J Bousquet1,2,3, P Devillier4, S Arnavielhe5, A Bedbrook1, G Alexis-Alexandre6, M van Eerd7, R Murray8, G W Canonica9, M Illario10, E Menditto11, G Passalacqua9, C Stellato12, M Triggiani12, P Carreiro-Martins13, J Fonseca14,15, M Morais Almeida16, L Nogueira-Silva17, A M Pereira15,18,19, A Todo Bom20, I Bosse21, D Caimmi22, P Demoly22, J F Fontaine23, J Just24, G L Onorato1, M L Kowalski25,26, P Kuna27, B Samolinski28, J M Anto29,30,31,32, J Mullol16, A Valero33, P V Tomazic34, K C Bergmann35, T Keil36,37, L Klimek38, R Mösges39,40, S Shamai39,40, T Zuberbier35, E Murphy41, P McDowall41, D Price42,43,44, D Ryan45, A Sheikh46, N H Chavannes47, W J Fokkens48, V Kvedariene49, A Valiulis50,51, C Bachert52, P W Hellings3,53,54, I Kull55, E Melen55, M Wickman56,57, C Bindslev-Jensen58, E Eller58, T Haahtela59, N G Papadopoulos60,61, I Annesi-Maesano62,63, M Bewick64, S Bosnic-Anticevich65,66, A A Cruz67,68, G De Vries7, B Gemicioglu69, D Larenas-Linnemann70, D Laune5, E Mathieu-Dupas5, R E O'Hehir71,72, O Pfaar38,73, F Portejoie1, V Siroux74, O Spranger75, E Valovirta76, O VandenPlas77, A Yorgancioglu78. 1. Contre les MAladies Chroniques Pour un VIeillissement Actif en France, European Innovation Partnership on Active and Healthy Ageing Reference Site, MACVIA-France, Montpellier, France. 2. INSERM U 1168, VIMA: Ageing and Chronic Diseases Epidemiological and Public Health Approaches, Université Versailles St-Quentin-en-Yvelines, UMR-S168, Villejuif, Montigny le Bretonneux, France. 3. Euforea, Brussels, Belgium. 4. Laboratoire de Pharmacologie Respiratoire UPRES EA220, Pôle des Maladies Respiratoires, Hôpital Foch, Suresnes - Université Versailles Saint-Quentin, Versailles, France. 5. Kyomed, Montpellier, France. 6. EZY, Montpellier, France. 7. Peercode BV, Gerdermalsen, The Netherlands. 8. Medical Communications Consultant, MedScript Ltd, Dundalk, Ireland. 9. Allergy and Respiratory Diseases, Department of Internal Medicine, IRCCS San Martino-IST-University of Genoa, Genoa, Italy. 10. Division for Health Innovation, Campania Region and Federico II University Hospital Naples (R&D and DISMET), Naples, Italy. 11. Center of Pharmacoeconomics, CIRFF, University of Naples Federico II, Naples, Italy. 12. Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy. 13. Servicio de Imunoalergologia, EPE - Nova Medical School, Respiratory Research Group, CEDOC, Centro Hospitalar de Lisboa Central, Lisbon, Portugal. 14. Faculdade de Medicina, Center for Health Technology and Services Research-CINTESIS, Universidade do Porto, Porto, Portugal. 15. Allergy Unit, CUF Porto Instituto & Hospital, Porto, Portugal. 16. Rhinology Unit & Smell Clinic, ENT Department, Hospital Clinic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain. 17. Department of Internal Medicine, Center for Health Technology and Services Research-CINTESIS, Centro Hospitalar Sao Joao, Porto, Portugal. 18. Immunoallergy Department, CUF-Descobertas Hospital, Lisbon, Portugal. 19. Health Information and Decision Sciences Department, Faculty of Medicine of the University of Porto, Porto, Portugal. 20. Imunoalergologia, Centro Hospitalar Universitario de Coimbra, Faculty of Medicine, University of Coimbra, Coimbra, Portugal. 21. Allergist, La Rochelle, France. 22. CHU de Montpellier, UPMC, Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Sorbonne Universités, Paris, France. 23. Allergist, Reims, France. 24. Allergology Department, Centre de l'Asthme et des Allergies, Hôpital d'Enfants Armand-Trousseau - INSERM, UMRS 1136, UPMC Univ Paris 06 - Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe EPAR, Sorbonne Universités, Paris, France. 25. Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz, Poland. 26. HARC, Lodz, Poland. 27. Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland. 28. Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland. 29. ISGLoBAL, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain. 30. IMIM (Hospital del Mar Research Institute), Barcelona, Spain. 31. CIBER Epidemiologıa y Salud Publica (CIBERESP), Barcelona, Spain. 