Literature DB >> 2927059

Serum phospholipase A in hematological diseases.

R T Hiefinger1, W G Guder, G E Hoffmann.   

Abstract

Inflammatory cells, e.g., neutrophils, monocytes, and macrophages are presumed to be a source of circulating phospholipase A in nonpancreatic diseases. Therefore, we investigated in a preliminary study whether serum phospholipase A activity is related to leukocyte counts in 43 patients with hematological diseases. Serum PLA activity was significantly increased in patients with Hodgkin's disease, acute monocytic leukemia, myelofibrosis with myeloid metaplasia, and polycythemia vera when compared with patients with chronic myelogenous leukemia, chronic lymphocytic leukemia, and acute myelogenous leukemia, but did not correlate with total leukocyte counts.

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Year:  1989        PMID: 2927059     DOI: 10.1007/BF01711358

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  10 in total

1.  Photometric determination of phospholipase A.

Authors:  G E Hoffmann; D Schmidt; B Bastian; W G Guder
Journal:  J Clin Chem Clin Biochem       Date:  1986-11

2.  Phospholipase A in acute lung injury after trauma and sepsis: its relation to the inflammatory mediators PMN-elastase, C3a, and neopterin.

Authors:  W Kellermann; R Frentzel-Beyme; M Welte; M Jochum
Journal:  Klin Wochenschr       Date:  1989-02-01

3.  Phospholipase A activity associated with membranes of human polymorphonuclear leucocytes.

Authors:  R Franson; J Weiss; L Martin; J K Spitznagel; P Elsbach
Journal:  Biochem J       Date:  1977-12-01       Impact factor: 3.857

4.  Phospholipase A2 activity in T-lymphocytes.

Authors:  M Goppelt-Struebe; U Kyas; K Resch
Journal:  FEBS Lett       Date:  1986-06-23       Impact factor: 4.124

Review 5.  Role of secretory phospholipases A2 in the pathobiology of disease.

Authors:  P Vadas; W Pruzanski
Journal:  Lab Invest       Date:  1986-10       Impact factor: 5.662

6.  Rapid determination of phospholipase A in human serum and plasma.

Authors:  G E Hoffmann; V Kozumplik; R Beck; W Kellermann
Journal:  Clin Chem       Date:  1987-07       Impact factor: 8.327

7.  Phospholipase and prophospholipase activities in bronchoalveolar lavage fluid in severe acute pulmonary disease with or without ARDS.

Authors:  G Offenstadt; P Pinta; J Masliah; L G Alcindor; P Héricord; P Amstutz
Journal:  Intensive Care Med       Date:  1981       Impact factor: 17.440

8.  Elevated plasma phospholipase A2 levels: correlation with the hemodynamic and pulmonary changes in gram-negative septic shock.

Authors:  P Vadas
Journal:  J Lab Clin Med       Date:  1984-12

9.  Serum activities of phospholipase A in acute posttraumatic pulmonary insufficiency.

Authors:  R Koeniger; G E Hoffmann; T O Schmid
Journal:  Klin Wochenschr       Date:  1989-02-01

10.  Activity of phospholipase A compared in serum of patients with pancreatic and nonpancreatic diseases.

Authors:  D Schmidt; G E Hoffmann
Journal:  Clin Chem       Date:  1987-04       Impact factor: 8.327

  10 in total
  2 in total

1.  Elevation of serum phospholipase A2 in patients at an intensive care unit.

Authors:  M Kitagawa; T Hayakawa; T Kondo; T Shibata; Y Sakai; H Sobajima; H Ishiguro; M Tanikawa; Y Nakae; S Kameya
Journal:  Int J Pancreatol       Date:  1991 Nov-Dec

Review 2.  Serum phospholipase--regulatory and pathophysiological aspects.

Authors:  G E Hoffmann; W G Guder
Journal:  Klin Wochenschr       Date:  1989-02-01
  2 in total

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