| Literature DB >> 29287838 |
Nadezhda Glezeva1, Master Chisale2, Kenneth McDonald1, Mark Ledwidge1, Joe Gallagher1, Chris J Watson3.
Abstract
Type 2 diabetes mellitus is no longer a disease of high income countries but a global health pandemic. With the continued and rapid increase in its prevalence worldwide it is forecasted that diabetes will be a leading cause of morbidity and mortality. A major concern stems from its role in development and progression of cardiovascular disease, including cardiac dysfunction and heart failure. Within low- and middle-income areas such as Sub-Saharan Africa the burden of diabetes is already significant driven by many factors, including, socioeconomic (urbanisation), nutritional (high-calorie "western-diet", obesity) and lifestyle (physical inactivity) changes. Insufficient economic and community resources, poor health care system development and chronic disease management, poor education, and a lack of preventative and diagnostic measures further aggravate the severity of the diabetes problem. This review outlines the burden of type 2 diabetes mellitus in Sub-Saharan Africa and highlights the need for improved community health care and regulations to reduce its epidemiological spread and devastating impact on health.Entities:
Keywords: Cardiovascular disease; Diabetes clinical trials; Diabetic cardiomyopathy; Low-income countries; Sub-Saharan Africa; Type 2 diabetes mellitus
Mesh:
Year: 2017 PMID: 29287838 DOI: 10.1016/j.diabres.2017.12.019
Source DB: PubMed Journal: Diabetes Res Clin Pract ISSN: 0168-8227 Impact factor: 5.602