32. Universitat Pompeu Fabra (UPF), Barcelona, Spain. 33. Pneumology and Allergy Department Hospital Clınic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain. 34. Department of ENT, Medical University of Graz, Graz, Austria. 35. Comprehensive Allergy-Centre-Charité, Department of Dermatology and Allergy, Global Allergy and Asthma European Network (GA2LEN), Charité Universitatsmedizin Berlin, Berlin, Germany. 36. Institute of Social Medicine, Epidemiology and Health Economics, Charité-Universitatsmedizin, Berlin, Germany. 37. Institute for Clinical Epidemiology and Biometry, University of Wuerzburg, Wuerzburg, Germany. 38. Center for Rhinology and Allergology, Wiesbaden, Germany. 39. Institute of Medical Statistics and Computational Biology, Medical Faculty, University of Cologne, Cologne, Germany. 40. CRI-Clinical Research International-Ltd, Hamburg, Germany. 41. Newcastle OHS, The Newcastle upon Tyne NHS Foundation Hospitals Trust, Newcastle upon Tyne, UK. 42. Observational and Pragmatic Research Institute, Singapore City, Singapore. 43. Optimum Patient Care, Cambridge, UK. 44. Academic Centre of Primary Care, University of Aberdeen, Aberdeen, UK. 45. Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK. 46. Asthma UK Centre for Applied Research, Centre of Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK. 47. Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands. 48. Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands. 49. Clinic of Infectious, Chest Diseases, Dermatology and Allergology, Vilnius University, Vilnius, Lithuania. 50. Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius, Lithuania. 51. European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium. 52. ENT Department, Upper Airways Research Laboratory, Ghent University Hospital, Ghent, Belgium. 53. Department of Otorhinolaryngology-Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium. 54. Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. 55. Department of Clinical Science and Education, Sodersjukhuset, Karolinska Institutet, Stockholm, Sweden. 56. Sodersjukhuset, Sachs' Children and Youth Hospital, Stockholm, Sweden. 57. Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. 58. Department of Dermatology and Allergy Centre, Odense Research Center for Anaphylaxis (ORCA), Odense University Hospital, Odense, Denmark. 59. Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland. 60. Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children's Hospital, University of Manchester, Manchester, UK. 61. Allergy Department, 2nd Pediatric Clinic, Athens General Children's Hospital "P&A Kyriakou", University of Athens, Athens, Greece. 62. EPAR U707 INSERM, Paris, France. 63. EPAR UMR-S UPMC, Paris VI, Paris, France. 64. i Q4U Consultants Ltd, London, UK. 65. Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia. 66. Sydney Local Health District, Glebe, NSW, Australia. 67. ProAR-Nucleo de Excelencia em Asma, Federal University of Bahia, Salvador, Brazil. 68. GARD Executive Committee, Salvador, Brazil. 69. Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey. 70. Center of Excellence in Asthma and Allergy, Hospital Médica Sur, Mexico City, Mexico. 71. Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic., Australia. 72. Department of Immunology, Monash University, Melbourne, Vic., Australia. 73. Departent of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannhein, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. 74. INSERM, Universite Grenoble Alpes, IAB, U 1209, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Université Joseph Fourier, Grenoble, France. 75. Global Allergy and Asthma Platform GAAPP, Vienna, Austria. 76. Department of Lung Diseases and Clinical Allergology, Terveystalo, Allergy Clinic, University of Turku, Turku, Finland. 77. Department of Chest Medicine, Centre Hospitalier Universitaire UCL Namur, Université Catholique de Louvain, Yvoir, Belgium. 78. Department of Pulmonology, Celal Bayar University, Manisa, Turkey.
