Máté Kiss1,2,3, Petra Hermann4, Zoltán Vidnyánszky4, Viktor Gál4. 1. Brain Imaging Centre, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2, Budapest, 1117, Hungary. kiss.mate@ttk.mta.hu. 2. János Szentágothai PhD School, MR Research Centre, Balassa Street 6, Budapest, 1083, Hungary. kiss.mate@ttk.mta.hu. 3. Department of Neuroradiology, National Institute of Clinical Neuroscience, Amerikai Street 57, Budapest, 1145, Hungary. kiss.mate@ttk.mta.hu. 4. Brain Imaging Centre, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2, Budapest, 1117, Hungary.
Abstract
PURPOSE: To maintain alertness and to remain motionless during scanning represent a substantial challenge for patients/subjects involved in both clinical and research functional magnetic resonance imaging (fMRI) examinations. Therefore, availability and application of new data acquisition protocols allowing the shortening of scan time without compromising the data quality and statistical power are of major importance. METHODS: Higher order category-selective visual cortical areas were identified individually, and rapid event-related fMRI design was used to compare three different sampling rates (TR = 2000, 1000, and 410 ms, using state-of-the-art simultaneous multislice imaging) and four different scanning lengths to match the statistical power of the traditional scanning methods to high sampling-rate design. RESULTS: The results revealed that ~ 4 min of the scan time with 1 Hz (TR = 1000 ms) sampling rate and ~ 2 min scanning at ~ 2.5 Hz (TR = 410 ms) sampling rate provide similar localization sensitivity and selectivity to that obtained with 11-min session at conventional, 0.5 Hz (TR = 2000 ms) sampling rate. CONCLUSION: Our findings suggest that task-based fMRI examination of clinical population prone to distress such as presurgical mapping experiments might substantially benefit from the reduced (20-40%) scanning time that can be achieved by the application of simultaneous multislice sequences.
PURPOSE: To maintain alertness and to remain motionless during scanning represent a substantial challenge for patients/subjects involved in both clinical and research functional magnetic resonance imaging (fMRI) examinations. Therefore, availability and application of new data acquisition protocols allowing the shortening of scan time without compromising the data quality and statistical power are of major importance. METHODS: Higher order category-selective visual cortical areas were identified individually, and rapid event-related fMRI design was used to compare three different sampling rates (TR = 2000, 1000, and 410 ms, using state-of-the-art simultaneous multislice imaging) and four different scanning lengths to match the statistical power of the traditional scanning methods to high sampling-rate design. RESULTS: The results revealed that ~ 4 min of the scan time with 1 Hz (TR = 1000 ms) sampling rate and ~ 2 min scanning at ~ 2.5 Hz (TR = 410 ms) sampling rate provide similar localization sensitivity and selectivity to that obtained with 11-min session at conventional, 0.5 Hz (TR = 2000 ms) sampling rate. CONCLUSION: Our findings suggest that task-based fMRI examination of clinical population prone to distress such as presurgical mapping experiments might substantially benefit from the reduced (20-40%) scanning time that can be achieved by the application of simultaneous multislice sequences.
Authors: Jonathan R Polimeni; Himanshu Bhat; Thomas Witzel; Thomas Benner; Thorsten Feiweier; Souheil J Inati; Ville Renvall; Keith Heberlein; Lawrence L Wald Journal: Magn Reson Med Date: 2015-03-23 Impact factor: 4.668
Authors: Cornelius Eichner; Kourosh Jafari-Khouzani; Stephen Cauley; Himanshu Bhat; Pavlina Polaskova; Ovidiu C Andronesi; Otto Rapalino; Robert Turner; Lawrence L Wald; Steven Stufflebeam; Kawin Setsompop Journal: Magn Reson Med Date: 2013-10-28 Impact factor: 4.668
Authors: Tanvi N Nadkarni; Matthew J Andreoli; Veena A Nair; Peng Yin; Brittany M Young; Bornali Kundu; Joshua Pankratz; Andrew Radtke; Ryan Holdsworth; John S Kuo; Aaron S Field; Mustafa K Baskaya; Chad H Moritz; M Elizabeth Meyerand; Vivek Prabhakaran Journal: Neuroimage Clin Date: 2014-12-24 Impact factor: 4.881