Literature DB >> 29296859

Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia.

Karine Darbinyan1, Aditi Shastri2, Anjali Budhathoki2, Daniel Helbig3, Rose Snyder3, Kith Pradhan4, Junaid Saleh-Esa2, Noah S Kornblum2, Adam F Binder2, Swati Goel2, Murali Janakiram2, Olga Derman2, Kira Gritsman2, Ulrich Steidl2, Ira Braunschweig2, Amit Verma2, Ioannis Mantzaris2.   

Abstract

SEER data and a Bronx validation cohort demonstrate that Hispanics present with AML at younger age but have shorter survival than whites.Increased frequency of high-risk mutations in Hispanics provides a potential biologic explanation for poorer outcomes in Hispanics.

Entities:  

Year:  2017        PMID: 29296859      PMCID: PMC5737118          DOI: 10.1182/bloodadvances.2017007013

Source DB:  PubMed          Journal:  Blood Adv        ISSN: 2473-9529


  16 in total

1.  Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials.

Authors:  David Grimwade; Robert K Hills; Anthony V Moorman; Helen Walker; Stephen Chatters; Anthony H Goldstone; Keith Wheatley; Christine J Harrison; Alan K Burnett
Journal:  Blood       Date:  2010-04-12       Impact factor: 22.113

2.  Effects of poverty and race on outcomes in acute myeloid leukemia.

Authors:  Margaret M Byrne; L Jill Halman; Leonidas G Koniaris; Peter A Cassileth; Joseph D Rosenblatt; Michael C Cheung
Journal:  Am J Clin Oncol       Date:  2011-06       Impact factor: 2.339

3.  Acute leukemia incidence and patient survival among children and adults in the United States, 2001-2007.

Authors:  Graça M Dores; Susan S Devesa; Rochelle E Curtis; Martha S Linet; Lindsay M Morton
Journal:  Blood       Date:  2011-11-15       Impact factor: 22.113

4.  Cancer survival among US whites and minorities: a SEER (Surveillance, Epidemiology, and End Results) Program population-based study.

Authors:  Limin X Clegg; Frederick P Li; Benjamin F Hankey; Kenneth Chu; Brenda K Edwards
Journal:  Arch Intern Med       Date:  2002-09-23

5.  Differences in prognostic factors and outcomes in African Americans and whites with acute myeloid leukemia.

Authors:  Mikkael A Sekeres; Bercedis Peterson; Richard K Dodge; Robert J Mayer; Joseph O Moore; Edward J Lee; Jonathan Kolitz; Maria R Baer; Charles A Schiffer; Andrew J Carroll; James W Vardiman; Frederick R Davey; Clara D Bloomfield; Richard A Larson; Richard M Stone
Journal:  Blood       Date:  2004-02-19       Impact factor: 22.113

6.  Age and genetics: how do prognostic factors at diagnosis explain disparities in acute myeloid leukemia?

Authors:  Manali I Patel; Yifei Ma; Beverly S Mitchell; Kim F Rhoads
Journal:  Am J Clin Oncol       Date:  2015-04       Impact factor: 2.339

7.  Cancer statistics, 2006.

Authors:  Ahmedin Jemal; Rebecca Siegel; Elizabeth Ward; Taylor Murray; Jiaquan Xu; Carol Smigal; Michael J Thun
Journal:  CA Cancer J Clin       Date:  2006 Mar-Apr       Impact factor: 508.702

8.  The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties.

Authors:  D Grimwade; H Walker; F Oliver; K Wheatley; C Harrison; G Harrison; J Rees; I Hann; R Stevens; A Burnett; A Goldstone
Journal:  Blood       Date:  1998-10-01       Impact factor: 22.113

Review 9.  Cancer disparities by race/ethnicity and socioeconomic status.

Authors:  Elizabeth Ward; Ahmedin Jemal; Vilma Cokkinides; Gopal K Singh; Cheryll Cardinez; Asma Ghafoor; Michael Thun
Journal:  CA Cancer J Clin       Date:  2004 Mar-Apr       Impact factor: 508.702

10.  Racial disparities in the survival of American children, adolescents, and young adults with acute lymphoblastic leukemia, acute myelogenous leukemia, and Hodgkin lymphoma.

Authors:  Justine M Kahn; Theresa H M Keegan; Li Tao; Renata Abrahão; Archie Bleyer; Aaron D Viny
Journal:  Cancer       Date:  2016-06-10       Impact factor: 6.860

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  1 in total

1.  Blood cancer health disparities in the United States Hispanic population.

Authors:  Alfonso E Bencomo-Alvarez; Andres J Rubio; Mayra A Gonzalez; Anna M Eiring
Journal:  Cold Spring Harb Mol Case Stud       Date:  2021-04-08
  1 in total

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