Literature DB >> 29292603

OPTN/SRTR 2016 Annual Data Report: Liver.

W R Kim1,2, J R Lake1,3, J M Smith1,4, D P Schladt1, M A Skeans1, A M Harper5,6, J L Wainright5,6, J J Snyder1,7, A K Israni1,7,8, B L Kasiske1,8.   

Abstract

Data on adult liver transplants performed in the US in 2016 are no-table for (1) the largest total number of transplants performed (7841); (2) the shortest median waiting time in recent history (11.3 months); (3) continued reduction in waitlist registrations and transplants for hepatitis C-related indications; (4) increasing numbers of patients whose clinical profiles are consistent with non-alcoholic fatty liver disease; and (5) equilibration of transplant rates in patients with and without hepatocellular carcinoma. Despite the increase in the number of available organs, waitlist mortality remained an important concern. Graft survival rates continued to improve. In 2016, 723 new active candidates were added to the pediatric liver transplant waiting list, down from a peak of 826 in 2005. The number of prevalent candidates (on the list on December 31 of the given year) was stable, 408 active and 169 inactive. The number of pediatric living donor liver transplants decreased from a peak of 79 in 2015 to 62 in 2016, with most from donors closely related to the recipients. Graft survival continued to improve over the past decade among recipients of deceased donor and living donor livers. .

Entities:  

Keywords:  Liver transplant; allocation; distribution; waiting list

Mesh:

Year:  2018        PMID: 29292603     DOI: 10.1111/ajt.14559

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  110 in total

Review 1.  Estimating Prevalence of Hepatitis C Virus Infection in the United States, 2013-2016.

Authors:  Megan G Hofmeister; Elizabeth M Rosenthal; Laurie K Barker; Eli S Rosenberg; Meredith A Barranco; Eric W Hall; Brian R Edlin; Jonathan Mermin; John W Ward; A Blythe Ryerson
Journal:  Hepatology       Date:  2018-11-06       Impact factor: 17.425

2.  Declining predictive performance of the MELD: Cause for concern or reflection of changes in clinical practice?

Authors:  Nadim Mahmud; David S Goldberg
Journal:  Am J Transplant       Date:  2019-10-23       Impact factor: 8.086

Review 3.  Use of Hepatitis C-Positive Liver Grafts in Hepatitis C-Negative Recipients.

Authors:  Akshay Shetty; Adam Buch; Sammy Saab
Journal:  Dig Dis Sci       Date:  2018-12-17       Impact factor: 3.199

4.  Geographic disparities in liver supply/demand ratio within fixed-distance and fixed-population circles.

Authors:  Christine E Haugen; Tanveen Ishaque; Abel Sapirstein; Alexander Cauneac; Dorry L Segev; Sommer Gentry
Journal:  Am J Transplant       Date:  2019-03-18       Impact factor: 8.086

Review 5.  Bioengineering approaches to organ preservation ex vivo.

Authors:  Meghan Pinezich; Gordana Vunjak-Novakovic
Journal:  Exp Biol Med (Maywood)       Date:  2019-03-19

6.  CCR4 expression on host T cells is a driver for alloreactive responses and lung rejection.

Authors:  Vyacheslav Palchevskiy; Ying Ying Xue; Rita Kern; Stephen S Weigt; Aric L Gregson; Sophie X Song; Michael C Fishbein; Cory M Hogaboam; David M Sayah; Joseph P Lynch; Michael P Keane; David G Brooks; John A Belperio
Journal:  JCI Insight       Date:  2019-05-14

7.  Early liver transplant for severe alcoholic hepatitis: establishing a new frontier by ignoring the rule?

Authors:  Julie Zhu; Trana Hussaini; Eric M Yoshida
Journal:  Ann Transl Med       Date:  2018-10

Review 8.  Evolving swaps in transplantation: global exchange, vouchers, liver, and trans-organ paired exchange.

Authors:  Alexis L Lo; Elizabeth M Sonnenberg; Peter L Abt
Journal:  Curr Opin Organ Transplant       Date:  2019-04       Impact factor: 2.640

9.  Impact of the Pediatric End-Stage Liver Disease (PELD) growth failure thresholds on mortality among pediatric liver transplant candidates.

Authors:  Sonja M Swenson; John P Roberts; Sue Rhee; Emily R Perito
Journal:  Am J Transplant       Date:  2019-09-03       Impact factor: 8.086

10.  Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation.

Authors:  Jin Ge; Evelyn K Hsu; John Bucuvalas; Jennifer C Lai
Journal:  Hepatology       Date:  2019-02-08       Impact factor: 17.425

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