| Literature DB >> 29278921 |
Arshad Mehmood1,2,3, Lei Zhao1,2, Chengtao Wang1,2, Muhammad Nadeem3, Ali Raza1,2, Nawazish Ali1,2, Amjad Abbas Shah3.
Abstract
Hyperuricemia, a condition due to high serum uric acid level and is notorious to health. It is considered to be a potent risk factor for gout and dramatically associated in the development of many chronic diseases such as malignant tumor, cardiovascular disorders and renal failure. Modern innovative medicinal and therapeutic interventions are underlying these days to combat hyperuricemia. Previously reported studies revealed the significant impact of dietary polyphenols (e.g. anthocyanins, phenolic acids, flavonoids etc.) against hyperurecemia disorder. Dietary plant polyphenols, unlike anti- hyperuricemic agents, are not reported to have any side effects in curing hyperuricemia. The current comprehensive review figure outs the use of dietary polyphenols as a natural remedy for the management of hyperuricemia. The sources, affiliated pathways, mode of actions and factors affecting their efficiency to prevent hyperuricemia are deeply discussed in this article. Additionally, limitations and suggestions regarding previously reported studies are also highlighted.Entities:
Keywords: Hyperuricemia; gout; mode of action; polyphenols; therapeutic interventions; uric acid; xanthine oxidase
Mesh：
Substances：
Year: 2017 PMID： 29278921 DOI： 10.1080/10408398.2017.1412939
Source DB: PubMed Journal: Crit Rev Food Sci Nutr ISSN： 1040-8398 Impact factor: 11.176