5 | 8.4 | 355 | 12.1 | 63 | 9.2 | |
| North West | 3862.5 | 6.7 | 1371.2 | 9.2 | 302 | 10.3 | 69 | 10.1 | |
| North | 2323.4 | 4.1 | 894.3 | 6.0 | 200 | 6.8 | 48 | 7.0 | |
| Life stage | Single | 8168.9 | 14.2 | 3165.6 | 21.1 | 357 | 12.2 | 66 | 9.6 |
| Pre‐family | 3680.8 | 6.4 | 1293.5 | 8.6 | 163 | 5.6 | 28 | 4.1 | |
| Family | 17833.3 | 31.1 | 4300.7 | 28.7 | 696 | 23.8 | 172 | 25.1 | |
| Post‐family | 27582.7 | 48.1 | 6723.2 | 44.9 | 1712 | 58.5 | 420 | 61.2 | |
| Ethnicity | White | 49385.6 | 86.1 | 14910.3 | 99.5 | 2817 | 96.2 | 656 | 95.6 |
| Non‐white | 7684.3 | 13.4 | 519.7 | 3.5 | 100 | 3.4 | 28 | 4.1 | |
| Plan to cut down on alcohol use | No | 12462.7 | 21.7 | 12351.2 | 82.5 | 2242 | 76.6 | 0 | 0.0 |
| Yes | 3162.4 | 5.5 | 3133.6 | 20.9 | 686 | 23.4 | 686 | 100.0 | |
| AUDIT‐C‐positive (≥ 4) | No | 35 397,5 | 61.7 | 73.0 | 0.5 | 13 | 0.4 | 5 | 0.7 |
| Yes | 21948.3 | 38.3 | 15419.0 | 99.5 | 2915 | 99.6 | 681 | 99.3 | |
| Qualification | GCSE/O‐level/CSE | 11181.5 | 19.5 | 2822.8 | 18.8 | 497 | 17.0 | 113 | 16.5 |
| Vocational | 5063.4 | 8.8 | 1533.4 | 10.2 | 248 | 8.5 | 56 | 8.2 | |
| A‐level or equivalent | 10695.7 | 18.7 | 3605.3 | 24.1 | 600 | 20.5 | 125 | 18.2 | |
| Bachelor degree (or equivalent) | 13054.1 | 22.8 | 3944.7 | 26.3 | 854 | 29.2 | 213 | 31.0 | |
| Masters or PhD (or equivalent) | 4477.1 | 7.8 | 1371.8 | 9.2 | 305 | 10.4 | 106 | 15.5 | |
| Other | 3807 | 6.6 | 921 | 6.1 | 175 | 6.0 | 38 | 5.5 | |
| No formal qualification | 8335.5 | 14.5 | 1143.9 | 7.6 | 227 | 7.8 | 32 | 4.7 | |
| Studying | 479.6 | 0.8 | 116.6 | 0.8 | 16 | 0.5 | 2 | 0.3 | |
| Don't know | 251.9 | 0.4 | 32.5 | 0.2 | 6 | 0.2 | 1 | 0.1 | |
Two people deleted because of missing Alcohol Use Disorders Identification Test (AUDIT) answers;
AUDIT‐C score > 4 or AUDIT score > 7;
higher and intermediate managerial, administrative, professional occupations (AB); supervisory, clerical and junior managerial, administrative, professional occupations (C1); skilled manual occupations (C2); semi‐skilled and unskilled manual occupations, unemployed and lowest‐grade occupations (D); semi‐skilled and unskilled manual occupations, unemployed and lowest‐grade occupations (E).
single is defined as up to aged 39, not married and no children in household; pre‐family is aged up to 39, married or living with partner, no children in household; family (children in household); post‐family is aged 40 and above and no children in household. ATS = Alcohol Toolkit Study.
Figure 1Histogram of Alcohol Use Disorders Identification Test (AUDIT)‐C scores at the initial survey and follow‐up, stratified by motivation to reduce intake now (definition 1) reported in the initial survey. [Colour figure can be viewed at http://wileyonlinelibrary.com]
Repeated measures ordinal regression model results for Alcohol Use Disorders Identification Test‐C (AUDIT‐C) score (n = 2928).
