Literature DB >> 29249623

Growth hormone and insulin-like growth factor-I axis in type 1 diabetes.

Bimota Nambam1, Desmond Schatz2.   

Abstract

The precise mechanisms relating type 1 diabetes (T1D) and poor glycemic control to the axis of growth hormone (GH), insulin like growth factor- I (IGF-I), and IGF binding protein-3 (IGFBP-3) remain to be definitively determined. GH resistance with low IGF-I as is frequently seen in patients with T1D is often related to portal hypoinsulization, and lack of upregulation of GH receptors. There are conflicting reports of the effect of a dysregulated GH/IGF-I axis on height in children and adolescents with T1D, as well as on chronic complications. This brief review discusses some of the interactions between the GH/IGF-I axis and T1D pathology, and vice-versa.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Growth hormone; Height; Insulin like growth factor-I; Portal hypoinsulinization; Type 1 diabetes

Mesh：

Substances：

Year:  2017        PMID： 29249623     DOI： 10.1016/j.ghir.2017.12.005

Source DB:  PubMed          Journal:  Growth Horm IGF Res        ISSN： 1096-6374            Impact factor:   2.372


  7 in total

Review 1.  The Interplay Between Pituitary Health and Diabetes Mellitus - The Need for 'Hypophyseo-Vigilance'.

Authors:  Saptarshi Bhattacharya; Sanjay Kalra; Deep Dutta; Deepak Khandelwal; Rajiv Singla
Journal:  Eur Endocrinol       Date:  2019-10-18

2.  Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis.

Authors:  Melanie R Shapiro; Clive H Wasserfall; Sean M McGrail; Amanda L Posgai; Rhonda Bacher; Andrew Muir; Michael J Haller; Desmond A Schatz; Johnna D Wesley; Matthias von Herrath; William A Hagopian; Cate Speake; Mark A Atkinson; Todd M Brusko
Journal:  Diabetes       Date:  2019-12-11       Impact factor: 9.461

3.  Higher HbA1c may reduce axial length elongation in myopic children: a comparison cohort study.

Authors:  Chun-Fu Liu; Shin-Chieh Chen; Fu-Sung Lo; Nan-Kai Wang; Kuan-Jen Chen; Laura Liu; Yen-Po Chen; Eugene Yu-Chuan Kang; Pei-Kang Liu; Ling Yeung; Wei-Chi Wu; Chi-Chun Lai
Journal:  Acta Diabetol       Date:  2021-02-15       Impact factor: 4.087

4.  Childhood Height Growth Rate Association With the Risk of Islet Autoimmunity and Development of Type 1 Diabetes.

Authors:  Zhiguo Li; Riitta Veijola; Eileen Koski; Vibha Anand; Frank Martin; Kathleen Waugh; Heikki Hyöty; Christiane Winkler; Michael B Killian; Markus Lundgren; Kenney Ng; Marlena Maziarz; Jorma Toppari
Journal:  J Clin Endocrinol Metab       Date:  2022-05-17       Impact factor: 6.134

5.  Inhibitor of IGF1 receptor alleviates the inflammation process in the diabetic kidney mouse model without activating SOCS2.

Authors:  Jiayu Li; Rong Dong; Jiali Yu; Sun Yi; Jingjing Da; Fuxun Yu; Yan Zha
Journal:  Drug Des Devel Ther       Date:  2018-09-11       Impact factor: 4.162

6.  Evaluation of Diabetes Effects on the Expression of Leukemia Inhibitory Factor and Vascular Endothelial Growth Factor A Genes and Proteins at the Time of Endometrial Receptivity after Superovulation in Rat Model.

Authors:  Ronak Zarei; Parvaneh Nikpour; Bahman Rashidi; Nahid Eskandari; Roshanak Aboutorabi
Journal:  Adv Biomed Res       Date:  2019-11-27

Review 7.  Insulin-like Growth Factor and its Therapeutic Potential for Diabetes Complications - Mechanisms and Metabolic Links: A Review.

Authors:  Belete Biadgo; Workineh Tamir; Sintayehu Ambachew
Journal:  Rev Diabet Stud       Date:  2020-12-28
  7 in total

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