Abstract
BACKGROUND: Large observational implementation studies are needed to triangulate the findings from randomized control trials as they reflect "real-world" everyday practice. In a pilot study, we attempted to provide additional and complementary insights on the real-life treatment of allergic rhinitis (AR) using mobile technology. METHODS: A mobile phone app (Allergy Diary, freely available in Google Play and Apple App stores) collects the data of daily visual analog scales (VAS) for (i) overall allergic symptoms, (ii) nasal, ocular, and asthma symptoms, (iii) work, as well as (iv) medication use using a treatment scroll list including all medications (prescribed and over the counter (OTC)) for rhinitis customized for 15 countries. RESULTS: A total of 2871 users filled in 17 091 days of VAS in 2015 and 2016. Medications were reported for 9634 days. The assessment of days appeared to be more informative than the course of the treatment as, in real life, patients do not necessarily use treatment on a daily basis; rather, they appear to increase treatment use with the loss of symptom control. The Allergy Diary allowed differentiation between treatments within or between classes (intranasal corticosteroid use containing medications and oral H1-antihistamines). The control of days differed between no [best control], single, or multiple treatments (worst control). CONCLUSIONS: This study confirms the usefulness of the Allergy Diary in accessing and assessing everyday use and practice in AR. This pilot observational study uses a very simple assessment (VAS) on a mobile phone, shows novel findings, and generates new hypotheses.
BACKGROUND: Large observational implementation studies are needed to triangulate the findings from randomized control trials as they reflect "real-world" everyday practice. In a pilot study, we attempted to provide additional and complementary insights on the real-life treatment of allergic rhinitis (AR) using mobile technology. METHODS: A mobile phone app (Allergy Diary, freely available in Google Play and Apple App stores) collects the data of daily visual analog scales (VAS) for (i) overall allergic symptoms, (ii) nasal, ocular, and asthma symptoms, (iii) work, as well as (iv) medication use using a treatment scroll list including all medications (prescribed and over the counter (OTC)) for rhinitis customized for 15 countries. RESULTS: A total of 2871 users filled in 17 091 days of VAS in 2015 and 2016. Medications were reported for 9634 days. The assessment of days appeared to be more informative than the course of the treatment as, in real life, patients do not necessarily use treatment on a daily basis; rather, they appear to increase treatment use with the loss of symptom control. The Allergy Diary allowed differentiation between treatments within or between classes (intranasal corticosteroid use containing medications and oral H1-antihistamines). The control of days differed between no [best control], single, or multiple treatments (worst control). CONCLUSIONS: This study confirms the usefulness of the Allergy Diary in accessing and assessing everyday use and practice in AR. This pilot observational study uses a very simple assessment (VAS) on a mobile phone, shows novel findings, and generates new hypotheses.
