Literature DB >> 2936619

7-trans-(2-Pyridylethenyl)-5H-thiazolo[3,2-a]pyrimidine-5-ones: synthesis and pharmacological activity.

G Doria, C Passarotti, R Sala, R Magrini, P Sberze, M Tibolla, R Ceserani, G Arcari, R Castello, D Toti.   

Abstract

A series of 7-trans-(2-pyridylethenyl)-5H-thiazolo[3,2-a]pyrimidine-5-ones was synthesized and evaluated for their pharmacological activity. Some compounds were found to be effective in inhibiting restraint ulcers in the rat. Two of them also showed interesting antiinflammatory activity.

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Year:  1985        PMID: 2936619

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN: 0430-0920


  2 in total

1.  A rapid access to novel and diverse 3-oxothiazolo[3,2-c]pyrimidine-8-carboxylates using multicomponent Mannich cyclisation reactions.

Authors:  Muhammet Yıldırım; Derya Çelikel
Journal:  Mol Divers       Date:  2014-08-24       Impact factor: 2.943

2.  Synthesis, Antibacterial and Antitubercular Activities of Some 5H-Thiazolo[3,2-a]pyrimidin-5-ones and Sulfonic Acid Derivatives.

Authors:  Dong Cai; Zhi-Hua Zhang; Yu Chen; Xin-Jia Yan; Liang-Jing Zou; Ya-Xin Wang; Xue-Qi Liu
Journal:  Molecules       Date:  2015-09-10       Impact factor: 4.411

  2 in total

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