Literature DB >> 29367110

Antidotal or protective effects of Curcuma longa (turmeric) and its active ingredient, curcumin, against natural and chemical toxicities: A review.

Azar Hosseini1, Hossein Hosseinzadeh2.   

Abstract

Curcuma longa is a rhizomatous perennial herb that belongs to the family Zingiberaceae, native to South Asia and is commonly known as turmeric. It is used as herbal remedy due to the prevalent belief that the plant has medical properties. C. longa possesses different effects such as antioxidant, anti-tumor, antimicrobial, anti-inflammatory, wound healing, and gastroprotective activities. The recent studies have shown that C. longa and curcumin, its important active ingredient, have protective effects against toxic agents. In this review article, we collected in vitro and animal studies which are related to protective effects of turmeric and its active ingredient against natural and chemical toxic agents.
Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Chemical toxins; Curcuma longa; Curcumin; Natural toxins; Protective effects; Toxicology

Mesh:

Substances:

Year:  2018        PMID: 29367110     DOI: 10.1016/j.biopha.2018.01.072

Source DB:  PubMed          Journal:  Biomed Pharmacother        ISSN: 0753-3322            Impact factor:   6.529


  19 in total

Review 1.  Metformin as a protective agent against natural or chemical toxicities: a comprehensive review on drug repositioning.

Authors:  S E Meshkani; D Mahdian; K Abbaszadeh-Goudarzi; M Abroudi; G Dadashizadeh; J-D Lalau; M E De Broe; H Hosseinzadeh
Journal:  J Endocrinol Invest       Date:  2019-05-16       Impact factor: 4.256

2.  Radiosensitizing effect of dendrosomal nanoformulation of curcumin on cancer cells.

Authors:  Tahereh Jalali Varnamkhasti; Meisam Jafarzadeh; Majid Sadeghizadeh; Mahdi Aghili
Journal:  Pharmacol Rep       Date:  2022-07-10       Impact factor: 3.919

Review 3.  Protective and therapeutic effects of Scutellaria baicalensis and its main active ingredients baicalin and baicalein against natural toxicities and physical hazards: a review of mechanisms.

Authors:  Ali Ahmadi; Zoha Mortazavi; Soghra Mehri; Hossein Hosseinzadeh
Journal:  Daru       Date:  2022-07-23       Impact factor: 4.088

4.  Eco-Friendly Synthesis of PEtOz-PA: A Promising Polymer for the Formulation of Curcumin-Loaded Micelles.

Authors:  Monica Nardi; Emiliana Sarubbi; Satyanarayana Somavarapu
Journal:  Molecules       Date:  2022-06-12       Impact factor: 4.927

5.  Curcumin protects islet cells from glucolipotoxicity by inhibiting oxidative stress and NADPH oxidase activity both in vitro and in vivo.

Authors:  Jing Li; Ninghua Wu; Xiao Chen; Hongguang Chen; Xiaosong Yang; Chao Liu
Journal:  Islets       Date:  2019-11-21       Impact factor: 2.694

6.  Ameliorative effect of curcumin against lead acetate-induced hemato-biochemical alterations, hepatotoxicity, and testicular oxidative damage in rats.

Authors:  Fatma M Abdelhamid; Hebatallah A Mahgoub; Ahmed I Ateya
Journal:  Environ Sci Pollut Res Int       Date:  2020-01-17       Impact factor: 4.223

7.  Curcumin‑loaded PEG‑PDLLA nanoparticles for attenuating palmitate‑induced oxidative stress and cardiomyocyte apoptosis through AMPK pathway.

Authors:  Jingyi Zhang; Ying Wang; Cuiyu Bao; Tao Liu; Shuai Li; Jiaxi Huang; Ying Wan; Jing Li
Journal:  Int J Mol Med       Date:  2019-06-05       Impact factor: 4.101

Review 8.  The Autophagy Signaling Pathway: A Potential Multifunctional Therapeutic Target of Curcumin in Neurological and Neuromuscular Diseases.

Authors:  Lorena Perrone; Tiziana Squillaro; Filomena Napolitano; Chiara Terracciano; Simone Sampaolo; Mariarosa Anna Beatrice Melone
Journal:  Nutrients       Date:  2019-08-13       Impact factor: 5.717

9.  Bioactivity of Curcumin on the Cytochrome P450 Enzymes of the Steroidogenic Pathway.

Authors:  Patricia Rodríguez Castaño; Shaheena Parween; Amit V Pandey
Journal:  Int J Mol Sci       Date:  2019-09-17       Impact factor: 5.923

Review 10.  Biochemistry, Safety, Pharmacological Activities, and Clinical Applications of Turmeric: A Mechanistic Review.

Authors:  Rabia Shabir Ahmad; Muhammad Bilal Hussain; Muhammad Tauseef Sultan; Muhammad Sajid Arshad; Marwa Waheed; Mohammad Ali Shariati; Sergey Plygun; Mohammad Hashem Hashempur
Journal:  Evid Based Complement Alternat Med       Date:  2020-05-10       Impact factor: 2.629

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