| Literature DB >> 29279339 |
Josef Stehlik1, Jon Kobashigawa2, Sharon A Hunt3, Hermann Reichenspurner4, James K Kirklin5.
Abstract
Heart transplantation has become a standard therapy option for advanced heart failure. The translation of heart transplantation from innovative experiments to long-term clinical success has married prescient insights with discipline and organization in the domains of surgical techniques, organ preservation, immunosuppression, organ donation and transplantation logistics, infection control, and long-term graft surveillance. This review explores the key milestones of the past 50 years of heart transplantation and discusses current challenges and promising innovations on the clinical horizon.Entities:
Keywords: heart transplantation; immunosuppression; survival
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Year: 2018 PMID: 29279339 DOI: 10.1161/CIRCULATIONAHA.117.029753
Source DB: PubMed Journal: Circulation ISSN: 0009-7322 Impact factor: 29.690