| Variable | Crude estimates | Adjusted estimates | No DID (adjusted estimates | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Estimate (log‐odds) | 95% profile likelihood |
| Estimate (log‐odds) | 95% profile likelihood |
| Estimate (log‐odds) | 95% profile likelihood |
| |
| AUDIT‐C sum score | |||||||||
| Wanting to reduce intake | 0.555 | 0.265: 0.846 | < 0.001 | 0.413 | 0.117: 0.710 | 0.006 | 0.564 | 0.310: 0.819 | < 0.001 |
| AUDIT‐C at follow‐up (6 months) | −0.351 | −0.451: −0.252 | < 0.001 | −0.334 | −0.437: −0.231 | < 0.001 | −0.303 | −0.401: −0.205 | < 0.001 |
| DID interaction | 0.326 | 0.009: 0.644 | 0.044 | 0.314 | −0.003: 0.630 | 0.052 | NA | ||
| Relative DID effect | +3.8% | +3.9% | |||||||
| Bayes factor (BF10) | > 100 | 2.72 | 31.59 | ||||||
| How often do you have a drink containing alcohol? (AUDIT question 1) | |||||||||
| Wanting to reduce intake | 0.717 | 0.196: 1.238 | 0.007 | 0.592 | 0.119: 1.065 | 0.014 | 0.744 | 0.306: 1.181 | < 0.001 |
| Frequency at follow‐up (6 months) | −0.675 | −0.790: −0.560 | < 0.001 | −0.633 | −0.753: −0.512 | < 0.001 | −0.601 | −0.715: −0.487 | < 0.001 |
| DID interaction | 0.410 | 0.064: 0.756 | 0.020 | 0.301 | −0.058: 0.660 | 0.101 | NA | ||
| Relative DID effect | +2.5% | +2.4% | |||||||
| BF10 | 0.00 | > 100 | > 100 | ||||||
| How many units of alcohol do you drink on a typical day when you are drinking? (AUDIT question 2) | |||||||||
| Wanting to reduce intake | 0.063 | −0.240: 0.365 | 0.686 | 0.062 | −0.235: 0.359 | 0.683 | 0.130 | −0.122: 0.381 | 0.312 |
| Quantity at follow‐up (6 months) | −0.371 | −0.473: −0.269 | < 0.001 | −0.360 | −0.465: −0.255 | < 0.001 | −0.346 | −0.446: −0.247 | < 0.001 |
| DID interaction | 0.141 | −0.182: 0.464 | 0.393 | 0.138 | −0.184: 0.459 | 0.401 | NA | ||
| Relative DID effect | +1.6% | +1.6% | |||||||
| BF10 | > 100 | > 100 | > 100 | ||||||
| How often have you had 6 or more units if female, or 8 or more if male, on a single occasion in the last year? (AUDIT question 3) | |||||||||
| Wanting to reduce | 0.623 | 0.332: 0.913 | < 0.001 | 0.452 | 0.154: 0.749 | 0.003 | 0.534 | 0.284: 0.784 | < 0.001 |
| Binge frequency at follow‐up (6 months) | 0.040 | −0.062: 0.143 | 0.442 | 0.064 | −0.041: 0.170 | 0.234 | 0.081 | −0.020: 0.181 | 0.117 |
| DID interaction | 0.182 | −0.146: 0.509 | 0.277 | 0.166 | −0.160: 0.493 | 0.318 | NA | ||
| Relative DID effect | +2.7% | +2.6% | |||||||
| BF10 | > 100 | 0.00 | 0.00 | ||||||
22 observations removed because of missing covariate data. Adjusted for: wave, season of interview or follow‐up, sex, age, social grade, life stage, ethnicity, qualification and ‘at least one serious attempt to cut down drinking in previous 6 months’;
difference‐in‐differences (DID) effect;
least squares means contrast in AUDIT score at follow‐up averaged over other covariates;
compared to intercept‐only model;
compared to ‘crude estimate’ model;
log‐odds are presented to enable calculation of linear combinations of estimates (for example, OR for DID effect of participants motivated to reduce intake in model 1 = e(0.555–0.351 + 0.326). OR = odds ratio; NA = not available.
Figure 2Example: average change in Alcohol Use Disorders Identification Test (AUDIT)‐C score relative to non‐motivated baseline score. Note that follow‐up odds ratios are calculated as exp(βmotivation + βtime (+ βDIDinteraction)). [Colour figure can be viewed at http://wileyonlinelibrary.com]
Repeated measures ordinal regression model results for Alcohol Use Disorders Identification Test‐C (AUDIT‐C) score, stratified by severity.
