Literature DB >> 2925517

Ramoplanin (A-16686), a new glycolipodepsipeptide antibiotic. IV. Complete sequence determination by homonuclear 2D NMR spectroscopy.

J K Kettenring1, R Ciabatti, G Winters, G Tamborini, B Cavalleri.   

Abstract

Homonuclear 2D NMR spectroscopy double quantum filter correlation spectroscopy (DQF-COSY), relayed-COSY, nuclear Overhauser enhancement spectroscopy (NOESY), and DQF-relayed-NOESY) allowed the complete determination of the core depsipeptide of antibiotic ramoplanin (A-16686). In particular, the DQF-relayed-NOESY experiments were essential in assigning the single signals close to the diagonal.

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Year:  1989        PMID: 2925517     DOI: 10.7164/antibiotics.42.268

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  4 in total

Review 1.  Recent advances in the chemistry and biology of naturally occurring antibiotics.

Authors:  K C Nicolaou; Jason S Chen; David J Edmonds; Anthony A Estrada
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

2.  Alanine scan of [L-Dap(2)]ramoplanin A2 aglycon: assessment of the importance of each residue.

Authors:  Joonwoo Nam; Dongwoo Shin; Yosup Rew; Dale L Boger
Journal:  J Am Chem Soc       Date:  2007-06-26       Impact factor: 15.419

3.  Total synthesis and structure of the ramoplanin A1 and A3 aglycons: two minor components of the ramoplanin complex.

Authors:  Dongwoo Shin; Yosup Rew; Dale L Boger
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-02       Impact factor: 11.205

4.  Isolation, structure determination and biological activity of A-16686 factors A' 1, A' 2 and A' 3 glycolipodepsipeptide antibiotics.

Authors:  L Gastaldo; R Ciabatti; F Assi; E Restelli; J K Kettenring; L F Zerilli; G Romanò; M Denaro; B Cavalleri
Journal:  J Ind Microbiol       Date:  1992-11
  4 in total

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