S Henni1, Y W Semporé2, T Le Meliner1, N Ouedraogo2, J-F Hamel3, P Abraham4. 1. Laboratoire d'explorations fonctionnelles vasculaires, CHU d'Angers, France. 2. Laboratoire d'explorations fonctionnelles vasculaires, CHU d'Angers, France; Laboratoire de Physiologie, Institut Supérieur des Sciences de la Santé, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso. 3. Département de bio statistiques, CHU d'Angers, France. 4. Laboratoire d'explorations fonctionnelles vasculaires, CHU d'Angers, France; Unité mixte de recherche INSERM 1083- CNRS 6015, Faculté de Médecine, Angers, France. Electronic address: piabraham@chu-angers.fr.
Abstract
BACKGROUND: Transcutaneous oxygen pressure (tcpO2) reliability is blunted by an unpredictable transcutaneous gradient through the skin. We hypothesized that the "Decrease from Rest of Oxygen pressure (DROP: subtraction of limb-changes from chest-changes from the respective starting values) would show a good to excellent reliability during Exercise -tcpO2 investigations. METHODS: In three different experiments we tested: The intra-test variability at the peripheral level (Experiment A: 32 patients, 16 at each location), at the chest level (Experiment B: 45 patients) and the test-retest reproducibility within 3 months (Experiment C: 67 patients). We calculated the intra-class coefficient of correlation (ICC) with 95% confidence interval [Lower/upper limit]. ICC between 0.60 and 0.749 indicate a good agreement. ICC above 0.750 indicates an excellent agreement. RESULTS: ICC values for DROP-min were 0.848 [0.723/0.935] at the buttock and 0.920 [0.846/0.967] at the calf levels, in experiment A; ICC were 0.873 [0.799/0.923] at the buttock and 0.898 [0.790/0.953] at the calf levels, in experiment B; 0.806 [0.716/0.871] at then buttock level (n = 67) and 0.807 [0.722/0.868] at the calf in experiment C. CONCLUSIONS: Intra-test and test-retest reliability is excellent using the DROP calculation for exercise-tcpO2 investigations.
BACKGROUND: Transcutaneous oxygen pressure (tcpO2) reliability is blunted by an unpredictable transcutaneous gradient through the skin. We hypothesized that the "Decrease from Rest of Oxygen pressure (DROP: subtraction of limb-changes from chest-changes from the respective starting values) would show a good to excellent reliability during Exercise -tcpO2 investigations. METHODS: In three different experiments we tested: The intra-test variability at the peripheral level (Experiment A: 32 patients, 16 at each location), at the chest level (Experiment B: 45 patients) and the test-retest reproducibility within 3 months (Experiment C: 67 patients). We calculated the intra-class coefficient of correlation (ICC) with 95% confidence interval [Lower/upper limit]. ICC between 0.60 and 0.749 indicate a good agreement. ICC above 0.750 indicates an excellent agreement. RESULTS: ICC values for DROP-min were 0.848 [0.723/0.935] at the buttock and 0.920 [0.846/0.967] at the calf levels, in experiment A; ICC were 0.873 [0.799/0.923] at the buttock and 0.898 [0.790/0.953] at the calf levels, in experiment B; 0.806 [0.716/0.871] at then buttock level (n = 67) and 0.807 [0.722/0.868] at the calf in experiment C. CONCLUSIONS: Intra-test and test-retest reliability is excellent using the DROP calculation for exercise-tcpO2 investigations.
Authors: O Stivalet; A Paisant; D Belabbas; L Omarjee; A Le Faucheur; P Landreau; R Garlantezec; V Jaquinandi; D A Liedl; P W Wennberg; G Mahé Journal: PLoS One Date: 2019-06-27 Impact factor: 3.240
Authors: Jeanne Hersant; Simon Lecoq; Pierre Ramondou; Xavier Papon; Mathieu Feuilloy; Pierre Abraham; Samir Henni Journal: Front Physiol Date: 2022-02-11 Impact factor: 4.566
Authors: Simone F Kleiss; Kirsten F Ma; Mostafa El Moumni; Richte C L Schuurmann; Clark J Zeebregts; Marieke Haalboom; Reinoud P H Bokkers; Jean-Paul P M de Vries Journal: J Clin Monit Comput Date: 2021-04-12 Impact factor: 1.977