Literature DB >> 29278650

Synthesis of [15 N]-cholamine bromide hydrobromide.

Judy Szeto1, Remy Lemoine1, Rosary Nguyen1, Lori L Olson1, Mary J Tanga1.   

Abstract

[15 N]-Cholamine is an isotope tag for metabolomics research, because it possesses 2 important properties: an NMR active isotope and a permanent charge for MS sensitivity. Here, we present a scalable synthesis of n class="Chemical">[15 N]-cholamine.
Copyright © 2017 John Wiley & Sons, Ltd.

Entities:  

Keywords:  [15N]-cholamine bromide hydrobromide; carboxylic acid metabolites; chemo-selective tag; smart isotope tag

Mesh：

Substances：

Year:  2018        PMID： 29278650      PMCID： PMC5912969          DOI： 10.1002/jlcr.3598

Source DB:  PubMed          Journal:  J Labelled Comp Radiopharm        ISSN： 0362-4803            Impact factor:   1.921


  2 in total

1.  15N-cholamine--a smart isotope tag for combining NMR- and MS-based metabolite profiling.

Authors:  Fariba Tayyari; G A Nagana Gowda; Haiwei Gu; Daniel Raftery
Journal:  Anal Chem       Date:  2013-08-26       Impact factor: 6.986

2.  HMDB 3.0--The Human Metabolome Database in 2013.

Authors:  David S Wishart; Timothy Jewison; An Chi Guo; Michael Wilson; Craig Knox; Yifeng Liu; Yannick Djoumbou; Rupasri Mandal; Farid Aziat; Edison Dong; Souhaila Bouatra; Igor Sinelnikov; David Arndt; Jianguo Xia; Philip Liu; Faizath Yallou; Trent Bjorndahl; Rolando Perez-Pineiro; Roman Eisner; Felicity Allen; Vanessa Neveu; Russ Greiner; Augustin Scalbert
Journal:  Nucleic Acids Res       Date:  2012-11-17       Impact factor: 16.971
  2 in total
  1 in total

1.  NMR Analysis of Carboxylate Isotopomers of 13C-Metabolites by Chemoselective Derivatization with 15N-Cholamine.

Authors:  Sara Vicente-Muñoz; Penghui Lin; Teresa W-M Fan; Andrew N Lane
Journal:  Anal Chem       Date:  2021-04-21       Impact factor: 8.008
  1 in total

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