Literature DB >> 29284126

Metabolic Models of Protein Allocation Call for the Kinetome.

Avlant Nilsson1, Jens Nielsen2, Bernhard O Palsson3.   

Abstract

The flux of metabolites in the living cell depend on enzyme activities. Recently, many metabolic phenotypes have been explained by computer models that incorporate enzyme activity data. To move further, the scientific community needs to measure the kinetics of all enzymes in a systematic way.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 29284126     DOI： 10.1016/j.cels.2017.11.013

Source DB:  PubMed          Journal:  Cell Syst        ISSN： 2405-4712            Impact factor:   10.304


  17 in total

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Review 2.  Integrating Systems and Synthetic Biology to Understand and Engineer Microbiomes.

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Journal:  mSystems       Date:  2022-04-06       Impact factor: 7.324

4.  Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models.

Authors:  David Heckmann; Colton J Lloyd; Nathan Mih; Yuanchi Ha; Daniel C Zielinski; Zachary B Haiman; Abdelmoneim Amer Desouki; Martin J Lercher; Bernhard O Palsson
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5.  Machine Learning Predicts the Yeast Metabolome from the Quantitative Proteome of Kinase Knockouts.

Authors:  Aleksej Zelezniak; Jakob Vowinckel; Floriana Capuano; Christoph B Messner; Vadim Demichev; Nicole Polowsky; Michael Mülleder; Stephan Kamrad; Bernd Klaus; Markus A Keller; Markus Ralser
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Authors:  Colton J Lloyd; Zachary A King; Troy E Sandberg; Ying Hefner; Connor A Olson; Patrick V Phaneuf; Edward J O'Brien; Jon G Sanders; Rodolfo A Salido; Karenina Sanders; Caitriona Brennan; Gregory Humphrey; Rob Knight; Adam M Feist
Journal:  PLoS Comput Biol       Date:  2019-03-01       Impact factor: 4.475

7.  Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism.

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Review 8.  Constraint-based modeling in microbial food biotechnology.

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Journal:  Biochem Soc Trans       Date:  2018-03-27       Impact factor: 5.407

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Journal:  Sci Rep       Date:  2020-03-09       Impact factor: 4.379

10.  An analytical theory of balanced cellular growth.

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Journal:  Nat Commun       Date:  2020-03-06       Impact factor: 14.919
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