Authors: Ayşe Arzu Yorgancıoğlu; Bilun Gemicioğlu; Cemal Cingi; Ömer Kalaycı; Ali Fuat Kalyoncu; Claus Bachert; Peter Hellings; Oliver Pfaar; Holger J Schünemann; Dana Wallace; Anna Bedbrook; Wienczyslawa Czarlewski; Jean Bousquet Journal: Turk Thorac J Date: 2020-03-01
Authors: Jean Bousquet; Josep M Anto; Isabella Annesi-Maesano; Toni Dedeu; Eve Dupas; Jean-Louis Pépin; Landry Stephane Zeng Eyindanga; Sylvie Arnavielhe; Julia Ayache; Xavier Basagana; Samuel Benveniste; Nuria Calves Venturos; Hing Kin Chan; Mehdi Cheraitia; Yves Dauvilliers; Judith Garcia-Aymerich; Ingrid Jullian-Desayes; Chitra Dinesh; Daniel Laune; Jade Lu Dac; Ismael Nujurally; Giovanni Pau; Robert Picard; Xavier Rodo; Renaud Tamisier; Michael Bewick; Nils E Billo; Wienczyslawa Czarlewski; Joao Fonseca; Ludger Klimek; Oliver Pfaar; Jean-Marc Bourez Journal: Clin Transl Allergy Date: 2018-09-17 Impact factor: 5.871
Authors: J Bousquet; A Bedbrook; W Czarlewski; G L Onorato; S Arnavielhe; D Laune; E Mathieu-Dupas; J Fonseca; E Costa; O Lourenço; M Morais-Almeida; A Todo-Bom; M Illario; E Menditto; G W Canonica; L Cecchi; R Monti; L Napoli; M T Ventura; G De Feo; W J Fokkens; N H Chavannes; S Reitsma; A A Cruz; J da Silva; F S Serpa; D Larenas-Linnemann; J M Fuentes Perez; Y R Huerta-Villalobos; D Rivero-Yeverino; E Rodriguez-Zagal; A Valiulis; R Dubakiene; R Emuzyte; V Kvedariene; I Annesi-Maesano; H Blain; P Bonniaud; I Bosse; Y Dauvilliers; P Devillier; J F Fontaine; J L Pépin; N Pham-Thi; F Portejoie; R Picard; N Roche; C Rolland; P Schmidt-Grendelmeier; P Kuna; B Samolinski; J M Anto; V Cardona; J Mullol; H Pinnock; D Ryan; A Sheikh; S Walker; S Williams; S Becker; L Klimek; O Pfaar; K C Bergmann; R Mösges; T Zuberbier; R E Roller-Wirnsberger; P V Tomazic; T Haahtela; J Salimäki; S Toppila-Salmi; E Valovirta; T Vasankari; B Gemicioğlu; A Yorgancioglu; N G Papadopoulos; E P Prokopakis; I G Tsiligianni; S Bosnic-Anticevich; R O'Hehir; J C Ivancevich; H Neffen; M E Zernotti; I Kull; E Melén; M Wickman; C Bachert; P W Hellings; G Brusselle; S Palkonen; C Bindslev-Jensen; E Eller; S Waserman; L P Boulet; J Bouchard; D K Chu; H J Schünemann; M Sova; G De Vries; M van Eerd; I Agache; I J Ansotegui; M Bewick; T Casale; M Dykewick; M Ebisawa; R Murray; R Naclerio; Y Okamoto; D V Wallace Journal: Clin Transl Allergy Date: 2019-03-11 Impact factor: 5.871
Authors: J Jean Bousquet; Holger J Schünemann; Alkis Togias; Marina Erhola; Peter W Hellings; Torsten Zuberbier; Ioana Agache; Ignacio J Ansotegui; Josep M Anto; Claus Bachert; Sven Becker; Martin Bedolla-Barajas; Michael Bewick; Sinthia Bosnic-Anticevich; Isabelle Bosse; Louis P Boulet; Jean Marc Bourrez; Guy Brusselle; Niels Chavannes; Elisio Costa; Alvaro A Cruz; Wienczyslawa Czarlewski; Wytske J Fokkens; Joao A Fonseca; Mina Gaga; Tari Haahtela; Maddalena Illario; Ludger