Literature DB >> 29275393

Unusual case of anxiety: trichloroethylene neurotoxicity.

Joshua Au Yeung1.   

Abstract

I present an uncommon case of recurrent, intractable anxiety that was presented acutely and slowly evolved into a chronic debilitating condition. A young previously fit and healthy 24-year-old patient presents with somewhat atypical symptoms of anxiety. Full medical work-up including examination, blood, ECG electrocardiogram, electroencephalogram and CT of the head was unremarkable. When the history was explored in detail, it was revealed he worked in the navy and was exposed to a neurotoxic solvent, trichloroethylene. This case highlights the importance of eliciting a detailed occupational history, particularly paying attention to patient demographics such as occupation and presenting symptoms that do not readily fit into diagnostic criteria. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  anxiety disorders (including ocd and ptsd); drugs: psychiatry; neurological injury; neurology (drugs and medicines); psychiatry

Mesh:

Substances:

Year:  2017        PMID: 29275393      PMCID: PMC5780591          DOI: 10.1136/bcr-2017-223074

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

Review 1.  Anxiety disorders.

Authors:  Jian-Ping Chen; Leonard Reich; Henry Chung
Journal:  West J Med       Date:  2002-09

2.  Traumatic brain injury and trichloroethylene exposure interact and produce functional, histological, and mitochondrial deficits.

Authors:  Andrew Sauerbeck; Randy Hunter; Guoying Bing; Patrick G Sullivan
Journal:  Exp Neurol       Date:  2011-12-20       Impact factor: 5.330

3.  Increased incidence of anxiety and depressive disorders in persons with organic solvent exposure.

Authors:  L A Morrow; C Gibson; G R Bagovich; L Stein; R Condray; A Scott
Journal:  Psychosom Med       Date:  2000 Nov-Dec       Impact factor: 4.312

4.  Long-term health effects of early life exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study.

Authors:  Ann Aschengrau; Michael R Winter; Veronica M Vieira; Thomas F Webster; Patricia A Janulewicz; Lisa G Gallagher; Janice Weinberg; David M Ozonoff
Journal:  Environ Health       Date:  2015-04-12       Impact factor: 5.984

  4 in total

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