Literature DB >> 29247255

[Adequate prescription and application of topicals : How to calculate the right volume for the prescription of ointment needed?]

D Homayoon1, P Dahlhoff2, M Augustin2.   

Abstract

BACKGROUND: Uncertainty regarding the suitable amount of prescribed ointment and its application by patients may cause insufficient or uneconomic health care provision. To address this issue, standardized methods and experts' knowledge on the suitable amount and coherent patient's elucidation for application of topicals are needed.
OBJECTIVES: Presented are current data in routine care and scientific evidence on the prescribed amount of topical agents as well as its application by patients in dermatological care.
MATERIALS AND METHODS: A literature review was conducted via PubMed using the keywords as individual and pooled search terms: "local therapy", "topical treatment", "prescription", "amount of ointment needed", "involved area", "BSA", "finger-tip-unit", "Rule of Hand", "calculated dosage" and "rule of nines". We included original studies by manually screening title and abstract according to the relevance of the topic.
RESULTS: The search strategy identified 19 clinical trials. The fingertip unit (FTU) is the most frequently used measurement for accurate application of external agents. Appropriate prescribed amount is calculated by required topical agent per involved surface area.
CONCLUSIONS: There is still a need for clarification to which extent the optimized amount of ointment is prescribed and advice for its application in routine care is given. The FTU combined with the "Rule of Hand" is an adequate measurement for patient's guidance on self-application.

Entities:  

Keywords:  Application requirements; Fingertip unit; Local therapy; Rule of Hand; Self-application

Mesh:

Substances:

Year:  2018        PMID: 29247255     DOI: 10.1007/s00105-017-4088-z

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  19 in total

1.  Topical corticosteroid in foam vehicle offers comparable coverage compared with traditional vehicles.

Authors:  S R Feldman; N Sangha; V Setaluri
Journal:  J Am Acad Dermatol       Date:  2000-06       Impact factor: 11.527

2.  How much of a topical agent should be prescribed for children of different sizes?

Authors:  Andrew A Nelson; Alicia D Miller; Alan B Fleischer; Rajesh Balkrishnan; Steven R Feldman
Journal:  J Dermatolog Treat       Date:  2006       Impact factor: 3.359

3.  Are we giving patients enough information on how to use topical treatments? Analysis of 767 prescriptions in psoriasis.

Authors:  C Pouplard; P-A Gourraud; N Meyer; C B Livideanu; M Lahfa; J Mazereeuw-Hautier; P Le Jeunne; A-L Sabatini; C Paul
Journal:  Br J Dermatol       Date:  2011-10-17       Impact factor: 9.302

4.  "Fingertip unit" in dermatology.

Authors:  A Y Finlay; P H Edwards; K G Harding
Journal:  Lancet       Date:  1989-07-15       Impact factor: 79.321

5.  A practical guide to topical therapy in children.

Authors:  C C Long; C M Mills; A Y Finlay
Journal:  Br J Dermatol       Date:  1998-02       Impact factor: 9.302

Review 6.  The right dose in the right place: an overview of current prescription, instruction and application modalities for topical psoriasis treatments.

Authors:  J Savary; J P Ortonne; S Aractingi
Journal:  J Eur Acad Dermatol Venereol       Date:  2005-11       Impact factor: 6.166

7.  Topical steroid requirement in inflammatory skin conditions.

Authors:  P D Maurice; E M Saihan
Journal:  Br J Clin Pract       Date:  1985 Nov-Dec

8.  A Topical Treatment Optimization Programme (TTOP) improves clinical outcome for calcipotriol/betamethasone gel in psoriasis: results of a 64-week multinational randomized phase IV study in 1790 patients (PSO-TOP).

Authors:  K Reich; I Zschocke; H Bachelez; E M G J de Jong; P Gisondi; L Puig; R B Warren; C Ortland; U Mrowietz
Journal:  Br J Dermatol       Date:  2017-06-06       Impact factor: 9.302

9.  A prospective study of patient adherence to topical treatments: 95% of patients underdose.

Authors:  Andreas Storm; Eva Benfeldt; Stig Ejdrup Andersen; Jørgen Serup
Journal:  J Am Acad Dermatol       Date:  2008-09-24       Impact factor: 11.527

10.  Expert consensus: time for a change in the way we advise our patients to use topical corticosteroids.

Authors:  A Bewley
Journal:  Br J Dermatol       Date:  2008-02-22       Impact factor: 9.302

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