| Variable | Increasing risk ( | Higher risk and possible dependency ( | ||||
|---|---|---|---|---|---|---|
| Estimate | 95% profile likelihood |
| Estimate | 95% profile likelihood |
| |
| AUDIT‐C sum score | ||||||
| Wanting to reduce intake | −0.358 | −0.720: 0.004 | 0.052 | 0.156 | −0.677: 0.988 | 0.714 |
| AUDIT‐C at follow‐up (6 months) | −0.689 | −0.838: −0.539 | < 0.01 | −1.067 | −1.550: −0.584 | < 0.001 |
| DID interaction | 0.592 | 0.157: 1.026 | 0.008 | −0.947 | −1.847: −0.047 | 0.040 |
| Relative DID effect | +6.8% | −9.5% | ||||
| Bayes factor (BF10) | > 100 | > 100 | ||||
| How often do you have a drink containing alcohol? (AUDIT question 1) | ||||||
| Wanting to reduce intake | 0.483 | −0.239: 1.205 | 0.190 | 0.654 | −0.447: 1.754 | 0.244 |
| Frequency at follow‐up (6 months) | −0.788 | −0.966: −0.610 | < 0.001 | −0.780 | −1.325: −0.266 | 0.003 |
| DID interaction | 0.489 | −0.002: 0.981 | 0.051 | −0.502 | −1.512: 0.507 | 0.330 |
| Relative DID effect | +3.0% | −5.1% | ||||
| BF10 | > 100 | 1.19 | ||||
| How many units of alcohol do you drink on a typical day when you are drinking? (AUDIT question 2) | ||||||
| Wanting to reduce intake | −0.696 | −1.085: −0.306 | < 0.001 | −0.443 | −1.194: 0.308 | 0.248 |
| Quantity at follow‐up (6 months) | −0.596 | −0.748: −0.444 | < 0.001 | −0.905 | −1.386: −0.424 | < 0.001 |
| DID interaction | 0.303 | −0.133: 0.739 | 0.173 | −0.529 | −1.401: 0.344 | 0.235 |
| Relative DID effect | +4.9% | −8.3% | ||||
| BF10 | > 100 | > 100 | ||||
| How often have you had 6 or more units if female, or 8 or more if male, on a single occasion in the last year? (AUDIT question 3) | ||||||
| Wanting to reduce | −0.283 | −0.652: 0.086 | 0.133 | 0.317 | −0.630: 1.264 | 0.512 |
| Binge frequency at follow‐up (6 months) | −0.432 | −0.588: −0.276 | < 0.001 | −0.889 | −1.430: −0.348 | 0.001 |
| DID interaction | 0.542 | 0.090: 0.994 | 0.019 | −0.806 | −1.807: 0.196 | 0.115 |
| Relative DID effect | +6.4% | −5.1% | ||||
| BF10 | 24.4 | 36.6 | ||||
Models not adjusted further for covariates, because BF10 were all ~ 0, indicating no statistical power to differentiate between null model and more complex multivariable models;
difference‐in‐differences (DID) effect;
least‐squares means contrast in AUDIT score at follow‐up averaged over other covariates;
least‐squares means difference.
Logistic regression model results for attempt to reduce alcohol consumption.
| Variable | Crude estimates | Adjusted estimates | ||||
|---|---|---|---|---|---|---|
| Odds ratio | 95% profile likelihood |
| Odds ratio | 95% profile likelihood |
| |
| At least one attempt to cut down drinking in previous 6 months ( | ||||||
| Wanting to reduce intake in next 3 months (initial survey) | 5.82 | 4.49: 7.58 | < 0.001 | 2.39 | 1.75: 3.29 | < 0.001 |
| AUDIT‐C | 1.14 | 1.08: 1.19 | < 0.001 | |||
| Trying to reduce consumption at initial survey | 0.62 | 0.41: 0.93 | 0.020 | |||
| having tried to reduce in previous 12 months (initial survey) | 2.56 | 1.73: 3.78 | < 0.001 | |||
| Bayes factor (BF10) | > 100 | > 100 | ||||
| At least one attempt to cut down drinking in previous 6 months—people who had not made an attempt in year prior to 1st interview only ( | ||||||
| Wanting to reduce intake in next 3 months (initial survey) | 2.09 | 1.16: 3.68 | 0.012 | 1.37 | 0.71: 2.57 | 0.341 |
| AUDIT‐C | 1.14 | 1.07: 1.21 | < 0.001 | |||
| Having tried to reduce in previous 12 months (initial survey) | 2.74 | 1.83: 4.07 | < 0.001 | |||
| BF10 | > 100 | > 100 | ||||
| At least one serious attempt to cut down drinking in previous 6 months ( | ||||||
| Wanting to reduce intake in next 3 months (initial survey) | 4.41 | 3.37: 5.76 | < 0.001 | 1.96 | 1.41: 2.72 | < 0.001 |
| AUDIT‐C | 1.08 | 1.01: 1.14 | 0.020 | |||
| Trying to reduce consumption at initial survey | 0.42 | 0.32: 0.55 | < 0.001 | |||
| having tried to reduce in previous 12 months (initial survey) | 1.92 | 1.38: 2.66 | < 0.001 | |||
| BF10 | > 100 | 0.00 | ||||
| At least one serious attempt to cut down drinking in previous 6 months—people who had not made an attempt in year prior to 1st interview only ( | ||||||
| Wanting to reduce intake in next 3 months (initial survey) | 2.68 | 1.29: 5.12 | 0.005 | 1.89 | 0.83: 3.96 | 0.107 |
| AUDIT‐C | 1.12 | 1.03: 1.21 | 0.010 | |||
| Having tried to reduce in previous 12 months (initial survey) | 1.88 | 1.08: 3.96 | 0.020 | |||
| BF10 | 0.601 | 0.00 | ||||
n = 2662. Adjusted for wave, season of follow‐up interview, sex, age, social grade, life stage, ethnicity, qualification, initial Alcohol Use Disorders Identification Test‐C score, having tried to reduce alcohol consumption in the 12 months prior to the initial survey and trying to reduce consumption at initial survey;
compared to intercept‐only model;
compared to ‘crude estimate’ model.