Klimek; Piotr Kuna; Violeta Kvedariene; L T T Le; Desiree Larenas-Linnemann; Daniel Laune; Olga M Lourenço; Enrica Menditto; Joaquin Mullol; Yashitaka Okamoto; Nikos Papadopoulos; Nhân Pham-Thi; Robert Picard; Hilary Pinnock; Nicolas Roche; Regina E Roller-Wirnsberger; Christine Rolland; Boleslaw Samolinski; Aziz Sheikh; Sanna Toppila-Salmi; Ioanna Tsiligianni; Arunas Valiulis; Erkka Valovirta; Tuula Vasankari; Maria-Teresa Ventura; Samantha Walker; Sian Williams; Cezmi A Akdis; Isabella Annesi-Maesano; Sylvie Arnavielhe; Xavier Basagana; Eric Bateman; Anna Bedbrook; K S Bennoor; Samuel Benveniste; Karl C Bergmann; Slawomir Bialek; Nils Billo; Carsten Bindslev-Jensen; Leif Bjermer; Hubert Blain; Mateo Bonini; Philippe Bonniaud; Jacques Bouchard; Vitalis Briedis; Christofer E Brightling; Jan Brozek; Roland Buhl; Roland Buonaiuto; Giorgo W Canonica; Victoria Cardona; Ana M Carriazo; Warner Carr; Christine Cartier; Thomas Casale; Lorenzo Cecchi; Alfonso M Cepeda Sarabia; Eka Chkhartishvili; Derek K Chu; Cemal Cingi; Elaine Colgan; Jaime Correia de Sousa; Anne Lise Courbis; Adnan Custovic; Biljana Cvetkosvki; Gennaro D'Amato; Jane da Silva; Carina Dantas; Dejand Dokic; Yves Dauvilliers; Antoni Dedeu; Giulia De Feo; Philippe Devillier; Stefania Di Capua; Marc Dykewickz; Ruta Dubakiene; Motohiro Ebisawa; Yaya El-Gamal; Esben Eller; Regina Emuzyte; John Farrell; Antjie Fink-Wagner; Alessandro Fiocchi; Jean F Fontaine; Bilun Gemicioğlu; Peter Schmid-Grendelmeir; Amiran Gamkrelidze; Judith Garcia-Aymerich; Maximiliano Gomez; Sandra González Diaz; Maia Gotua; Nick A Guldemond; Maria-Antonieta Guzmán; Jawad Hajjam; John O'B Hourihane; Marc Humbert; Guido Iaccarino; Despo Ierodiakonou; Maddalena Illario; Juan C Ivancevich; Guy Joos; Ki-Suck Jung; Marek Jutel; Igor Kaidashev; Omer Kalayci; Przemyslaw Kardas; Thomas Keil; Mussa Khaitov; Nikolai Khaltaev; Jorg Kleine-Tebbe; Marek L Kowalski; Vicky Kritikos; Inger Kull; Lisa Leonardini; Philip Lieberman; Brian Lipworth; Karin C Lodrup Carlsen; Claudia C Loureiro; Renaud Louis; Alpana Mair; Gert Marien; Bassam Mahboub; Joao Malva; Patrick Manning; Esteban De Manuel Keenoy; Gailen D Marshall; Mohamed R Masjedi; Jorge F Maspero; Eve Mathieu-Dupas; Poalo M Matricardi; Eric Melén; Elisabete Melo-Gomes; Eli O Meltzer; Enrica Menditto; Jacques Mercier; Neven Miculinic; Florin Mihaltan; Branislava Milenkovic; Giuliana Moda; Maria-Dolores Mogica-Martinez; Yousser Mohammad; Steve Montefort; Ricardo Monti; Mario Morais-Almeida; Ralf Mösges; Lars Münter; Antonella Muraro; Ruth Murray; Robert Naclerio; Luigi Napoli; Leila Namazova-Baranova; Hugo Neffen; Kristoff Nekam; Angelo Neou; Enrico Novellino; Dieudonné Nyembue; Robin O'Hehir; Ken Ohta; Kimi Okubo; Gabrielle Onorato; Solange Ouedraogo; Isabella Pali-Schöll; Susanna Palkonen; Peter Panzner; Hae-Sim Park; Jean-Louis