Literature DB >> 2936678

MRC OX-43: a monoclonal antibody which reacts with all vascular endothelium in the rat except that of brain capillaries.

A P Robinson, T M White, D W Mason.   

Abstract

A mouse monoclonal antibody, MRC OX-43, has been shown to label vascular endothelium in all tissues of the rat except that of brain capillaries. Using immunoperoxidase staining, the antigen was shown to be expressed on the luminal surface of blood vessels. In addition, this antibody recognized a surface antigen on circulating erythrocytes and some macrophage populations, namely all those in the peritoneal cavity and a subset of alveolar macrophages. The antigen recognized by this antibody was identified on macrophages by metabolic and cell surface labelling followed by immunoprecipitation and sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) and found to be a surface protein of 90,000 MW.

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Year:  1986        PMID: 2936678      PMCID: PMC1453944     

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  36 in total

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Authors:  R A Laskey; A D Mills
Journal:  Eur J Biochem       Date:  1975-08-15

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Authors:  J L GOWANS; E J KNIGHT
Journal:  Proc R Soc Lond B Biol Sci       Date:  1964-01-14

Review 3.  Is the lung a para-endocrine organ?

Authors:  H O Heinemann; J W Ryan; U S Ryan
Journal:  Am J Med       Date:  1977-10       Impact factor: 4.965

4.  The immune response to allogeneic rat platelets; Ag-B antigens in matrix form lacking Ia.

Authors:  K I Welsh; H Burgos; J R Batchelor
Journal:  Eur J Immunol       Date:  1977-05       Impact factor: 5.532

5.  Prolonged lymphocytopenia in the rat. the immunological consequences of lymphocyte depletion following injection of 185 W tungsten trioxide into the spleen of lymph nodes.

Authors:  B Roser; W L Ford
Journal:  Aust J Exp Biol Med Sci       Date:  1972-04

6.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

7.  Differences in the surface proteins of mouse B and T cells.

Authors:  I S Trowbridge; P Ralph; M J Bevan
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

8.  Purification of human C3b inactivator by monoclonal-antibody affinity chromatography.

Authors:  L Hsiung; A N Barclay; M R Brandon; E Sim; R R Porter
Journal:  Biochem J       Date:  1982-04-01       Impact factor: 3.857

9.  Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion.

Authors:  G Köhler; C Milstein
Journal:  Eur J Immunol       Date:  1976-07       Impact factor: 5.532

10.  Identification and characterization of the monoblast in mononuclear phagocyte colonies grown in vitro.

Authors:  T J Goud; C Schotte; R van Furth
Journal:  J Exp Med       Date:  1975-11-01       Impact factor: 14.307

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  20 in total

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Journal:  Cell Tissue Res       Date:  1992-07       Impact factor: 5.249

2.  Cell culture from rat renal glomeruli.

Authors:  S Ringstead; G B Robinson
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064

3.  Innervation and neurokinin receptors during angiogenesis in the rat sponge granuloma.

Authors:  D A Walsh; D E Hu; P I Mapp; J M Polak; D R Blake; T P Fan
Journal:  Histochem J       Date:  1996-11

4.  T-cell lymphoma lines derived from rat thymomas induced by Moloney murine leukemia virus: phenotypic diversity and its implications.

Authors:  P A Lazo; A J Klein-Szanto; P N Tsichlis
Journal:  J Virol       Date:  1990-08       Impact factor: 5.103

5.  Localization of T cells, macrophages and dendritic cells in rat respiratory tract tissue: implications for immune function studies.

Authors:  P G Holt; M A Schon-Hegrad
Journal:  Immunology       Date:  1987-11       Impact factor: 7.397

6.  Lymphocyte expression of a 90 kD brush border antigen.

Authors:  E H Van Leer; P Moullier; P Ronco; P Verroust
Journal:  Clin Exp Immunol       Date:  1987-03       Impact factor: 4.330

7.  FcR+/- subsets of Ia+ pulmonary dendritic cells in the rat display differences in their abilities to provide accessory co-stimulation for naive (OX-22+) and sensitized (OX-22-) T cells.

Authors:  R L Kradin; W Xia; K McCarthy; E E Schneeberger
Journal:  Am J Pathol       Date:  1993-03       Impact factor: 4.307

8.  Reversible endothelial cell relaxation induced by oxygen and glucose deprivation. A model of ischemia in vitro.

Authors:  J Doukas; A H Cutler; C A Boswell; I Joris; G Maino
Journal:  Am J Pathol       Date:  1994-07       Impact factor: 4.307

Review 9.  Organ-preference of metastasis. The role of endothelial cell adhesion molecules.

Authors:  B U Pauli; H G Augustin-Voss; M E el-Sabban; R C Johnson; D A Hammer
Journal:  Cancer Metastasis Rev       Date:  1990-11       Impact factor: 9.264

10.  Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3.

Authors:  A P Robinson; T M White; D W Mason
Journal:  Immunology       Date:  1986-02       Impact factor: 7.397

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