Shuguang Wen1, Wenbiao Ren2, Bichen Xue2, Yi Fan2, Yongjun Jiang1, Chunming Zeng1, Yujia Li1, Xiongbing Zu3. 1. Department of Urology, Central Hospital of Yongzhou, Yongzhou, 425006, China. 2. Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China. 3. Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China. zuxbxyyy@126.com.
Abstract
PURPOSE: To examine the possible prognostic factors in patients with penile cancer after surgical management and to identify the independent predictive factors of the prognosis. MATERIALS AND METHODS: Clinical data of 135 patients with penile cancer who underwent surgical management in two medical centers were collected. Follow-up data were available for 103 patients. Possible prognostic factors including patient's age; smoking or not; course of disease; phimosis or not; type of surgery; tumor stage; nodal stage; tumor grade and pathological lymph nodes metastasis were retrospectively analyzed by univariate and multivariate analyses with Cox regression. RESULTS: Five-year cancer-specific survival (CSS) and 1-year CSS were 88.5 and 98.1%, respectively. Univariate Cox analysis revealed that nodal stage and pathological lymph nodes metastasis were significant prognostic factors. Multivariate Cox analysis revealed pathological lymph nodes metastasis was the independent predictive factor of the prognosis. CONCLUSION: Pathological lymph nodes metastasis is the independent predictive factor worsening the prognosis in patients with penile cancer.
PURPOSE: To examine the possible prognostic factors in patients with penile cancer after surgical management and to identify the independent predictive factors of the prognosis. MATERIALS AND METHODS: Clinical data of 135 patients with penile cancer who underwent surgical management in two medical centers were collected. Follow-up data were available for 103 patients. Possible prognostic factors including patient's age; smoking or not; course of disease; phimosis or not; type of surgery; tumor stage; nodal stage; tumor grade and pathological lymph nodes metastasis were retrospectively analyzed by univariate and multivariate analyses with Cox regression. RESULTS: Five-year cancer-specific survival (CSS) and 1-year CSS were 88.5 and 98.1%, respectively. Univariate Cox analysis revealed that nodal stage and pathological lymph nodes metastasis were significant prognostic factors. Multivariate Cox analysis revealed pathological lymph nodes metastasis was the independent predictive factor of the prognosis. CONCLUSION: Pathological lymph nodes metastasis is the independent predictive factor worsening the prognosis in patients with penile cancer.
Authors: Paweł Wiechno; Tomasz Kalinowski; Bartosz Itrych; Bożena Sikora-Kupis; Tomasz Demkow; Marek Karwański Journal: Urol Int Date: 2013-09-17 Impact factor: 2.089
Authors: Paul K Hegarty; Ian Eardley; Axel Heidenreich; W Scott McDougal; Suks Minhas; Philippe E Spiess; Nick Watkin; Simon Horenblas Journal: BJU Int Date: 2014-10-16 Impact factor: 5.588
Authors: Juan Chipollini; Dominic H Tang; Neil Manimala; Scott M Gilbert; Julio M Pow-Sang; Wade J Sexton; Michael A Poch; Philippe E Spiess Journal: Urol Oncol Date: 2017-10-09 Impact factor: 3.498
Authors: Oliver W Hakenberg; Eva M Compérat; Suks Minhas; Andrea Necchi; Chris Protzel; Nick Watkin Journal: Eur Urol Date: 2014-11-01 Impact factor: 20.096
Authors: Janet R Daling; Margaret M Madeleine; Lisa G Johnson; Stephen M Schwartz; Katherine A Shera; Michelle A Wurscher; Joseph J Carter; Peggy L Porter; Denise A Galloway; James K McDougall; John N Krieger Journal: Int J Cancer Date: 2005-09-10 Impact factor: 7.396
Authors: Suresh K Bhagat; Ganesh Gopalakrishnan; Nitin S Kekre; Ninan K Chacko; Santosh Kumar; M T Manipadam; Prasanna Samuel Journal: World J Urol Date: 2009-06-02 Impact factor: 4.226
Authors: Anita Thomas; Sascha Reetz; Philipp Stenzel; Katrin Tagscherer; Wilfried Roth; Mario Schindeldecker; Martin Michaelis; Florian Rothweiler; Jindrich Cinatl; Jaroslav Cinatl; Robert Dotzauer; Olesya Vakhrusheva; Maarten Albersen; Stephan Macher-Goeppinger; Axel Haferkamp; Eva Juengel; Andreas Neisius; Igor Tsaur Journal: Cancers (Basel) Date: 2021-05-12 Impact factor: 6.639