Pépin; Ana-Maria Pereira; Oliver Pfaar; Ema Paulino; Jim Phillips; Robert Picard; Davor Plavec; Ted A Popov; Fabienne Portejoie; David Price; Emmanuel P Prokopakis; Benoit Pugin; Filip Raciborski; Rojin Rajabian-Söderlund; Sietze Reitsma; Xavier Rodo; Antonino Romano; Nelson Rosario; Menahenm Rottem; Dermot Ryan; Johanna Salimäki; Mario M Sanchez-Borges; Juan-Carlos Sisul; Dirceu Solé; David Somekh; Talant Sooronbaev; Milan Sova; Otto Spranger; Cristina Stellato; Rafael Stelmach; Charlotte Suppli Ulrik; Michel Thibaudon; Teresa To; Ana Todo-Bom; Peter V Tomazic; Antonio A Valero; Rudolph Valenta; Marylin Valentin-Rostan; Rianne van der Kleij; Olivier Vandenplas; Giorgio Vezzani; Frédéric Viart; Giovanni Viegi; Dana Wallace; Martin Wagenmann; De Y Wang; Susan Waserman; Magnus Wickman; Dennis M Williams; Gary Wong; Piotr Wroczynski; Panayiotis K Yiallouros; Arzu Yorgancioglu; Osman M Yusuf; Heahter J Zar; Stéphane Zeng; Mario Zernotti; Luo Zhang; Nan S Zhong; Mihaela Zidarn Journal: Clin Transl Allergy Date: 2019-09-09 Impact factor: 5.871
Authors: J Bousquet; S Arnavielhe; A Bedbrook; M Bewick; D Laune; E Mathieu-Dupas; R Murray; G L Onorato; J L Pépin; R Picard; F Portejoie; E Costa; J Fonseca; O Lourenço; M Morais-Almeida; A Todo-Bom; A A Cruz; J da Silva; F S Serpa; M Illario; E Menditto; L Cecchi; R Monti; L Napoli; M T Ventura; G De Feo; D Larenas-Linnemann; M Fuentes Perez; Y R Huerta Villabolos; D Rivero-Yeverino; E Rodriguez-Zagal; F Amat; I Annesi-Maesano; I Bosse; P Demoly; P Devillier; J F Fontaine; J Just; T P Kuna; B Samolinski; A Valiulis; R Emuzyte; V Kvedariene; D Ryan; A Sheikh; P Schmidt-Grendelmeier; L Klimek; O Pfaar; K C Bergmann; R Mösges; T Zuberbier; R E Roller-Wirnsberger; P Tomazic; W J Fokkens; N H Chavannes; S Reitsma; J M Anto; V Cardona; T Dedeu; J Mullol; T Haahtela; J Salimäki; S Toppila-Salmi; E Valovirta; B Gemicioğlu; A Yorgancioglu; N Papadopoulos; E P Prokopakis; S Bosnic-Anticevich; R O'Hehir; J C Ivancevich; H Neffen; E Zernotti; I Kull; E Melen; M Wickman; C Bachert; P Hellings; S Palkonen; C Bindslev-Jensen; E Eller; S Waserman; M Sova; G De Vries; M van Eerd; I Agache; T Casale; M Dykewickz; R N Naclerio; Y Okamoto; D V Wallace Journal: Clin Transl Allergy Date: 2018-10-25 Impact factor: 5.871
Authors: A Valiulis; J Bousquet; A Veryga; U Suprun; D Sergeenko; S Cebotari; D Borelli; S Pietikainen; J Banys; I Agache; N E Billo; A Bush; I Chkhaidze; L Dubey; W J Fokkens; J Grigg; T Haahtela; K Julge; O Katilov; N Khaltaev; M Odemyr; S Palkonen; R Savli; A Utkus; V Vilc; T Alasevicius; A Bedbrook; M Bewick; J Chorostowska-Wynimko; E Danila; A Hadjipanayis; R Karseladze; V Kvedariene; E Lesinskas; L Münter; B Samolinski; S Sargsyan; B Sitkauskiene; D Somekh; L Vaideliene; A Valiulis; P W Hellings Journal: Clin Transl Allergy Date: 2019-01-28 Impact factor: 5.871