Adam Rzechonek1, Piotr Błasiak2, Grzegorz Pniewski3, Piotr Cierpikowski2, Monika Mościbrodzka4, Maciej Ornat5, Jędrzej Grzegrzółka5, Anna Brzecka6. 1. Department and Clinic of Thoracic Surgery, Wroclaw Medical University, Wroclaw, Poland adam.rzechonek@gmail.com. 2. Department and Clinic of Thoracic Surgery, Wroclaw Medical University, Wroclaw, Poland. 3. Department of Thoracic Surgery, Lower Silesian Centre for Lung Diseases, Wroclaw, Poland. 4. Institute of Economic Sciences, Department of Statistics and Operational Research, University of Wroclaw, Wroclaw, Poland. 5. Department of Histology and Embryology, Wroclaw Medical University, Wroclaw, Poland. 6. Department and Clinic of Pulmonology and Lung Cancer, Wroclaw Medical University, Wroclaw, Poland.
Abstract
BACKGROUND/AIM: The aim of the study was to determine whether increased body mass index (BMI) in patients operated on for lung metastases influences the course of the disease. MATERIALS AND METHODS: The retrospective data of 97 patients previously operated on for different malignancies were analyzed. There were 40 obese patients (BMI >30 kg/m2, mean 33.9±4.5) and 57 non-obese patients (BMI 25.8±2.7 kg/m2, p<0.001). Disease-free interval (DFI), the overall survival (OS) and survival after pulmonary metastasectomy were analyzed. RESULTS: DFI and OS were longer in obese than in non-obese patients (82.1±83.5 months vs. 43.0±44.4, p<0.01 and 110.7±81.3 months vs. 69.9±52.9 p<0.005, respectively). Survival after pulmonary metastasectomy was 27.2±25.6 months and was longer in obese and overweight patients than in normal weight patients (20.2±18.4 months vs. 29.4±26.5, p<0.05). CONCLUSION: Being obese or overweight is a favorable prognostic factor in patients after surgical resection of lung metastases of different malignancies. Copyright
BACKGROUND/AIM: The aim of the study was to determine whether increased body mass index (BMI) in patients operated on for lung metastases influences the course of the disease. MATERIALS AND METHODS: The retrospective data of 97 patients previously operated on for different malignancies were analyzed. There were 40 obesepatients (BMI >30 kg/m2, mean 33.9±4.5) and 57 non-obesepatients (BMI 25.8±2.7 kg/m2, p<0.001). Disease-free interval (DFI), the overall survival (OS) and survival after pulmonary metastasectomy were analyzed. RESULTS: DFI and OS were longer in obese than in non-obesepatients (82.1±83.5 months vs. 43.0±44.4, p<0.01 and 110.7±81.3 months vs. 69.9±52.9 p<0.005, respectively). Survival after pulmonary metastasectomy was 27.2±25.6 months and was longer in obese and overweight patients than in normal weight patients (20.2±18.4 months vs. 29.4±26.5, p<0.05). CONCLUSION: Being obese or overweight is a favorable prognostic factor in patients after surgical resection of lung metastases of different malignancies. Copyright
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