Literature DB >> 29339865

Response of Scoliosis in Children with Myelomeningocele to Surgical Release of Tethered Spinal Cord.

Haluk Altiok1,2, Anne Riordan1, Adam Graf1, Joe Krzak1, Sahar Hassani1.   

Abstract

Objective: To examine the effect of surgical tethered cord release (TCR) on scoliosis in children with myelomeningocele.
Methods: A retrospective review of 65 pediatric patients with myelomeningocele and TCR. The final sample consisted of 20 patients with scoliosis who were managed conservatively after TCR.
Results: Average age at TCR was 6.2 years with average follow-up of 3.8 years. Scoliosis of 1 (5%) patient improved, 7 (35%) were stable, and 12 (60%) worsened (≥10°). Fifty percent of patients ultimately required definitive spinal surgery. TCR release delayed definitive spine surgery for an average of 3.2 years. Sixty-four percent of patients with curves less than or equal to 45° had progression of their curves compared to 50% with curves greater than 45°. For patients with curves less than or equal to 45°, curves progressed in 80% of those younger than 10 years as compared to 25% of those older than 10 years. For patients with curves less than or equal to 45°, 43% required definitive spine surgery as opposed to 83% with curves greater than 45°. Level of neurological involvement (ie, lumbar versus thoracic) and age at untethering emerged as factors influencing the effects of TCR for patients with curves less than or equal to 45°. Lumbar curves had more favorable results.
Conclusion: Pediatric patients with myelomeningocele and scoliosis should be closely assessed and monitored. A selective approach for youth with lumbosacral level myelomeningocele and progressive curves less than or equal to 45° may result in scoliosis stabilization and avoidance of definitive surgery.

Entities:  

Keywords:  myelomeningocele; scoliosis; tethered cord

Mesh:

Year:  2016        PMID: 29339865      PMCID: PMC5108508          DOI: 10.1310/sci2204-247

Source DB:  PubMed          Journal:  Top Spinal Cord Inj Rehabil        ISSN: 1082-0744


  20 in total

1.  Natural history of tethered cord in patients with meningomyelocele.

Authors:  Loi K Phuong; Kimberly A Schoeberl; Corey Raffel
Journal:  Neurosurgery       Date:  2002-05       Impact factor: 4.654

2.  Tethered cord syndrome in low motor level children with myelomeningocele.

Authors:  J F Sarwark; D T Weber; A P Gabrieli; D G McLone; L Dias
Journal:  Pediatr Neurosurg       Date:  1996-12       Impact factor: 1.162

3.  The effect of tethered cord release on scoliosis in myelomeningocele.

Authors:  K Pierz; J Banta; J Thomson; N Gahm; J Hartford
Journal:  J Pediatr Orthop       Date:  2000 May-Jun       Impact factor: 2.324

Review 4.  Congenital and developmental deformities of the spine in children with myelomeningocele.

Authors:  James T Guille; John F Sarwark; Henry H Sherk; S Jay Kumar
Journal:  J Am Acad Orthop Surg       Date:  2006-05       Impact factor: 3.020

Review 5.  Orthopedic management of spina bifida.

Authors:  Jeffrey D Thomson; Lee S Segal
Journal:  Dev Disabil Res Rev       Date:  2010

6.  Clinical and radiographic predictors of scoliosis in patients with myelomeningocele.

Authors:  Jayesh Trivedi; Jeffrey D Thomson; Joseph B Slakey; John V Banta; Peter W Jones
Journal:  J Bone Joint Surg Am       Date:  2002-08       Impact factor: 5.284

7.  Pediatric tethered cord syndrome: response of scoliosis to untethering procedures. Clinical article.

Authors:  Matthew J McGirt; Vivek Mehta; Giannina Garces-Ambrossi; Oren Gottfried; Can Solakoglu; Ziya L Gokaslan; Amer Samdani; George I Jallo
Journal:  J Neurosurg Pediatr       Date:  2009-09       Impact factor: 2.375

8.  Scoliosis and hydrocephalus in myelocele patients. The effects of ventricular shunting.

Authors:  P Hall; R Lindseth; R Campbell; J E Kalsbeck; A Desousa
Journal:  J Neurosurg       Date:  1979-02       Impact factor: 5.115

9.  Change in spinal curvature following release of tethered spinal cord associated with spina bifida.

Authors:  D H Reigel; K Tchernoukha; B Bazmi; R Kortyna; D Rotenstein
Journal:  Pediatr Neurosurg       Date:  1994       Impact factor: 1.162

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  4 in total

Review 1.  Is detethering necessary before deformity correction in congenital scoliosis associated with tethered cord syndrome: a meta-analysis of current evidence.

Authors:  Kaustubh Ahuja; Syed Ifthekar; Samarth Mittal; Gagandeep Yadav; P Venkata Sudhakar; Sitanshu Barik; Pankaj Kandwal
Journal:  Eur Spine J       Date:  2020-11-17       Impact factor: 3.134

2.  Reduced complication rate with simultaneous detethering and spinal deformity correction surgery compared to staged surgeries in patients with early onset scoliosis.

Authors:  Jennifer Kunes; Theodore Quan; Rajiv Iyer; Adam N Fano; Hiroko Matsumoto; Mark Erickson; Richard McCarthy; Douglas Brockmeyer; Richard C E Anderson; Michael G Vitale
Journal:  Spine Deform       Date:  2022-07-12

3.  Evaluating the Efficacy of Rib-to-pelvis Growth-friendly Surgery for the Treatment of Non-ambulatory Early-Onset Scoliosis Myelomeningocele Patients.

Authors:  Norman Ramirez; Gerardo Olivella; Ryan E Fitzgerald; John T Smith; Peter F Sturm; Paul D Sponseller; Lawrence I Karlin; Scott J Luhmann; Norberto J Torres-Lugo; Tricia St Hilaire
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2022-05-01

Review 4.  Orthopedic management of myelomeningocele with a multidisciplinary approach: a systematic review of the literature.

Authors:  Ana Presedo; Amirali Karimi; Parnian Shobeiri; Sara Momtazmanesh; Fardis Vosoughi; Mohammad Hossein Nabian
Journal:  J Orthop Surg Res       Date:  2021-08-13       Impact factor: 2.359

  4 in total

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