Literature DB >> 15945145

Design and performance of thin cylindrical diffusers created in Ge-doped multimode optical fibers.

Leonid Vesselov1, William Whittington, Lothar Lilge.   

Abstract

Cylindrical fiber diffusers have become common tools for various medical therapies. However, their large outer diameters and short lengths restrict their clinical application in some newly developed light therapies. Here, a 250-microm outer-diameter diffuser with an active length that exceeds 5 cm is presented. Diffusers are created in photosensitive optical fibers with outer cladding diameters of 140 microm by use of a structured beam from an excimer laser. Predetermined emission profiles can be achieved. Photometric characteristics, including longitudinal, polar, and azimuthal emission diagrams, were determined by use of a goniometer to assess the light-emission performance of the diffuser. Longitudinal isotropy of better than +/- 10% was achieved. Polar and azimuthal emissions were within +/- 15% of those of an ideal linear Lambertian emitter. Polar uniformity could be improved by an insignificant increase in the outer diameter by use of a diffusing recoating compound. The residual leakage of light at the distal end of the diffuser can be as little as 1%. Other physical parameters tested include minimal bending radius after recoating (< 5 mm) and maximum power handling (> 1.0W cm(-1)). All materials employed were biocompatible.

Year:  2005        PMID: 15945145     DOI: 10.1364/ao.44.002754

Source DB:  PubMed          Journal:  Appl Opt        ISSN: 1559-128X            Impact factor:   1.980


  9 in total

1.  Fiberoptic microneedles: novel optical diffusers for interstitial delivery of therapeutic light.

Authors:  Mehmet A Kosoglu; Robert L Hood; John H Rossmeisl; David C Grant; Yong Xu; John L Robertson; Marissa Nichole Rylander; Christopher G Rylander
Journal:  Lasers Surg Med       Date:  2011-11       Impact factor: 4.025

2.  Treatment planning using tailored and standard cylindrical light diffusers for photodynamic therapy of the prostate.

Authors:  Augusto Rendon; J Christopher Beck; Lothar Lilge
Journal:  Phys Med Biol       Date:  2008-02-05       Impact factor: 3.609

Review 3.  The role of photodynamic therapy (PDT) physics.

Authors:  Timothy C Zhu; Jarod C Finlay
Journal:  Med Phys       Date:  2008-07       Impact factor: 4.071

4.  Fabrication and characterization of cylindrical light diffusers comprised of shape memory polymer.

Authors:  Ward Small; Patrick R Buckley; Thomas S Wilson; Jeffrey M Loge; Kristen D Maitland; Duncan J Maitland
Journal:  J Biomed Opt       Date:  2008 Mar-Apr       Impact factor: 3.170

5.  Spatial effect of conical angle on optical-thermal distribution for circumferential photocoagulation.

Authors:  Van Gia Truong; Suhyun Park; Van Nam Tran; Hyun Wook Kang
Journal:  Biomed Opt Express       Date:  2017-11-16       Impact factor: 3.732

6.  Definitive surgery and intraoperative photodynamic therapy: a prospective study of local control and survival for patients with pleural dissemination of non-small cell lung cancer.

Authors:  Charles B Simone; Keith A Cengel
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2014-03-18

7.  Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-Scattering Fiber Diffuser.

Authors:  Mucong Li; Tri Vu; Georgy Sankin; Brenton Winship; Kohldon Boydston; Russell Terry; Pei Zhong; Junjie Yao
Journal:  IEEE Trans Med Imaging       Date:  2020-12-29       Impact factor: 10.048

8.  Fiber photo-catheters for laser treatment of atrial fibrillation.

Authors:  Igor Peshko; Vladimir Rubtsov; Leonid Vesselov; Gennady Sigal; Hillel Laks
Journal:  Opt Lasers Eng       Date:  2007-04-01       Impact factor: 4.836

Review 9.  Sound Out the Deep Colors: Photoacoustic Molecular Imaging at New Depths.

Authors:  Mucong Li; Nikhila Nyayapathi; Hailey I Kilian; Jun Xia; Jonathan F Lovell; Junjie Yao
Journal:  Mol Imaging       Date:  2020 Jan-Dec       Impact factor: 3.250

  9 in total

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