Elisabet Mauri-Obradors1, Alexandra Merlos2, Albert Estrugo-Devesa1, Enric Jané-Salas1,3, José López-López1,3, Miguel Viñas2. 1. Department of Dentistry, Dental School, University of Barcelona, Barcelona, Spain. 2. Department of Pathology and Experimental Therapeutics, Medical School, IDIBELL-University of Barcelona, Barcelona, Spain. 3. Oral Medicine Unit, Department of Dentistry, Faculty of Medicine and Health Sciences (Dental School) and Dental Hospital Barcelona University (University of Barcelona) and Health and Masticatory System Group (Bellvitge Biomedical Research, Institute) IDIBELL, Barcelona, Spain.
Abstract
BACKGROUND: Periodontitis and diabetes are highly prevalent conditions whose association has long been recognized. OBJECTIVE: To evaluate the effect of non-surgical periodontal treatment on serum HbA1c (haemoglobinA1c or glycated haemoglobin) levels in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a 6-month, single-masked, randomized clinical trial based on 90 patients (HbA1c: 7.7% (61 mmol/mol) ± 1.13%) who were randomly assigned to either the treatment group (oral hygiene instructions + scaling and root planing using ultrasound and Gracey curettes) or the control group (oral hygiene instructions + supragingival removal of plaque and calculus using ultrasound). Pocket depth, gingival index, and plaque index were assessed at baseline and after 3 and 6 months together with determinations of fasting plasma glucose, HbA1c, and bacterial counts. RESULTS: Treatment significantly improved the periodontal and metabolic parameters (p < .05), whereas in the control group no improvement was observed. These results were consistent with the bacteriological results in most but not all cases. CONCLUSION: Non-surgical periodontal treatment resulted in a better glycaemic status of type 2 diabetes patients and demonstrated the importance of oral health in their general health.
RCT Entities:
BACKGROUND:Periodontitis and diabetes are highly prevalent conditions whose association has long been recognized. OBJECTIVE: To evaluate the effect of non-surgical periodontal treatment on serum HbA1c (haemoglobin A1c or glycated haemoglobin) levels in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a 6-month, single-masked, randomized clinical trial based on 90 patients (HbA1c: 7.7% (61 mmol/mol) ± 1.13%) who were randomly assigned to either the treatment group (oral hygiene instructions + scaling and root planing using ultrasound and Gracey curettes) or the control group (oral hygiene instructions + supragingival removal of plaque and calculus using ultrasound). Pocket depth, gingival index, and plaque index were assessed at baseline and after 3 and 6 months together with determinations of fasting plasma glucose, HbA1c, and bacterial counts. RESULTS: Treatment significantly improved the periodontal and metabolic parameters (p < .05), whereas in the control group no improvement was observed. These results were consistent with the bacteriological results in most but not all cases. CONCLUSION: Non-surgical periodontal treatment resulted in a better glycaemic status of type 2 diabetespatients and demonstrated the importance of oral health in their general health.
Authors: Terry C Simpson; Janet E Clarkson; Helen V Worthington; Laura MacDonald; Jo C Weldon; Ian Needleman; Zipporah Iheozor-Ejiofor; Sarah H Wild; Ambrina Qureshi; Andrew Walker; Veena A Patel; Dwayne Boyers; Joshua Twigg Journal: Cochrane Database Syst Rev Date: 2022-04-14
Authors: Teodora Rodic; Eva Maria Wölfel; Petar Milovanovic; Imke A K Fiedler; Danica Cvetkovic; Katharina Jähn; Michael Amling; Jelena Sopta; Slobodan Nikolic; Vladimir Zivkovic; Björn Busse; Marija Djuric Journal: Clin Oral Investig Date: 2021-03-11 Impact factor: 3.573