Naga Venkata Pothineni1, Nishi N Shah1, Yogita Rochlani2, Marwan Saad1, Swathi Kovelamudi1, Konstantinos Marmagkiolis3, Sabha Bhatti1, Mehmet Cilingiroglu4, Wilbert S Aronow2, Abdul Hakeem1,5. 1. Division of Cardiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. 2. Division of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, New York, USA. 3. Department of Cardiology, Florida Hospital, Zephyrhills, Florida, USA. 4. Department of Cardiology, Arkansas Heart Hospital, Little Rock, Arkansas, USA. 5. Division of Cardiovascular Medicine, Department of Internal Medicine, Central Arkansas VA Health Care System, Little Rock, Arkansas, USA.
Abstract
BACKGROUND: Data on outcomes of ST-elevation myocardial infarction (STEMI) in patients with cancer are scarce. We investigated the nationwide trends in admissions for STEMI, utilization of percutaneous coronary intervention (PCI), and in-hospital outcomes in patients with the three most common cancer diagnoses (lung, breast, and colon) compared to patients without cancer. METHODS: We conducted an administrative database study using the Nationwide Inpatient Sample (NIS). All in-patient hospitalizations for STEMI from 2001 to 2011 were identified. Patients with concomitant diagnosis of lung, breast or colon cancer were identified using appropriate International classification of diagnosis (ICD 9-CM) codes. Primary outcome was utilization of PCI and in-hospital mortality in patients with cancer compared to those without cancer. RESULTS: Utilization of PCI was 30.8% (1,191/3,871), 20.2% (4,541/22,480) and 17.3% (1,716/9,944) in patients with breast, lung and colon cancer, respectively. Among patients without any of these cancers, use of PCI was 49.6%. In-hospital mortality was highest in patients with lung cancer (57.1%) and lowest in patients without cancer (25.7%). CONCLUSIONS: Patients with cancer have significantly worse in-hospital mortality compared to those without cancer, partly due to a relatively lower rate of PCI utilization in cancer patients with STEMI.
BACKGROUND: Data on outcomes of ST-elevation myocardial infarction (STEMI) in patients with cancer are scarce. We investigated the nationwide trends in admissions for STEMI, utilization of percutaneous coronary intervention (PCI), and in-hospital outcomes in patients with the three most common cancer diagnoses (lung, breast, and colon) compared to patients without cancer. METHODS: We conducted an administrative database study using the Nationwide Inpatient Sample (NIS). All in-patient hospitalizations for STEMI from 2001 to 2011 were identified. Patients with concomitant diagnosis of lung, breast or colon cancer were identified using appropriate International classification of diagnosis (ICD 9-CM) codes. Primary outcome was utilization of PCI and in-hospital mortality in patients with cancer compared to those without cancer. RESULTS: Utilization of PCI was 30.8% (1,191/3,871), 20.2% (4,541/22,480) and 17.3% (1,716/9,944) in patients with breast, lung and colon cancer, respectively. Among patients without any of these cancers, use of PCI was 49.6%. In-hospital mortality was highest in patients with lung cancer (57.1%) and lowest in patients without cancer (25.7%). CONCLUSIONS: Patients with cancer have significantly worse in-hospital mortality compared to those without cancer, partly due to a relatively lower rate of PCI utilization in cancer patients with STEMI.
Authors: Cezar A Iliescu; Cindy L Grines; Joerg Herrmann; Eric H Yang; Mehmet Cilingiroglu; Konstantinos Charitakis; Abdul Hakeem; Konstantinos P Toutouzas; Massoud A Leesar; Konstantinos Marmagkiolis Journal: Catheter Cardiovasc Interv Date: 2016-01-12 Impact factor: 2.692
Authors: Ana Barac; Gillian Murtagh; Joseph R Carver; Ming Hui Chen; Andrew M Freeman; Joerg Herrmann; Cezar Iliescu; Bonnie Ky; Erica L Mayer; Tochi M Okwuosa; Juan Carlos Plana; Thomas D Ryan; Anne K Rzeszut; Pamela S Douglas Journal: J Am Coll Cardiol Date: 2015-06-30 Impact factor: 24.094
Authors: Matthijs A Velders; Helèn Boden; Sjoerd H Hofma; Susanne Osanto; Bas L van der Hoeven; Anton A C M Heestermans; Suzanne C Cannegieter; J Wouter Jukema; Victor A W M Umans; Martin J Schalij; Adrianus J van Boven Journal: Am J Cardiol Date: 2013-09-21 Impact factor: 2.778
Authors: Mohammed Osman; Mina M Benjamin; Sudarshan Balla; Babikir Kheiri; Christopher Bianco; Partho P Sengupta; Ramesh Daggubati; Midhun Malla; Stephen V Liu; Mamas Mamas; Brijesh Patel Journal: Cardiovasc Revasc Med Date: 2021-04-16
Authors: Stefan A Lange; Jannik Feld; Leonie Kühnemund; Jeanette Köppe; Lena Makowski; Christiane M Engelbertz; Joachim Gerß; Patrik Dröge; Thomas Ruhnke; Christian Günster; Eva Freisinger; Holger Reinecke Journal: Cancers (Basel) Date: 2021-12-09 Impact factor: 6.639