Literature DB >> 29368279

The clinical utility of pre-operative neutrophil-to-lymphocyte ratio as a predictor of outcomes in patients undergoing elective laparoscopic cholecystectomy.

Brian M Moloney1, Ronan M Waldron2, Niamh O' Halloran2, Michael E Kelly3, Eddie Myers3, Joseph T Garvin3, Michael J Kerin2, Chris G Collins3.   

Abstract

BACKGROUND: In recent years, there has been an increasing trend towards day-case surgery for patients undergoing laparoscopic cholecystectomy (LC). We investigated the predictive value that pre-operative neutrophil-to-lymphocyte ratio (PNLR) had on surgical outcomes.
METHODS: A review of all patients who underwent LC during a 6-year period in a single institution was performed and PNLR recorded. A PNLR cutoff value of 3 was utilised. We compared operation time, length of stay (LOS), and conversion to open between those with PNLR less and greater than 3.
RESULTS: A total of 567 patients underwent elective LC. Those with PNLR>3 had associated prolonged operation time (p < 0.005), prolonged LOS (p < 0.005), and higher rates of conversion to open surgery (p < 0.005).
CONCLUSIONS: PNLR correlates with outcomes following LC. It is useful in delineating patients that have higher risk of conversion or prolonged length of hospital stay and is helpful in assessing suitability of day-case surgery.

Entities:  

Keywords:  Laparoscopic cholecystectomy; Minimally invasive surgery; Neutrophil-to-lymphocyte ratio; Surgical outcomes

Mesh:

Year:  2018        PMID: 29368279     DOI: 10.1007/s11845-018-1749-6

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  29 in total

1.  A prospective study of common bile duct calculi in patients undergoing laparoscopic cholecystectomy: natural history of choledocholithiasis revisited.

Authors:  Chris Collins; Donal Maguire; Adrian Ireland; Edward Fitzgerald; Gerald C O'Sullivan
Journal:  Ann Surg       Date:  2004-01       Impact factor: 12.969

2.  Cost utility of early versus delayed laparoscopic cholecystectomy for acute cholecystitis.

Authors:  Amanda Johner; Adam Raymakers; Sam M Wiseman
Journal:  Surg Endosc       Date:  2012-07-07       Impact factor: 4.584

3.  Reduced postoperative hospitalization after laparoscopic cholecystectomy.

Authors:  P A Grace; A Quereshi; J Coleman; R Keane; G McEntee; P Broe; H Osborne; D Bouchier-Hayes
Journal:  Br J Surg       Date:  1991-02       Impact factor: 6.939

4.  A prospective randomized trial of day-stay only versus overnight-stay laparoscopic cholecystectomy.

Authors:  P Hollington; G J Toogood; R T Padbury
Journal:  Aust N Z J Surg       Date:  1999-12

5.  Inhibition of human cytotoxic T lymphocyte activity in vitro by autologous peripheral blood granulocytes.

Authors:  H T Petrie; L W Klassen; H D Kay
Journal:  J Immunol       Date:  1985-01       Impact factor: 5.422

6.  Does neutrophil-to-lymphocyte ratio predict active ulcerative colitis?

Authors:  Emrah Posul; Bulent Yilmaz; Gulali Aktas; Mevlut Kurt
Journal:  Wien Klin Wochenschr       Date:  2015-01-10       Impact factor: 1.704

7.  High mortality associated with hyperglycemia, neutrophilia, and lymphopenia in critically ill patients.

Authors:  Enrique O Jiménez-Ibáñez; Manuel Castillejos-López; Andrés Hernández; Patricia Gorocica; Noé Alvarado-Vásquez
Journal:  Tohoku J Exp Med       Date:  2012-03       Impact factor: 1.848

8.  Pre-treatment neutrophil to lymphocyte ratio is elevated in epithelial ovarian cancer and predicts survival after treatment.

Authors:  Hanbyoul Cho; Hye Won Hur; Sang Wun Kim; Sung Hoon Kim; Jae Hoon Kim; Young Tae Kim; Kook Lee
Journal:  Cancer Immunol Immunother       Date:  2008-04-15       Impact factor: 6.968

9.  Laparoscopic cholecystectomy. Treatment of choice for symptomatic cholelithiasis.

Authors:  B D Schirmer; S B Edge; J Dix; M J Hyser; J B Hanks; R S Jones
Journal:  Ann Surg       Date:  1991-06       Impact factor: 12.969

10.  Introduction of a day-case laparoscopic cholecystectomy service in the UK: a critical analysis of factors influencing same-day discharge and contact with primary care providers.

Authors:  C D Briggs; G B Irving; C D Mann; A Cresswell; L Englert; M Peterson; I C Cameron
Journal:  Ann R Coll Surg Engl       Date:  2009-06-25       Impact factor: 1.891

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