Literature DB >> 29358180

Loss of Toll-like receptor 2 results in accelerated leukemogenesis in the NUP98-HOXD13 mouse model of MDS.

Darlene A Monlish1, Sima T Bhatt1, Eric J Duncavage2, Zev J Greenberg1, John L Keller1, Molly P Romine1, Wei Yang3, Peter D Aplan4, Matthew J Walter5, Laura G Schuettpelz1.   

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Year:  2018        PMID： 29358180      PMCID： PMC5833264          DOI： 10.1182/blood-2017-08-801944

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


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  18 in total

1.  The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS.

Authors:  J E Parker; G J Mufti; F Rasool; A Mijovic; S Devereux; A Pagliuca
Journal:  Blood       Date:  2000-12-01       Impact factor: 22.113

Review 2.  Myelodysplastic syndromes: 2015 Update on diagnosis, risk-stratification and management.

Authors:  Guillermo Garcia-Manero
Journal:  Am J Hematol       Date:  2015-09       Impact factor: 10.047

Review 3.  Deconstructing innate immune signaling in myelodysplastic syndromes.

Authors:  Madeline Niederkorn; Molly Smith; Laura Barreyro; Melinda E Varney; Katelyn Melgar; Daniel T Starczynowski
Journal:  Exp Hematol       Date:  2015-07-02       Impact factor: 3.084

4.  Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromes.

Authors:  Christos I Maratheftis; Evangelos Andreakos; Haralampos M Moutsopoulos; Michael Voulgarelis
Journal:  Clin Cancer Res       Date:  2007-02-15       Impact factor: 12.531

5.  PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia.

Authors:  A A Guirguis; C I Slape; L M Failla; J Saw; C S Tremblay; D R Powell; F Rossello; A Wei; A Strasser; D J Curtis
Journal:  Cell Death Differ       Date:  2016-01-08       Impact factor: 15.828

6.  Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.

Authors:  Daniel T Starczynowski; Florian Kuchenbauer; Bob Argiropoulos; Sandy Sung; Ryan Morin; Andrew Muranyi; Martin Hirst; Donna Hogge; Marco Marra; Richard A Wells; Rena Buckstein; Wan Lam; R Keith Humphries; Aly Karsan
Journal:  Nat Med       Date:  2009-11-08       Impact factor: 53.440

7.  Impaired differentiation and apoptosis of hematopoietic precursors in a mouse model of myelodysplastic syndrome.

Authors:  Chul Won Choi; Yang Jo Chung; Christopher Slape; Peter D Aplan
Journal:  Haematologica       Date:  2008-07-04       Impact factor: 9.941

8.  Toll-like receptor alterations in myelodysplastic syndrome.

Authors:  Y Wei; S Dimicoli; C Bueso-Ramos; R Chen; H Yang; D Neuberg; S Pierce; Y Jia; H Zheng; H Wang; X Wang; M Nguyen; S A Wang; B Ebert; R Bejar; R Levine; O Abdel-Wahab; M Kleppe; I Ganan-Gomez; H Kantarjian; G Garcia-Manero
Journal:  Leukemia       Date:  2013-06-14       Impact factor: 11.528

9.  Apoptosis in human myelodysplastic syndrome CD34+ cells is modulated by the upregulation of TLRs and histone H4 acetylation via a β-arrestin 1 dependent mechanism.

Authors:  Qing Zeng; Jing Shu; Qi Hu; Shao-Hong Zhou; Yi-Ming Qian; Ming-Hui Hu; Ling-Yan Hu; Yu-Guang Wang; Yong-Ming Zhou; Jia-Hui Lu
Journal:  Exp Cell Res       Date:  2015-12-17       Impact factor: 3.905

10.  Overexpression of the toll-like receptor (TLR) signaling adaptor MYD88, but lack of genetic mutation, in myelodysplastic syndromes.

Authors:  Sophie Dimicoli; Yue Wei; Carlos Bueso-Ramos; Hui Yang; Courtney Dinardo; Yu Jia; Hong Zheng; Zhihong Fang; Martin Nguyen; Sherry Pierce; Rui Chen; Hui Wang; Chenghua Wu; Guillermo Garcia-Manero
Journal:  PLoS One       Date:  2013-08-15       Impact factor: 3.240
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  6 in total

Review 1.  Context-dependent functions of pattern recognition receptors in cancer.

Authors:  Si Ming Man; Brendan J Jenkins
Journal:  Nat Rev Cancer       Date:  2022-03-30       Impact factor: 69.800

Review 2.  Chronic immune response dysregulation in MDS pathogenesis.

Authors:  Laura Barreyro; Timothy M Chlon; Daniel T Starczynowski
Journal:  Blood       Date:  2018-08-13       Impact factor: 22.113

Review 3.  Contribution of Aberrant Toll Like Receptor Signaling to the Pathogenesis of Myelodysplastic Syndromes.

Authors:  Luana Chiquetto Paracatu; Laura G Schuettpelz
Journal:  Front Immunol       Date:  2020-06-17       Impact factor: 7.561

Review 4.  Diagnosis of Myelodysplastic Syndromes: From Immunological Observations to Clinical Applications.

Authors:  Yannick Simoni; Nicolas Chapuis
Journal:  Diagnostics (Basel)       Date:  2022-07-07

Review 5.  Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS.

Authors:  Jennifer J Trowbridge; Daniel T Starczynowski
Journal:  J Exp Med       Date:  2021-06-15       Impact factor: 17.579

6.  TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS.

Authors:  Darlene A Monlish; Zev J Greenberg; Sima T Bhatt; Kathryn M Leonard; Molly P Romine; Qian Dong; Lauren Bendesky; Eric J Duncavage; Jeffrey A Magee; Laura G Schuettpelz
Journal:  Exp Hematol       Date:  2020-07-08       Impact factor: 3.084
  6 in total

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