Literature DB >> 16971317

How much of a topical agent should be prescribed for children of different sizes?

Andrew A Nelson1, Alicia D Miller, Alan B Fleischer, Rajesh Balkrishnan, Steven R Feldman.   

Abstract

BACKGROUND: Compared with guidelines for the quantity of topical corticosteroids to apply in adults, standards for the use of topical corticosteroids in children are not well described.
OBJECTIVE: To devise simple-to-use guidelines for topical corticosteroid quantities needed in infants, children, pre-teens, and adults.
METHODS: We determined body surface area (BSA) using mean heights and weights in order to calculate the appropriate quantities of medication to be prescribed.
RESULTS: As a rough estimate, infants require one-fifth of adult doses, children two-fifths of adult doses, and adolescents two-thirds of adult doses. However, the assessment of BSA may vary considerably between clinicians. Patients may also vary in how thickly they apply topical medication.
CONCLUSIONS: A simple guideline for how much topical corticosteroid to prescribe may facilitate the treatment of young children with skin disease.

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Year:  2006        PMID: 16971317     DOI: 10.1080/09546630600894998

Source DB:  PubMed          Journal:  J Dermatolog Treat        ISSN: 0954-6634            Impact factor:   3.359


  4 in total

1.  Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies.

Authors:  Lawrence F Eichenfield; Wynnis L Tom; Timothy G Berger; Alfons Krol; Amy S Paller; Kathryn Schwarzenberger; James N Bergman; Sarah L Chamlin; David E Cohen; Kevin D Cooper; Kelly M Cordoro; Dawn M Davis; Steven R Feldman; Jon M Hanifin; David J Margolis; Robert A Silverman; Eric L Simpson; Hywel C Williams; Craig A Elmets; Julie Block; Christopher G Harrod; Wendy Smith Begolka; Robert Sidbury
Journal:  J Am Acad Dermatol       Date:  2014-05-09       Impact factor: 11.527

Review 2.  [Adequate prescription and application of topicals : How to calculate the right volume for the prescription of ointment needed?]

Authors:  D Homayoon; P Dahlhoff; M Augustin
Journal:  Hautarzt       Date:  2018-06       Impact factor: 0.751

3.  Systemic Tofacitinib Concentrations in Adult Patients With Atopic Dermatitis Treated With 2% Tofacitinib Ointment and Application to Pediatric Study Planning.

Authors:  Vivek S Purohit; William C Ports; Cunshan Wang; Steve Riley
Journal:  J Clin Pharmacol       Date:  2018-12-17       Impact factor: 3.126

Review 4.  Current Perspectives on the Management of Infantile Atopic Dermatitis.

Authors:  Danielle R Davari; Elizabeth L Nieman; Diana B McShane; Dean S Morrell
Journal:  J Asthma Allergy       Date:  2020-11-05
  4 in total

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