OBJECTIVE: The purpose of this study was to determine whether the prevalence of current and past DSM-IV axis I psychiatric disorders is higher among persons with a history of exposure to organic solvents than among a demographically similar group of nonexposed control subjects. METHODS: Thirty-eight solvent-exposed subjects and 39 nonexposed healthy control subjects were evaluated for axis I disorder with the Structured Clinical Interview for DSM-IV. RESULTS: A significantly higher number of solvent-exposed subjects (71%) met criteria for current DSM-IV axis I disorder in comparison with control subjects (10%). The most prevalent diagnosis in exposed subjects was within the anxiety and mood clusters, with a high percentage (36%) of exposed subjects meeting criteria for a dual diagnosis of mood and anxiety disorder. There were no differences between the groups in past psychiatric disorders or current or past substance abuse or dependence. CONCLUSIONS: The rates of past psychiatric disorders among solvent-exposed subjects are similar to those among normal control subjects, but the prevalence of current DSM-IV axis I psychiatric disorders is significantly higher among exposed subjects than among control subjects.
OBJECTIVE: The purpose of this study was to determine whether the prevalence of current and past DSM-IV axis I psychiatric disorders is higher among persons with a history of exposure to organic solvents than among a demographically similar group of nonexposed control subjects. METHODS: Thirty-eight solvent-exposed subjects and 39 nonexposed healthy control subjects were evaluated for axis I disorder with the Structured Clinical Interview for DSM-IV. RESULTS: A significantly higher number of solvent-exposed subjects (71%) met criteria for current DSM-IV axis I disorder in comparison with control subjects (10%). The most prevalent diagnosis in exposed subjects was within the anxiety and mood clusters, with a high percentage (36%) of exposed subjects meeting criteria for a dual diagnosis of mood and anxiety disorder. There were no differences between the groups in past psychiatric disorders or current or past substance abuse or dependence. CONCLUSIONS: The rates of past psychiatric disorders among solvent-exposed subjects are similar to those among normal control subjects, but the prevalence of current DSM-IV axis I psychiatric disorders is significantly higher among exposed subjects than among control subjects.
Authors: Patricia A Janulewicz; Roberta F White; Brett M Martin; Michael R Winter; Janice M Weinberg; Veronica Vieira; Ann Aschengrau Journal: Neurotoxicol Teratol Date: 2012-04-12 Impact factor: 3.763
Authors: Patricia A Janulewicz; Roberta F White; Michael R Winter; Janice M Weinberg; Lisa E Gallagher; Veronica Vieira; Thomas F Webster; Ann Aschengrau Journal: Neurotoxicol Teratol Date: 2008-02-11 Impact factor: 3.763
Authors: Patricia A Janulewicz; Ronald J Killiany; Roberta F White; Brett M Martin; Michael R Winter; Janice M Weinberg; Ann Aschengrau Journal: Neurotoxicol Teratol Date: 2013-04-06 Impact factor: 3.763
Authors: Ann Aschengrau; Janice M Weinberg; Patricia A Janulewicz; Megan E Romano; Lisa G Gallagher; Michael R Winter; Brett R Martin; Veronica M Vieira; Thomas F Webster; Roberta F White; David M Ozonoff Journal: Environ Health Date: 2011-12-02 Impact factor: 5.984