| Literature DB >> 29316212 |
Spyros Stratigis1, Kostas Stylianou1, Periklis P Kyriazis2, Eleftheria-Kleio Dermitzaki1, Dimitra Lygerou1, Paraskevi Syngelaki1, Stavros Stratakis1, Sophia Koukouraki3, Fragiskos Parthenakis4, Dimitrios Tsetis5, Eugene Daphnis1.
Abstract
The authors evaluated the effectiveness of percutaneous renal revascularization (PRR) with stenting for the treatment of atherosclerotic renal artery stenosis (ARAS) in patients with coronary artery disease and the usefulness of captopril renal scintigraphy for predicting clinical outcomes after PRR. Sixty-four consecutive patients, referred for evaluation of suspected ARAS, after coronary angiography, underwent baseline captopril renal scintigraphy followed by renal angiography. Forty-four patients (68.7%) were diagnosed with a significant ARAS≥ 60% and were treated with PRR plus medical therapy. Twenty-four months after PRR, 86.4% and 73.3% of patients showed a hypertension and renal benefit, respectively. Captopril renal scintigraphy positivity had moderate sensitivity and high specificity in predicting a hypertension and renal benefit. In patients with ARAS≥ 70%, the sensitivity and specificity were 100% for both a hypertension and renal benefit.PRR for ARAS conferred a substantial benefit in patients with a high coronary artery disease burden. Captopril renal scintigraphy was highly accurate in predicting clinical outcomes. ©2018 Wiley Periodicals, Inc.Entities:
Keywords: captopril renal scintigraphy; percutaneous renal revascularization; renal artery stenosis; renovascular hypertension
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Year: 2018 PMID: 29316212 PMCID: PMC8030775 DOI: 10.1111/jch.13160
Source DB: PubMed Journal: J Clin Hypertens (Greenwich) ISSN: 1524-6175 Impact factor: 3.738