| Literature DB >> 29302007 |
Da Yin1, Erich M Schwarz2, Cristel G Thomas1,3, Rebecca L Felde1, Ian F Korf4, Asher D Cutter3, Caitlin M Schartner5, Edward J Ralston5, Barbara J Meyer5, Eric S Haag6.
Abstract
To reveal impacts of sexual mode on genome content, we compared chromosome-scale assemblies of the outcrossing nematode Caenorhabditis nigoni to its self-fertile sibling species, C. briggsaeC. nigoni's genome resembles that of outcrossing relatives but encodes 31% more protein-coding genes than C. briggsaeC. nigoni genes lacking C. briggsae orthologs were disproportionately small and male-biased in expression. These include the male secreted short (mss) gene family, which encodes sperm surface glycoproteins conserved only in outcrossing species. Sperm from mss-null males of outcrossing C. remanei failed to compete with wild-type sperm, despite normal fertility in noncompetitive mating. Restoring mss to C. briggsae males was sufficient to enhance sperm competitiveness. Thus, sex has a pervasive influence on genome content that can be used to identify sperm competition factors.Entities:
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Year: 2018 PMID： 29302007 PMCID： PMC5789457 DOI： 10.1126/science.aao0827
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728