Literature DB >> 29349488

One-step synthesis of an 18F-labeled boron-derived methionine analog: a substitute for 11C-methionine?

Zhen Liu1,2, Emily B Ehlerding3, Weibo Cai4,5,6, Xiaoli Lan7,8.   

Abstract

Amino acid-based tracers have been extensively investigated for positron emission tomography (PET) imaging of brain tumors, and 11C-methionine (11C-MET) is one of the most extensively investigated. However, widespread clinical use of 11C-MET is challenging due to the short half-life of 11C and low radiolabeling yield. In this issue of the European Journal of Nuclear Medicine and Molecular Imaging, Yang and colleagues report an 18F-labeled boron-derived methionine analog, 18F-B-MET, as a potential substitute for 11C-MET in PET imaging of glioma. The push-button synthesis, highly efficient radiolabeling, and good imaging performance in glioma models make this tracer a promising candidate for future clinical translation.

Entities:  

Keywords:  11C-Methionine (11C-MET); 18F-B-MET; Amino acid transporter; Boramino acid; Cancer; Positron emission tomography (PET)

Mesh：

Substances：

Year:  2018        PMID： 29349488      PMCID： PMC5831531          DOI： 10.1007/s00259-017-3927-6

Source DB:  PubMed          Journal:  Eur J Nucl Med Mol Imaging        ISSN： 1619-7070            Impact factor:   9.236


  19 in total

Review 1.  A meta-analysis on the diagnostic performance of (18)F-FDG and (11)C-methionine PET for differentiating brain tumors.

Authors:  C Zhao; Y Zhang; J Wang
Journal:  AJNR Am J Neuroradiol       Date:  2013-09-12       Impact factor: 3.825

Review 2.  Radiolabeled amino acids for oncologic imaging.

Authors:  Chaofeng Huang; Jonathan McConathy
Journal:  J Nucl Med       Date:  2013-05-24       Impact factor: 10.057

3.  An organotrifluoroborate for broadly applicable one-step 18F-labeling.

Authors:  Zhibo Liu; Maral Pourghiasian; Mark Alex Radtke; Joseph Lau; Jinhe Pan; Gemma M Dias; Donald Yapp; Kuo-Shyan Lin; Francois Bénard; David M Perrin
Journal:  Angew Chem Int Ed Engl       Date:  2014-09-04       Impact factor: 15.336

Review 4.  Discrimination between primary low-grade and high-grade glioma with 11C-methionine PET: a bivariate diagnostic test accuracy meta-analysis.

Authors:  Anna Falk Delgado; Alberto Falk Delgado
Journal:  Br J Radiol       Date:  2018-01-22       Impact factor: 3.039

Review 5.  Value of 11C-methionine PET in imaging brain tumours and metastases.

Authors:  Andor W J M Glaudemans; Roelien H Enting; Mart A A M Heesters; Rudi A J O Dierckx; Ronald W J van Rheenen; Annemiek M E Walenkamp; Riemer H J A Slart
Journal:  Eur J Nucl Med Mol Imaging       Date:  2012-12-12       Impact factor: 9.236

6.  Preclinical evaluation of an 18F-trifluoroborate methionine derivative for glioma imaging.

Authors:  Xiangyu Yang; Zhibo Liu; Huimin Zhang; Zhu Li; Jeeva P Munasinghe; Gang Niu; Gaojun Teng; Xiaoyuan Chen
Journal:  Eur J Nucl Med Mol Imaging       Date:  2017-12-29       Impact factor: 9.236

Review 7.  From the clinician's point of view - What is the status quo of positron emission tomography in patients with brain tumors?

Authors:  Norbert Galldiks; Karl-Josef Langen; Whitney B Pope
Journal:  Neuro Oncol       Date:  2015-06-30       Impact factor: 12.300

8.  Evaluation of F-18-labeled amino acid derivatives and [18F]FDG as PET probes in a brain tumor-bearing animal model.

Authors:  Hsin-Ell Wang; Shih-Yen Wu; Chi-Wei Chang; Ren-Shen Liu; Li-Chung Hwang; Te-Wei Lee; Jyh-Cheng Chen; Jeng-Jong Hwang
Journal:  Nucl Med Biol       Date:  2005-05       Impact factor: 2.408

Review 9.  The use of amino acid PET and conventional MRI for monitoring of brain tumor therapy.

Authors:  Norbert Galldiks; Ian Law; Whitney B Pope; Javier Arbizu; Karl-Josef Langen
Journal:  Neuroimage Clin       Date:  2016-12-18       Impact factor: 4.881

10.  Boramino acid as a marker for amino acid transporters.

Authors:  Zhibo Liu; Haojun Chen; Kai Chen; Yihan Shao; Dale O Kiesewetter; Gang Niu; Xiaoyuan Chen
Journal:  Sci Adv       Date:  2015-09-11       Impact factor: 14.136
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