| Literature DB >> 29296495 |
Van Gia Truong1,2, Suhyun Park3,2, Van Nam Tran1, Hyun Wook Kang4,5.
Abstract
A uniformly diffusing applicator can be advantageous for laser treatment of tubular tissue. The current study investigated various conical angles for diffuser tips as a critical factor for achieving radially uniform light emission. A customized goniometer was employed to characterize the spatial uniformity of the light propagation. An ex vivo model was developed to quantitatively compare the temperature development and irreversible tissue coagulation. The 10-mm diffuser tip with angle at 25° achieved a uniform longitudinal intensity profile (i.e., 0.90 ± 0.07) as well as a consistent thermal denaturation on the tissue. The proposed conical angle can be instrumental in determining the uniformity of light distribution for the photothermal treatment of tubular tissue.Keywords: (120.6810) Thermal effects; (140.3390) Laser materials processing; (170.1610) Clinical applications; (170.3660) Light propagation in tissues; (230.1980) Diffusers
Year: 2017 PMID: 29296495 PMCID: PMC5745110 DOI: 10.1364/BOE.8.005663
Source DB: PubMed Journal: Biomed Opt Express ISSN: 2156-7085 Impact factor: 3.732