| Literature DB >> 29363460 |
Mya Myat Ngwe Tun1, Aung Kyaw Kyaw2,1, Saw Wut Hmone3, Shingo Inoue1, Corazon C Buerano4,1, Aung Min Soe2,1, Meng Ling Moi1, Daisuke Hayasaka1, Hlaing Myat Thu2, Futoshi Hasebe1, Kyaw Zin Thant2, Kouichi Morita1.
Abstract
Zika virus (ZIKV), an emerging mosquito-borne flavivirus, causes a dengue-like infection that has recently caught global attention. The infection, which also includes some birth defects, has been documented in the Americas, Pacific Islands, and some parts of Africa and Asia. There are no published reports on local ZIKV transmission in Myanmar. In this study, a total of 462 serum samples from patients and asymptomatic persons were collected in Myanmar from 2004 to 2017. They were analyzed for ZIKV infection by immunoglobulin M capture enzyme-linked immunosorbent assay (ELISA), immunoglobulin G indirect ELISA, neutralization test, real-time polymerase chain reaction (PCR), and conventional PCR. Our study confirmed ZIKV infection in 4.9% of patients with clinical dengue symptoms and in 8.6% of persons who were asymptomatic. This is the first report on ZIKV infection in Myanmar and it suggests the occurrence of ZIKV infection in two geographically distinct sites in this country since at least 2006.Entities:
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Year: 2018 PMID： 29363460 PMCID： PMC5930904 DOI： 10.4269/ajtmh.17-0708
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN： 0002-9637 Impact factor: 2.345